In the course of a screening for cytotoxic Compounds from fungi four new terpenoid metabolites, named dasyscyphins A, B, C, and niveulone were isolated from fermentations of Dasyscyphus niveus strain A0101. While dasyscyphin A (1) exhibited no significant biological activities in our test systems dasyscyphin B (2) and dasyscyphin C (3) showed cytotoxic activities against human (HepG2, Hela S3, U93

We have developed a transgenic mouse expressing the Cre recombinase under control of a tetracycline-responsive promoter. Using a CamKIIalpha-driven tTA transgenic strain and a lacZ reporter mouse, we obtained the expected neuronal pattern of recombination in the olfactory lobe, cortex, striatum, hippocampus and Purkinje cells. Moreover, recombination can be completely abolished by feeding the mice

This paper is concerned with question of how to assess results of networking which is an important element in movement towards sustainable development. Although based upon a large body of research, including empirical studies, the question of assessment of the networking results remains un-addressed, to a large extent. Based on an in-depth analysis of two Swedish tourism networks for sustainabilit

A shift in business thinking from selling products to providing service solutions to customer needs is becoming noticeable. It is driven by increasing competition and the need to identify new profit centres for producers of mature products. This paper identifies a new product group that could be interesting from the product-service system perspective - baby prams. The study presents a new business

The redox behavior of two synthetic manganese complexes illustrates a mechanistic aspect of importance for light-driven water oxidation in Photosystem 11 (PSII) and design of biomimetic systems (artificial photosynthesis). The coupling between changes in oxidation state and structural changes was investigated for two binuclear manganese complexes (1 and 2), which differ in the set of first sphere

I denna uppsats försöker jag med åtskilliga exempel påvisa att förhållandet mellan det gamla och det nya förbundet är ett centralt tema i Uppenbarelseboken.

A new permutor design for serially concatenated convolutional codes is presented. It is based on the construction of a permutation matrix without short cycles of special types. For such a permutor, we give a lower bound on the minimum distance of the overall code that is significantly larger than that achievable with first-order separation (spreading factors). Additionally, the minimum distance ca

A thermoseparating random copolymer (Ucon 50-HB-5100) composed of (50%) ethylene oxide and (50%) propylene oxide has been used to form an aqueous two-phase system by heating the polymer-water solution above the cloud point of the copolymer. In the formed two-phase system a water rich top phase is in equilibrium with an aqueous polymer rich bottom phase. The partitioning of amino acids and peptides

The C-terminal perlecan domain V of about 90 kDa consists of laminin-type G domain modules (LG) (25 kDa) and epidermal growth factor-like modules (EG) (4 kDa) in the tandem arrangement LG1-EG1-EG2-LG2-EG3-EG4-LG3. Several shorter fragments have been prepared by recombinant production in mammalian cells and used to map the single glycosaminoglycan (GAG) substitution site and the binding of several

There is growing interest in developing a conceptual understanding of the experience of balance in everyday life, from an occupational perspective. The purpose of this study was to gain insights about balance in the everyday lives of women with stress-related disorders. Data were gathered from 19 women who were past the first phase of recovery from a stress-related disorder and participated in one

Previous research has shown that judgments of learning (JOLs) made immediately after encoding have a low correlation with actual cued-recall performance, whereas the correlation is high for delayed,judgments. In this article, the authors propose a formal theory describing the stochastic drift of memory strength over the retention interval to account for the delayed-JOL effect. This is done by firs

Popular Abstract in Swedish För att kunna simulera de fysikaliska fenomen som pågår i förbränning, krävs även en beskrivning av den kinetik som ingår i förbränningsprocessen. För detta ändamål utvecklas kinetiska modeller. En kinetisk modell är en lista med kemiska reaktioner och reaktionshastighetsparametrar. Modellernas tillämpningsområde begränsas av de valideringsfall och de fysikaliska parameThe simulation of physical phenomena occurring in chemical reactors requires the description of the kinetics involved in the underlying combustion process. Kinetic models are developed for this purpose. A software package, BlueBellMouse, has been developed to facilitate a deeper automatization and ease of simulation, reduction and optimization of kinetic models. A kinetic model is made of a list o

We show that Calogero-Sutherland models for interacting particles have a natural supersymmetric extension. For the construction, we use Jacobians that appear in certain superspaces. Some of the resulting Hamiltonians have a direct interpretation as models for two kinds of interacting particles. One model may serve to describe interacting electrons in a lower and upper band of a one-dimensional sem

AIMS: Increased or altered activities of cysteine proteases have been implicated in serious human disorders such as cancer, rheumatoid arthritis, sepsis, and osteoporosis. To improve the current knowledge of the regulatory role of a major mammalian cysteine protease inhibitor, cystatin C, in such disease processes, a cystatin C deficient mouse was generated and characterized. METHODS: The mouse cy