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Abstract in Undetermined Background: Measured or modeled levels of outdoor air pollution are being used as proxies for individual exposure in a growing number of epidemiological studies. We studied the accuracy of such approaches, in comparison with measured individual levels, and also combined modeled levels for each subject's workplace with the levels at their residence to investigate the influe
DNA methylation at CpG dinucleotides is modified in tumorigenesis with potential impact on transcriptional activity.
Diabetes is a group of metabolic diseases characterized by the inability of the organism to autonomously regulate the blood glucose levels. It requires continuing medical care to prevent acute complications and to reduce the risk of long-term complications. Inadequate glucose control is associated with damage, dysfunction and failure of various organs. The management of the disease is non trivial
In this work three in vitro methods for the measurement of mucoadhesion have been compared: ellipsometry, tensile strength and rheology. The conditions used for the three methods have been as similar as possible. Six different polymers were investigated: sodium carboxymethyl cellulose (CMC), hydroxyethyl cellulose (HEC), chitosan, polyvinyl pyrrolidone (PVP) and two cross-linked polyacrylic acids,
Background: Macrophage migration inhibitory factor (MIF) has been proposed to play a detrimental role in stroke. We recently showed that MIF promotes neuronal death and aggravates neurological deficits during the first week after experimental stroke, in mice. Since MIF regulates tissue inflammation, we studied the putative role of MIF in post-stroke inflammation. Methods: We subjected C57BL/6 mice
Popular Abstract in Swedish Att bär är nyttigt är ett påstående som de flesta känner igen. På butikshyllorna trängs våra nordiska bär med exotiska ”superbär” som utlovar att göra oss friska. Men vilka hälsoeffekter kan egentligen uppnås genom att äta bär? Är vissa bär mer nyttiga än andra? Forskningsresultaten som presenteras i denna avhandling visar att lingon, svarta vinbär och blåbär kan motverThe increasing prevalence of obesity is a worldwide health problem closely linked to diet and lifestyle factors. Obesity is associated with increased risk of several metabolic disorders including insulin resistance, nonalcoholic fatty liver disease and type 2 diabetes. Hence, there is a great need to identify dietary strategies for the prevention of obesity and related diseases. This thesis invest
Sugarcane bagasse was subjected to steam pretreatment impregnated with hydrogen peroxide. Analyses were performed using 2(3) factorial designs and enzymatic hydrolysis was performed at two different solid concentrations and with washed and unwashed material to evaluate the importance of this step for obtaining high cellulose conversion. Similar cellulose conversion were obtained at different condi
A majority of the machining processes in the industry of today is performed using position-controlled machine tools, where conservative feed rates have to be used in order to avoid excessive process forces. By instead controlling the process forces, the feed rate, and consequently the material removal rate, can be maximized. In turn, this leads to decreased cycle times and cost savings. Furthermor
Mineralkvävegödsel är en av förutsättningarna för de höga skördenivåer som uppnåtts i det industrialiserade, moderna jordbruket. I Sverige finns idag ingen inhemsk produktion av mineralkvävegödsel, utan hela efterfrågan tillgodoses med import från utlandet. Produktionen är idag baserad på fossila resurser, vilka används både som råvara för produktionen och som energi för att driva processerna. Vi Mineral nitrogen fertilizer is one of the main reasons for the high yields in modern, industrial agriculture. There is currently no production of mineral nitrogen fertilizer in Sweden – the entire demand is met by imports from abroad. Global production is at present based on fossil resources, which are used both as raw materials for the production and as energy to fuel the process. We are thus dep
Popular Abstract in Swedish Hårfrisörer utsätts dagligen för en mängd kemikalier på arbetet. Många frisörer drabbas därför av luftvägsbesvär vilka ofta kan kopplas till hårblekningsmedel. Blekningsmedlen innehåller bland annat så kallade persulfater. Dessa tros vara en av huvudorsakerna till luftvägsbesvären. Flera studier har visat att persulfater kan ge symptom från luftvägarna såsom hösnuva ellHairdressers have an increased risk for developing airway symptoms e.g. asthma and rhinitis. Persulfate salts, which are oxidizing agents present in bleaching powder, are considered to be important causal agents for these symptoms. The underlying mechanisms are unclear and efficient tools for risk assessment and diagnosis are scarce. The general aim of this thesis was to measure proteomic changes,
In the book ”street-level bureaucracy dilemmas of the individual in public services” (2010) the author Michael Lipsky writes about the individual in public services. Lipsky presents a theory about street-level bureaucrats as policy makers. He argues that policy is created by the people at the bottom of the organizational hierarchy, the street-level bureaucrats. This is made possible by two interli
The European Union aims at being an ethical actor on the global arena and the EU development-policy is directed towards achieving long-term socio-economic development, with a specific focus on Sub-Saharan Africa, where development is showing little progress, and food security and agricultural development is at the top of the agenda. The EU is both the biggest market and the biggest aid-donor for
Uppsatsen behandlar internprissättning av koncerninterna lån i ljuset av den svenska rätten. Internpriset är det pris ett visst bolag, eller en viss del av ett företag, debiterar ett närstående företag i en annan jurisdiktion för varor och tjänster som köpts. Grundregeln är att sådan prissättning skall ske på en nivå som motsvarar den två oberoende parter hade enats om under liknande omständigheteThe paper deals with transfer pricing of inter-company loans with regards to the Swedish law. The transfer price is the price at a certain company or a certain part of a company, charges a related company in another jurisdiction for goods and services purchased. The fundamental rule is that such pricing shall be on a level corresponding to the one which two independent parties would have agreed up
Purpose: Management autobiographies are an important discourse in today’s management literature and we believe that they have become a great influence on management practitioners. In this study we aim to analyse how CEOs portray themselves in their autobiographies. Methodology: Our data consists of four selected autobiographies from the criteria that they should be bestsellers, written by a
In this thesis, I have attempted to understand how young people are using social media tools to increase capabilities. The primary fieldwork was carried out in Harare, Zimbabwe. A qualitative study was completed, employing Sen's (1999) Capability Approach, adapted by various authors to account for the role of information and communication technologies. After presenting empirical analysis, the
Employment integration of non-Swedish residents into the Swedish labor market increasingly sparks political debate and begs further exploration. While some scholars try to focus on pre-arrival characteristics as determinants of an immigrant’s future employment prospects, this project attempts to examine the degree to which municipal-level conditions influence the local employment rate amongst non-
The aim of this thesis is to investigate the features of the Swedish parliamentary parties’ immigration-discourse regarding discursive discrimination in the election campaigns of 2002 and 2010. Immigration-discourse here both includes what is said and written about different categories of immigrants and aspects of integration. This is approached from a critical discourse analytical perspective wit
