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In modern society with its ever-increasing interconnectedness and digitalisation, cybersecurity becomes a prominent issue with tangible ramifications beyond the cyber space. To effectively counter attacks, organisations and their cybersecurity managers must anticipate potential adverse events. Most public research in cybersecurity is concentrated on technology; however, some literature suggests t
Context Although prototyping is widely utilized in product and user interface design, as well as in requirements engineering practices within agile development, there exists a lack of theoretical frameworks surrounding this methodology. Aims The primary objective of this study is to explore both the benefits and costs of employing different types of prototyping with different levels of complexity
Byggnader är en central komponent i 3D stadsmodeller. Att skapa sådana modeller enligt relevant standard är inte alltid enkelt och kan vara tidskrävande. Den här studien undersöker en metod att skapa byggnadsmodeller utifrån the svenska nationella specifikationen (NS) för byggnader, i en detaljnivå (LOD) som inkluderar takform. Metoden utvärderar hur byggnadsytor (registerbyggnad) tillsammans med Buildings are a central component of three-dimensional (3D) city models. Generating such models according to an appropriate standard is not always straightforward and can be time-consuming. This study explores a method for generating building models that comply with the Swedish national specification (NS) for buildings, at a level of detail (LOD) that includes roof structures. The method evaluates
Vad kan vi lära oss om gränser och migrationspolitik när vi betraktar dem ur perspektivet hos de samhällen som lever i gränsområdena – och genom mobilitetens teoretiska linser?Denna avhandling undersöker effekterna av EU's politik för gränsexternalisering på dem som påverkas mest av den, med fokus på de levda erfarenheterna hos senegalesiska samhällen runtom i Senegal. Genom omfattande etnografiskWhat do we learn about borders and migration policies when we examine them from the perspective of communities living in the borderlands, and through the theoretical lenses of mobility? This thesis explores the effects of EU border externalisation policies on those most affected by them, focusing on the lived experiences of Senegalese communities throughout Senegal. Through extensive ethnographic
We present a novel method for in-line acoustofluidic separation of cancer cells directly from whole blood. We report for the first time the observation that blood cells can self-organize when packed closely together in an acoustic field. We utilize this effect to enrich K-562 cancer cells and white blood cell subpopulations from whole blood at normal hematocrit levels. Further, we investigate the
The Indian leopard is a species that frequently comes into conflict with humans due to their adaptability and wide habitat range, allowing them to persist around urban landscapes like Bengaluru. While the surrounding landscape naturally supports leopards, human factors have driven them to frequent urban areas. Increased leopard sightings have led to more translocations, but relocating animals base
Age-Friendly Cities and Communities (AFCC) is a key global WHO initiative aimed at fostering environments that promote healthy aging for everyone. As AFCC initiatives continue to expand, there is an increasing need to enhance monitoring and evaluation systems to effectively assess their progress and impact. However, significant knowledge gaps persist, particularly in the development of evaluation
Apolipoprotein E4 (ApoE4), the major genetic risk factor for Alzheimer's disease (AD), is vital for understanding cellular processes involved in AD pathogenesis. Evidence implicates endosomes as a central player in AD, where endosomal enlargement in neurons is among the earliest changes in AD. This enlargement was reported to be enhanced in APOE4 carriers. Cells internalize ApoE into endosomes for
MicroRNAs (miRNAs) are pivotal post-transcriptional regulators that orchestrate gene expression programs governing cancer initiation, progression, metastasis, and therapeutic resistance. Among their many targets, the WNT signaling pathway, a key driver of malignancy, is tightly controlled by miRNAs, forming intricate feedback loops that shape tumor behavior. Concurrently, flavonoids, naturally occ
Staphylococcus aureus remains one of the most elusive targets in bacterial vaccinology, primarily due to its complex immune evasion strategies and the phenomenon of immune imprinting. Despite decades of research and numerous clinical trials, no vaccine has demonstrated protective efficacy in humans. This review examines the underlying reasons for these failures and proposes a rational, integrativ
Gastrointestinal (GI) cancers, including esophageal, gastric, pancreatic, liver, and colorectal malignancies, represent a major global health burden due to their high incidence, aggressive nature, and limited treatment outcomes. This review explores the therapeutic potential of carvacrol, a naturally occurring monoterpenoid phenol predominantly found in oregano and other aromatic plants. Carvacrol
Industrial CO2 emissions, particularly from flue gases, are a major barrier to climate change mitigation. Carbon capture, particularly with bioenergy (BECCS), offers a pathway to negative emissions. This study models an MEA-based carbon capture system using operational data from a stand-alone pulp mill, focusing on its energy impact and optimization strategies. The analysis distinguishes between h
Additives such as binders and hydrophobic agents are commonly introduced into the fibrous Gas Diffusion Layer (GDL) of proton exchange membrane fuel cells to enhance mechanical strength and facilitate water management. However, the effect of additive/fiber content and surface wettability on water removal, oxygen diffusion, and heat conduction remains insufficiently understood. In this work, we dev
Type 1 diabetes, formerly known as juvenile diabetes or insulin-dependent diabetes, results from the specific autoimmune destruction of the pancreatic islet beta cells. The subsequent loss of insulin leads to increased blood and urine glucose. The classical symptoms are polyuria (frequent urination), polydipsia (increased thirst), polyphagia (increased hunger), and weight loss. The disease may be
Helsingborg has a strong trading heritage and a unique strategic location within the Nordic region. It's no coincidence that these factors have combined in the digital age to position Helsingborg as a key player in the world of e-commerce.The city's natural geographic advantages, alongside significant investments in infrastructure, have established a strong foundation for Helsingborg to become a l
Despite the multidimensionality of knowledge and technology transfer (KTT), existing quantitative evaluations predominantly focus on a limited range of channels, often resulting from the availability of data rather than theoretical considerations. To address this gap, we leverage unstructured data from university websites to develop indicators that provide a comprehensive view of universities’ KTT
The South African forestry supply chain is a complex system that involves both the production of trees (site preparation, re-establishment, tending, and maintenance operations) and the production and distribution of wood products from plantation stands to the pulp- and sawmills. This paper reports on a study that investigated the suitability of discrete-event simulation for modelling forestry supp
Dyes are routinely used in the textile and pharmaceutical industries, causing serious environmental issues by decreasing water quality. Photocatalysts are used for dye degradation, and different acting mechanisms may occur during the photodegradation process. In this study, Ni nanoparticles were heated to selected temperatures up to 500 °C under an ambient atmosphere and subsequently supported on
