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Reimagining circularity : Actions for optimising the use of existing buildings

Transitioning towards a circular economy, where the existing building stock is more efficiently used, would significantly reduce material and energy use, emissions, and waste from the built environment sector. This study focuses on exploring what conditions are needed for circularity by imagining preferable circular futures for a 2035 timeframe and understanding the required actions to achieve the

Assessment of Vascular Contributions to Cerebral Small Vessel Disease: Data from the general population study "Good Aging in Skåne"

Cerebral small vessel disease (CSVD) are highly age-related pathologies isualized by neuroimaging. CSVD can be silent lesions but are associated with cognitive decline, dementia, gait disorders, depression and stroke. A growing body of evidence links CSVD to systemic vascular processes, but the pathophysiology is not fully explained. The aim of this thesis is to investigate possible links between

Mind the Body : Verbal and Non-verbal Signs of Choice Awareness

This doctoral thesis explores the phenomenon of choice awareness through an interdisciplinary framework grounded in cognitive semiotics. Combining phenomenological philosophy with empirical investigations, the thesis examines how awareness of choice manifests across different levels of consciousness and within diverse semiotic systems. Papers 1 to 3 present experimental studies using choice manipu

Quantitative Imaging in Radionuclide Therapy with Lutetium-177 : Towards Traceability and Comparability

Radionuclide therapy involving 177Lu-labelled somatostatin analogues for the treatment of neuroendocrine tumours isincreasing. While the treatment is currently administered according to a standard protocol, patient-specific treatmentsbased on dosimetry are believed to be beneficial. However, commonly adopted dosimetry procedures are lacking, andlocally developed dosimetry methods are used, which mRadionuclide therapy involving 177Lu-labelled somatostatin analogues for the treatment of neuroendocrine tumours isincreasing. While the treatment is currently administered according to a standard protocol, patient-specific treatmentsbased on dosimetry are believed to be beneficial. However, commonly adopted dosimetry procedures are lacking, andlocally developed dosimetry methods are used, which m

Prolonging Survival in Glioblastoma: Modeling the Effects of Gabapentin and the Modulatory Role of Dexamethasone

Bland vuxna hjärntumörer utmärker sig glioblastom (GBM) genom sin höga förekomst och allvarliga förlopp, och kännetecknas av snabb tumörtillväxt och sin ogynnsamma prognos. Gabapentin är ett läkemedel som ofta används vid nervsmärta och epilepsi, och har nyligen uppmärksammats för sin möjliga påverkan på samspelet mellan tumör och nervsystem med potentiella konsekvenser för GBMs förlopp. I denna Among adult brain cancers, glioblastoma (GBM) stands out for its frequency and severity, characterized by rapid progression and poor prognosis. Gabapentin, a gabapentinoid widely prescribed for managing neurological conditions such as neuropathic pain and seizures, has been proposed to influence tumor-neural interactions and modulates glioblastoma outcomes. This study used real-world clinical data

Material Memory : Rewriting Without Erasing - Reimagining industrial heritage for contemporary civic use

This thesis investigates the adaptive reuse of Vagnsverkstaden, a former railway maintenance hall in Malmö’s Lokstallarna. The project explores how this early 20th-century industrial structure can be transformed into a multifunctional civic space, while preserving its material and historical character. Using site analysis, theoretical frameworks, and case study comparisons, the proposal introduces

Nephrotoxicity Surveillance for Childhood and Young Adult Survivors of Cancer : Recommendations From the International Late Effects of Childhood Cancer Guideline Harmonization Group

PURPOSE Childhood, adolescent, and young adult (CAYA) survivors of cancer are at risk of nephrotoxicity. Surveillance guidelines are important for timely diagnosis and treatment of these survivors, which could slow the progression to higher stages of kidney dysfunction. METHODS The International Late Effects of Childhood Cancer Guideline Harmonization Group established a multidisciplinary panel of

Thresholds for Contact Allergy to a Rubber Accelerator : TETD—Determined by Serial Dilution Patch Testing and a Simulated Glove-Use Model

Background: Rubber accelerators found in rubber gloves may cause contact allergy and thus allergic contact dermatitis. Objectives: To investigate which doses of tetraethylthiuram disulfide (TETD) elicit allergic contact dermatitis by patch testing and in a repeated occluded application test simulating glove use. Patients and Methods: A multicentre study was conducted. Eight patients with contact a

Touring the carbon ruins : Towards an ethics of speculative decarbonisation

For many years, questions about the future have been marginalised within the social sciences: asking how we might live in a post-fossil society, or what are the key decisions and events that could take us there, has been seen as outside of the disciplinary scope. In this chapter – which takes as its point of departure the ‘speculative turn’ that is increasingly inspiring a range of works, from for

Regenerative performance and immunogenicity of engineered extracellular matrices.

Critical-sized bone defects remain a significant unmet clinical need, with > 500,000 reconstructive procedures performed annually in the United States and Europe and associated costs exceeding US$3 billion. Autologous bone grafting—the current gold standard—suffers from limited harvest volume and donor-site morbidity, whereas allografts show variable integration and carry immunological and infecti

Working to overcome the fear of student discomfort and peer judgment while teaching for sustainability

How we teach is strongly influenced by the culture we teach in, especially what (we believe) our colleagues think is good and acceptable. Understanding the reluctance to changes in teaching practice, including fear of disapproval from colleagues and students, investigating and reappraising those fears, and starting to talk about alternative interpretations is a first step towards overcoming the in

Student views on active learning in the geoscience curriculum

Active learning is increasingly implemented in higher education, yet students' perspectives on this pedagogical approach remain diverse. This study explores geoscience students' views on active learning within a course at the University of Bergen (UiB) and in relation to their broader study program. Through longitudinal qualitative interviews with two student cohorts, we identified seven main cate

Bridging the Intention-Action Gap: The Role of Self-Control and Entrepreneurial Passion among Entrepreneurship Graduates

This thesis examines how psychological traits, specifically self-control and entrepreneurial passion, interact with entrepreneurial intention to predict entrepreneurial action among graduates of a Master's programme in Entrepreneurship and Innovation at Lund University. Guided by the Rubicon Model of Action Phases, we distinguish between the formation of entrepreneurial intention (predecisiona

Unraveling Tourist Behavior in Tehran’s Rural Fringe : Moral Norms and Environmental Concerns in Shemiranat’s Biodiversity

This study extends the Theory of Planned Behavior by incorporating moral norms and environmental concerns to investigate factors influencing tourists’ biodiversity conservation behaviors in ecologically sensitive destinations. The extended TPB model examines environmental attitudes, subjective norms, perceived behavioral control, moral norms, and environmental concerns. Using a mixed-method approa

Risk factors for the development of knee osteoarthritis across the lifespan : A systematic review and meta-analysis

Objective: To identify and quantify risk factors for incident knee osteoarthritis (KOA) across the lifespan. Methods: This systematic review and meta-analysis identified eligible studies from seven electronic databases and three registries. Longitudinal cohort studies or randomised controlled trials evaluating participants who developed incident symptomatic and/or radiographic KOA were included. T