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Cardiovascular effects of severe late-onset preeclampsia are reversed within six months postpartum

OBJECTIVES: Preeclampsia (PE) is a common pregnancy-related disorder associated with cardiovascular long-term disease. Eighty percent are late-onset PE, occurring after 34 gestational weeks, and can present with severe symptoms. Magnitude and reversibility rate of maternal cardiovascular changes after severe late-onset PE have not been characterized. This study therefore evaluated longitudinal dyn

Expression of HIF-1α is related to a poor prognosis and tamoxifen resistance in contralateral breast cancer

Background: Adjuvant endocrine treatment improves survival after estrogen receptor (ER) positive breast cancer. Recurrences occur, and most patients with metastatic breast cancer develop treatment resistance and incurable disease. An influential factor in relation to endocrine treatment resistance is tumor hypoxia and the hypoxia inducible transcription factors (HIFs). Poor perfusion makes tumors

We can only do it together: Addressing global sustainability challenges through a collaborative paradigm

Urgent structural change is required in higher education, to allow collaboration both within and across universities, so that achieving rapid sustainability transition can become not only the overarching but the main purpose of education, research and work in society. A review of the literature reveals that fragmentation caused by traditional hierarchical faculty and disciplinary organisation is a

Adaptation and mitigation strategies for Kurdistan

The Kurdish economy is today heavily dependent on hydrocarbons exports. Current trends are that hydrocarbons exporting and processing countries, as well as interest groups within these countries, are pushing to expand production and maximise profits while this is still possible. The magnitude and observed acceleration of the present climate emergency - with major impacts both in terms of loss of c

The Possibility of Developmental States in Africa

Since roughly the turn of the millennium, there has been a growing literature discussing the potential characteristics of African Developmental States—if they exists and in that case how they should be defined and exemplified. The basis for this literature has been the experience of the trajectory for sustained economic growth in Pacific Asia. But it has expanded into a broader discussion about th

Nanowire Tunnel FET with Simultaneously Reduced Subthermionic Subthreshold Swing and Off-Current due to Negative Capacitance and Voltage Pinning Effects

Nanowire tunnel field-effect transistors (TFETs) have been proposed as the most advanced one-dimensional (1D) devices that break the thermionic 60 mV/decade of the subthreshold swing (SS) of metal oxide semiconductor field-effect transistors (MOSFETs) by using quantum mechanical band-to-band tunneling and excellent electrostatic control. Meanwhile, negative capacitance (NC) of ferroelectrics has b

Proteomic profiles before and during weight loss : Results from randomized trial of dietary intervention

Inflammatory and cardiovascular biomarkers have been associated with obesity, but little is known about how they change upon dietary intervention and concomitant weight loss. Further, protein biomarkers might be useful for predicting weight loss in overweight and obese individuals. We performed secondary analyses in the Diet Intervention Examining The Factors Interacting with Treatment Success (DI

Psychometric properties of the Connor-Davidson Resilience Scale (CD-RISC) in a non-clinical population in Sweden

Background: The Connor-Davidson Resilience Scale (CD-RISC) is the most widely used scale which assesses psychological resilience. Although it is recommended to be applied as a unidimensional scale, its factor structure, reliability, as well as discriminant and predictive validity need to be assessed when used in a new context. Moreover, the original five-factor structure has not been replicated in