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Creativity is a principal force of cognitive and communicational genesis that causes alteration of established rules and concepts (Heine/Kuteva 2007) and transgression of cultural borders (Lotman 1990). Artistic activity is normally taken for granted as creative, despite the fact that much artistic intention, is not necessarily aspiring to make any radical change of the circumstances in which it i
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The emancipatory appropriation of space, in the sense making personal adjustments and manoeuvres in order to raise a sense of space, can be understood in terms of giving and taking form, or what Catherine Malabou calls “plasticity”. Spatial production is in this sense defined relationally and cannot be fully provided by programmed architectural functions. That kind of relational and emancipatory vThe emancipatory appropriation of space, in the sense making personal adjustments and manoeuvres in order to raise a sense of space, can be understood in terms of giving and taking form, or what Catherine Malabou calls “plasticity”. Spatial production is in this sense defined relationally and cannot be fully provided by programmed architectural functions. That kind of relational and emancipatory v
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The borehole thermal resistance is both an important design parameter and a key performance characteristic of a borehole heat exchanger. Another quantity that is particularly important for deep borehole heat exchangers is the internal thermal resistance between the upward-flowing and downward-flowing fluid channels in the borehole. The multipole method is a well-known and robust method to compute
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Recent studies have shown that UVB irradiation induces primary and secondary hyperalgesia in rats and humans peaking about 24 h after UVB exposure. In the present study we investigated the changes in galanin, substance P and c-fos immunoreactivity in rat DRG and spinal cord at the L5 level 2–96 h after UVB irradiation. UVB irradiation of the heel area in rats almost increased the skin blood flow t
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Protein–protein interactions play important roles in bacterial pathogenesis. Surface-bound or secreted bacterial proteins are key in mediating bacterial virulence. Thus, these factors are of high importance to study in order to elucidate the molecular mechanisms behind bacterial pathogenesis. Here, we present a protein-based strategy that can be used to identify and isolate bacterial proteins of i
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The dopamine (DA) precursor, 3,4-dihydroxyphenyl-L-alanine (L-DOPA), is the most effective treatment for Parkinson's disease (PD), but causes dyskinesias (abnormal involuntary movements) in the vast majority of patients. There is a wide consensus that L-DOPA-induced dyskinesia (LID) depends on both pre- and postsynaptic disturbances of the nigrostriatal DA transmission. Presynaptically, LID is ass
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The purpose of this book chapter is to give the reader a thorough background to the fundamentals and applications of pressurized hot water extraction (PHWE) for the analysis of bioactive compounds. The chapter summarizes the field for 2009-2014 and includes fundamentals of water as a solvent; equipment; method optimization; a few selected applications; hyphenations and future aspects. It is highli
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The durability of wood depends on its in-use environmental conditions. The aim of the present study was to estimate the effects associated with macro climate and detail design as well as their interdependence. A numerical moisture model and two different decay prediction models were utilized for assessing the decay risk of a horizontal member and a joint exposed at 300 sites scattered across EuropThe durability of wood depends on its in-use environmental conditions. The aim of this study was to estimate the effects associated with macro climate and detail design as well as their interdependence. A numerical moisture model and two different decay prediction models were utilized for assessing the decay risk of a horizontal member and a joint exposed at 300 sites scattered across Europe. In g
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Since the earliest economic historical studies wage series have been used to sketch economic development both at the macro and the household level. This dissertation takes advantage of new data from women and men, working in both the countryside and in towns, as well as employed both by the day and on long-term contracts, in order to make an in-depth quantitative look at the relationships between
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När artificiell intelligens blir vardagligt applicerad i samhället – på konsumentmarknader, i sjukvården, trafiken och på digitala plattformar – väcks helt avgörande frågor kring hur ansvar bör fördelas och vilka normer som bör styra. I ljuset av AI som en lärande teknologi som interagerar med människor och sociala strukturer blir det också centralt att förstå vilka normer och värderingar som repr
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There is a growing body of evidence suggesting that individuals with obsessive-compulsive disorder (OCD) may be sub-typed along different symptom dimensions. These dimensions may help explain responsiveness to current treatments. The Dimensional Yale-Brown Obsessive-Compulsive Scale (DY-BOCS) is a validated instrument involving a self-report screening tool followed by a structured interview in whi
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Distributed solar photovoltaic systems are considered an important renewable energy source for meeting renewable energy targets and mitigating climate change. In several markets, emerging firms have established new business models to offer residential customers solar panel systems. In California, the third-party ownership business model has been successfully established during the last decade, and
