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A Bedside Method for Measuring Effects of a Sedative Drug on Cerebral Function in Newborn Infants

Background: Data on the cerebral effects of analgesic and sedative drugs are needed for the development of safe and effective treatments during neonatal intensive care. Electroencephalography (EEG) is an objective, but interpreter-dependent method for monitoring cortical activity. Quantitative computerized analyses might reveal EEG changes otherwise not detectable. Methods: EEG registrations were

Using machine learning to determine acceptable levels of groundwater consumption in Iran

Groundwater footprint index (GFI) is an essential indicator to assess the sustainability of groundwater aquifers. Prediction of future GFI can significantly help managers and decision-makers of groundwater supply to better plan for future resilient consumption of surface and groundwater. In this context, artificial intelligence and machine learning models can aid to predict GFI in view of lacking

UKRAINIAN REFUGEES IN SCANDINAVIA, OR HOW TO TALK ABOUT MIGRATION WITHOUT TALKING ABOUT IT

The reaction to Russia’s full-scale invasion of Ukraine in February 2022 indicated a multiplicity of standpoints, different positionalities, and power asymmetries, in particular in the Western academy. Represen-tatives of the mainstream migration research centres as well as individual researchers, while recognising the importance of solidarity with the Ukrainian people and with Ukrainian scholars,

Minority governments in Sweden : Majority cabinets in disguise

This chapter focuses on governments in Sweden, a country which has a relatively high share of minority governments, over 70 percent, in the post-war period. Most governments formed during this period have been single-party Social Democratic cabinets, supported by one or more parties in parliament, but there have also been several cases of minority coalitions. Swedish politics has historically been

Small-scale spatial patterns of bulk atmospheric deposition

In total 14 bulk atmospheric deposition collectors were distributed over the city of Lund (about 20 km~) in the south of Sweden during September 1980 to June 1981. The observations were made to investigate small-scale spatial variability of atmospheric deposition. Monthly bulk deposition samples were analyzed for CI, Ptot, Zn, Cu, and Pb.Correlation analysis shows that the spatial scale for the va

Oxidative Stress and Its Relation to Lower Urinary Tract Symptoms

The aim of this review is to discuss how to link lower urinary tract symptoms (LUTS) and oxidative stress (OS) and to define relevant targets for therapeutic intervention. Narrative review based on published literature. Many of the multifactorial pathophysiological mechanisms behind LUTS can initiate reactive oxygen species (ROS) generation. Assuming that OS is a consequence rather than a primary

Reasoning with Expectations About Causal Relations

Reasoning is not just following logical rules, but a large part of human reasoning depends on our expectations about the world. To some extent, non-monotonic logic has been developed to account for the role of expectations. In this article, the focus is on expectations based on actions and their consequences. The analysis is based on a two-vector model of events where an event is represented in te

Determination of the Complex-Valued Elastic Moduli of Polymers by Electrical-Impedance Spectroscopy for Ultrasound Applications

A method is presented for the determination of complex-valued compression and shear elastic moduli of polymers for ultrasound applications. The resulting values, which are scarcely reported in the literature, are found with uncertainties typically around 1% (real part) and 6% (imaginary part). The method involves a setup consisting of a cm-radius, mm-thick polymer ring glued concentrically to a di

Effect of Reynolds number and a low-intensity freestream turbulence on the flow around a circular cylinder

This paper presents experimental results from measurements on circular cylinders of differentdiameters in cross flow. The Reynolds number was varied from about 50 to 2·105. Thecombined effects of Reynolds number and a low-intensity freestream turbulence (Tu =1.4%)on the variation of different coefficients, e.g., Strouhal number, mean and RMS pressurecoefficients, are presented. The results indicat

Non-Fungible Tokens as a Framework for Sustainable Innovation in Pharmaceutical R&D: A Smart Contract-Based Platform for Data Sharing and Rightsholder Protection

Research and Development (R&D) in the pharmaceutical sector traditionally occurred in closed, siloed institutional settings. This approach was a function of a rights-oriented model which framed access and reuse of data (data sharing) as a threat to rights-holders. However, a closed model of explorative collaboration is less suited to today’s more complex scientific ecosystem, where external en

Predicting the Solubility of Inorganic Ion Pairs in Water

Polyoxometalates (POMs), ranging in size from 1 to 10’s of nanometers, resemble building blocks of inorganic materials. Elucidating their complex solubility behavior with alkali-counterions can inform natural and synthetic aqueous processes. In the study of POMs ([Nb24O72H9]15−, Nb24) we discovered an unusual solubility trend (termed anomalous solubility) of alkali-POMs, in which Nb24 is most solu

Polyoxoniobates as molecular building blocks in thin films

Niobium oxide thin films have been prepared by spin-coating aqueous solutions of tetramethylammonium salts of the isostructural polyoxometalate clusters [Nb10O28]6-, [TiNb9O28]7- and [Ti2Nb8O28]8- onto silicon wafers, and annealing them. The [Nb10O28]6- cluster yields films of Nb2O5 in the orthorhombic and monoclinic crystal phases when annealed at 800 °C and 1000 °C, respectively, whereas the [Ti

Cerebrospinal fluid neurofilament light predicts longitudinal diagnostic change in patients with psychiatric and neurodegenerative disorders

Objective People with neuropsychiatric symptoms often experience delay in accurate diagnosis. Although cerebrospinal fluid neurofilament light (CSF NfL) shows promise in distinguishing neurodegenerative disorders (ND) from psychiatric disorders (PSY), its accuracy in a diagnostically challenging cohort longitudinally is unknown. Methods We collected longitudinal diagnostic information (mean=36 mon

The effect of uncertainty on stock market volatility and correlation

In this study, we use an extension of the heterogeneous autoregressive model to investigate the influence of time-varying risk aversion and macroeconomic, financial, and economic policy uncertainty measures on stock market volatility and correlation. Based on the findings, there is a stronger predictive ability of these variables at the monthly frequency than at the daily frequency. We also highli

Inner transitions in higher education in Sweden: incorporating intra-personal skills in education for sustainable development

Humanity is facing an unprecedented challenge of climate crises. Rapid changes to the physical environment and living conditions will be accompanied by challenges to mental health and well-being. Consequently, education for sustainable development should also include coping strategies for stress and anxiety. Adding intra-personal skills to the curriculum, such as self-reflection and mindfulness tr

Regionala riktlinjer vid förskrivning av beroendeframkallande läkemedel i Region Skåne

Sammanfattande kommentarer och rekommendation • Opioider och bensodiazepiner är kraftfulla läkemedel med god patientnytta i utvalda fall och under begränsade behandlingstider.• Läkare/vårdenhet som initierat förskrivning har ansvar för denna tills den upphört eller tills annaninstans accepterat övertag – Behandlingsansvar• Basbehandling – överväg alltid först alternativa behandlingsstrategier, såv

Extracorporeal Membrane Oxygenation: Set-up, Indications, and Complications

Extracorporeal membrane oxygenation (ECMO) occupies an increasingly important position in the clinic for the management of cardiac and/or pulmonary failure. As a rescue therapy, ECMO can support patients following respiratory or cardiac compromise to act as a bridge to recovery, to decision, or to transplant. This chapter reviews briefly the history of ECMO implementation as well as device modes,

Reevaluating the protective effect of smoking on preeclampsia risk through the lens of bias

Preeclampsia is a hypertensive disorder that is usually diagnosed after 20 weeks' gestation. Despite the deleterious effect of smoking on cardiovascular disease, it has been frequently reported that smoking has a protective effect on preeclampsia risk and biological explanations have been proposed. However, in this manuscript, we present multiple sources of bias that could explain this association

Digital Disruption and Rethinking the ‘Script’ of Peace Mediation

This article focuses on the quest for digitalisation in peace mediation and to the extent to which digital disruption is reshaping its practices. While digitalisation in the wider field of diplomacy has seen dramatic changes in its practices, peace mediation is a ‘latecomer’. The article explores the constitutive effects on specific norms and practices of peace mediation and identifies opportuniti