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Lack of Opsonic Antibody Responses to Invasive Infections With Streptococcus dysgalactiae

Introduction: Streptococcus dysgalactiae can cause severe recurrent infections. This study aimed to investigate antibody responses following S. dysgalactiae bacteraemia and possible development of protective immunity. Materials and Methods: Patients with S. dysgalactiae bacteraemia in the county of Skåne between 2017 and 2018 were prospectively included. Acute and convalescent sera were obtained.

New and Practical Formulation for Overlaps of Bogoliubov Vacua

In this Letter, we present a new expression for the overlaps of wave functions in Hartree-Fock-Bogoliubov based theories. Starting from the Pfaffian formula by Bertsch et al. [1], an exact and computationally stable formula for overlaps is derived. We illustrate the convenience of this new formulation with a numerical application in the context of the particle-number projection method. This new fo

Näthat och demokratiskt deltagande – en kunskapsöversikt

Rätten att uttrycka åsikter, att kritisera och att ifrågasätta är en del av enlevande demokrati. Ett demokratiskt samhälle måste vara öppet för olikaröster och ge alla möjlighet att komma till tals. Demokratin är beroendeav att människor deltar och engagerar sig i samhällsfrågor. Med rättentill yttrandefrihet kommer också ett ansvar. Var och en bör skydda, värnaoch bevara yttrandefriheten genom at

MTT and Blood-Brain Barrier Disruption within Asymptomatic Vascular WM Lesions

BACKGROUND AND PURPOSE: White matter lesions of presumed ischemic origin are associated with progressive cognitive impairment and impaired BBB function. Studying the longitudinal effects of white matter lesion biomarkers that measure changes in perfusion and BBB patency within white matter lesions is required for long-term studies of lesion progression. We studied perfusion and BBB disruption with

Listening effort and fatigue in native and non-native primary school children

Background noise makes listening effortful and may lead to fatigue. This may compromise classroom learning, especially for children with a non-native background. In the current study, we used pupillometry to investigate listening effort and fatigue during listening comprehension under typical (0 dB signal-to-noise ratio [SNR]) and favorable (+10 dB SNR) listening conditions in 63 Swedish primary s

Patients and Professionals as Partners in Hypertension Care : Qualitative Substudy of a Randomized Controlled Trial Using an Interactive Web-Based System Via Mobile Phone

BACKGROUND: The use of technology has the potential to support the patient´s active participation regarding treatment of hypertension. This might lead to changes in the roles of the patient and health care professional and affect the partnership between them.OBJECTIVE: The aim of this qualitative study was to explore the partnership between patients and health care professionals and the roles of p

Inre motivation positiv för elevers utveckling och lärande

Har yttre belöningar (exempelvis guldstjärnor i kanten av skrivboken) en negativ inverkan på elevers inre motivation? Minskar intresset för människor att engagera sig i eller prestera väl i en uppgift när yttre belöningar erbjuds? Flera meta-analyser har visat att så är fallet. Self-Determination Theory (SDT) är en teori som såväl teoretiskt som praktiskt belyser hur lärare kan stödja elever för a

The transformation of labour market regulatory institutions

The aim of this paper is to explore the European Social Dialogue as a regulatory institution and its transformation in a context where the values framing labour law have changed from socialistic to neo-liberal. The paper will highlight the European Social Dialogue as an autopoietic system of industrial relations and the analysis will be carried out through a methodologically holistic model in two

Globalisation of labour markets and international systems of industrial relations

This paper explores the need for and more so the possibility of developing international systems of industrial relations in response to the increasing globalisation of labour markets. Due to increasing internationalisation of employment relations national systems of collective bargaining and industrial relations have become challenged. The reason is that the scope of their competences is limited t

Copeptin as a predictive marker of incident heart failure

AIMS: Heart failure (HF) is a common disease with increasing prevalence and poor prognosis. The vasopressin (VP) marker copeptin predicts development of diabetes mellitus, diabetic heart disease, coronary artery disease, and premature mortality. Copeptin is elevated in HF patients and predicts a worse outcome. This study aims to investigate whether copeptin can predict HF development.METHODS: Cope

Ventriculostomy-related infections in subarachnoid hemorrhage patients-a retrospective study of incidence, etiology, and antimicrobial therapy

BACKGROUND: This study was performed to investigate the incidence and etiology of ventriculostomy-related infections (VRIs) in patients with subarachnoid hemorrhage (SAH) and to assess adherence to local clinical guidelines regarding empirical antimicrobial therapy and diagnostic routines.METHODS: A total of 191 consecutive SAH patients treated in the neuro-intensive care unit of Uppsala Universit

T cells, B cells, and PD-L1 expression in esophageal and gastric adenocarcinoma before and after neoadjuvant chemotherapy : relationship with histopathological response and survival

Perioperative chemotherapy enhances the survival rates for patients with esophageal and gastric (EG) adenocarcinoma, but not all patients benefit from this additional treatment. Chemotherapeutic agents have been demonstrated to alter the immune cell (IC) composition in the tumor microenvironment. Hence, there is a rationale to investigate the influence of neoadjuvant chemotherapy (NAC) on differen

Increased inflammatory response in cytomegalovirus seropositive patients with Alzheimer's disease

Alzheimer's disease (AD) has been associated with increased local inflammation in the affected brain regions, and in some studies also with elevated levels of proinflammatory cytokines in peripheral blood. Cytomegalovirus (CMV) is known to promote a more effector-oriented phenotype in the T-cell compartment, increasing with age. The aim of this study was to investigate the inflammatory response of

Properties and emission factors of cloud condensation nuclei from biomass cookstoves - Observations of a strong dependency on potassium content in the fuel

Residential biomass combustion is a significant source of aerosol particles on regional and global scales influencing climate and human health. The main objective of the current study was to investigate the properties of cloud condensation nuclei (CCN) emitted from biomass burning of solid fuels in different cookstoves mostly of relevance to sub- Saharan east Africa. The traditional three-stone fi

Sibling rank and sibling number in relation to cardiovascular disease and mortality risk : A nationwide cohort study

Background The number and rank order of siblings could be of importance for risk of cardiovascular disease and mortality. Previous studies have used only fatal events for risk prediction. We, therefore, aimed to use also non-fatal coronary and cardiovascular events in fully adjusted models. Methods From the Multiple-Generation Register in Sweden, data were used from 1.36 million men and 1.32 milli