Filtyp
Antigens of the clinically important ABO and P1PK blood group systems are carbohydrate structures. Thus the underlying genes do not encode antigens directly but glycosyltransferases that add specific sugar molecules to selected precursor chains. The aim of this study was to investigate the transcriptional regulation of ABO and A4GALT, with an emphasis on interindividual differences. The up-and dow
Objective: Type 2 diabetes is heterogeneous in its clinical features, pathogenesis, and predisposing or causal genetic factors. This report examines what is known and what needs to be learned about the potential to individualize glycemic therapies in type 2 diabetes, based on phenotypes and genotypes. Participants: A 29-member international working group with expertise in diabetes epidemiology, ph
Objective: This study evaluates the effect of food intake on commonly used pulsed Doppler and tissue Doppler measurements. Methods: Twenty-three healthy subjects aged 25.6 ± 4.5 years were investigated. A wide selection of pulsed Doppler and tissue Doppler variables were measured before a standardized meal as well as and 30 and 110 minutes afterwards. Results: The following variables increased si
Paraquat is a widely used herbicide that is structurally similar to the known dopaminergic neurotoxicant 1-methyl-4-phenyl-pyridine and acts as a potential etiologic factor for the development of Parkinson's disease. In this study, we investigated the protective roles of lipocalin-type prostaglandin (PG) D synthase (L-PGDS) against paraquat-mediated apoptosis of human neuronal SH-SY5Y cells. The t
Styrelsens och revisorernas skadeståndsansvar enligt aktiebolagslagens 15 kap.
Approximation and online algorithms with applications in robotics and computational biology.
I maj 2004 påbörjades ett nytt projekt vid Lunds Tekniska Högskola som handlar om biologisk påväxt på mineraliska fasader. Projektet finansieras av FORMAS. Bakgrunden till projektet var att flera fall av nybyggda putsade fasader fick kraftig påväxt inom bara några år efter putsningen. Flera pilotförsök blev genomförda för att undersöka problemet i detalj och en sammanfattning av dessa redovisades
Feature om den grafiske designern och filmskaparen Saul Bass.
Disorders affecting the central nervous system have proven particularly hard to treat and disappointingly few of novel therapies have reached the clinics in the last decades. A better understanding of the physiological processes in the brain underlying various symptoms could therefore greatly improve the rate of progress in this field. We here show how systems level descriptions of different brain
