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Non-adherence to immunosuppressants after lung transplantation- a common risk behavior

Background:After lung transplantation, life-long treatment with immunosuppressive medication is required to prevent rejection and graft loss but adherence to immunosuppressive treatment may be difficult for the lung recipient. Adherence is essential and non-adherence to immunosuppressive treatment can lead to graft loss and death.Objective:The aim of this cross-sectional study was to investigate t

Environment and Sustainability

There are strong links between astrobiology and environmental concern. Astrobiology is the study of the origin, evolution and distribution of life in the universe—including Earth. Understanding life, and in particular the basic conditions for life, is important for our ability to create a sustainable future on Earth. The connection goes both ways, however. The preservation of biodiversity and of p

Fatigue 1-5 years after lung transplantation-a multi center cross-sectional cohort study

The aim of this study was to investigate the prevalence of fatigue among lung recipients 1–5 years after transplantation (LuTx) and to explore its relationship to distressing symptoms such as dyspnea, sleep problems, pain, and decreased appetite, as well as psychological and transplant specific wellbeing. A cross-sectional, multicenter cohort study was conducted. A total of 117 lung recipients wit

Uncertainty and self-efficacy in parents of a child with congenital cataract- new implications for practice

AimThe aim was an in‐depth exploration of uncertainty and self‐efficacy among parents of a child with congenital cataract by means of two theoretical frameworks to re‐design family care.DesignA directed content analysis in accordance with Hsieh & Shannon, using Mishel's theory of uncertainty and Bandura's self‐efficacy theory.MethodsOpen‐ended, in‐depth interviews were conducted with 23 parent

Perceptions of experiences of having a sibling stem cell donor

Objective: The aim was to explore stem cell recipients’ perceptions of experiences of having a sibling donor from pretransplantation to one year afterwards in order to support their learning process.Methods: Ten adult recipients, five women and four men, with a mean age of 52 years (19-68 years) receiving stem cells from a sibling donor were included consecutively. We used a phenomenographic appro

Sibling stem cell donors' perceptions of experiences of donation

Objective: What and when should we tell sibling donors about the donation process? Although we provide extensive information to sibling stem cell donors, we lack knowledge of their perceptions and how they change during the donation process. Therefore, the aim of this study was to explore sibling donors’ perceptions of experiences of stem cell donation from pre-donation to one year afterwards.Meth

Chronic pain 1-5 years after lung transplantation

Chronic bodily pain after lung transplantation has received little attention. Therefore, the aim was to provide a multidimensional assessment of self-reported chronic pain 1-5 years after lung transplantation and its relationship with self-reported psychological general well-being (PGWB) and self-efficacy. This multicenter, cross-sectional study is a part of the Swedish national study: Self-manage

For and against organ donation and transplantation- intricate facilitators and barriers in organ donation perceived by German nurses and doctors

Background. Significant facilitators and barriers to organ donation and transplantation remain in the general public and even in health professionals. Negative attitudes of HPs have been identified as the most significant barrier to actual ODT. The purpose of this paper was hence to investigate to what extent HPs (physicians and nurses) experience such facilitators and barriers in ODT and to what

Att utveckla arbetsidentitet hos unga vuxna med psykisk ohälsa

Bakgrund: Hur vi identifierar oss är starkt kopplat till arbete. Unga vuxna är en känslig grupp när det gäller inträde på arbetsmarknaden. Om de också har psykisk ohälsa blir det ännu svårare och risken för marginalisering ökar. Likväl har arbete visat väsentlig betydelse för en personlig återhämtning. Syftet med studien var att utforska erfarenheter bland unga vuxna med psykisk ohälsa som börjar

Determining Dependency structures and estimating nonlinear regression errors without doing regression

A general method is discussed, the δ-test, which establishes functional dependencies given a table of measurements. The approach is based on calculating conditional probabilities from data densities. Imposing the requirement of continuity of the underlying function the obtained values of the conditional probabilities carry information on the variable dependencies. The power of the method is illust

TFAP2B-Dietary protein and glycemic index interactions and weight maintenance after weight loss in the diogenes trial

Background:TFAP2B rs987237 is associated with obesity and has shown interaction with the dietary fat-to-carbohydrate ratio, which has an effect on weight loss. We investigated interactions between rs987237 and protein-to-carbohydrate ratio or glycemic index (GI) in relation to weight maintenance after weight loss. Methods: This study included 742 obese individuals from 8 European countries who par

Change in proportional protein intake in a 10-week energy-restricted low- or high-fat diet, in relation to changes in body size and metabolic factors

Objective: To investigate in a secondary analysis of a randomised trial the effects of a low-/high-fat diet and reported change from baseline in energy% from protein (prot%), in relation to changes in body size and metabolic factors. Methods: Obese adults (n = 771) were randomised to a 600 kcal energy-deficient low-fat (20-25 fat%) or high-fat (40-45 fat%) diet over 10 weeks. Dietary intake data a

TFAP2B influences the effect of dietary fat on weight loss under energy restriction

Background: Numerous gene loci are related to single measures of body weight and shape. We investigated if 55 SNPs previously associated with BMI or waist measures, modify the effects of fat intake on weight loss and waist reduction under energy restriction. Methods and Findings: Randomized controlled trial of 771 obese adults. (Registration: ISRCTN25867281.) One SNP was selected for replication i

Association between sleep duration and overweight : The importance of parenting

Objective:Sleep duration has been related to overweight in children, but determinants of sleep duration are unclear. The aims were to investigate the association between sleep duration and childhood overweight adjusted for family characteristics and unhealthy behaviours, to explore determinants of sleep duration and to determine with sleep competing activities.Method:A cross-sectional study was ca

Blood pressure, body size and prostate cancer risk in the Swedish construction workers cohort

Data from prospective studies on blood pressure and prostate cancer risk are limited, and results are inconclusive. Baseline measurements of height, weight and blood pressure were available in 336,159 men in the Swedish Construction Workers cohort. During an average of 22.2 years of follow-up, 10,002 incident cases and 2,601 fatal cases of prostate cancer were identified in National registers. For