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Reduced cerebrospinal fluid level of thyroxine in patients with Alzheimer's disease
Background: Little is known of the association between thyroid hormones in the central nervous system and Alzheimer's disease (AD). We determined thyroid hormone levels in serum and cerebrospinal fluid (CSF) in a well-defined homogeneous mono-center population. Methods: Fifty-nine consecutive patients under primary evaluation for cognitive impairment were recruited. The participants included patie
A synthesis of cloud condensation nuclei counter (CCNC) measurements within the EUCAARI network
Cloud condensation nuclei counter (CCNC) measurements performed at 14 locations around the world within the European Integrated project on Aerosol Cloud Climate and Air Quality interactions (EUCAARI) framework have been analysed and discussed with respect to the cloud condensation nuclei (CCN) activation and hygroscopic properties of the atmospheric aerosol. The annual mean ratio of activated clou
Risk factor-based interventions or population-based smoking policy initiatives in tobacco smoking prevention? A reply to Najman (2013) concerning commentary on Lindström et al. (2013).
Opposite effects of learning cause asymmetric mate preferences in hybridizing species
How do females decide which males to accept or reject as potential mates when the individuals encountered are unfamiliar and may be either heterospecifics or conspecifics? Learning often influences the development of mate preferences. Experience with particular phenotypes often positively biases preference for that phenotype. However, experience can also induce aversion. We studied the effect of s
Functional performance in self-care and mobility after selective dorsal rhizotomy: a 10-year practice-based follow-up study.
To explore changes in performance in daily activities (self-care and mobility) 10 years after selective dorsal rhizotomy (SDR).
Lactobacillus apinorum sp. nov., Lactobacillus mellifer sp. nov., Lactobacillus mellis sp. nov., Lactobacillus melliventris sp. nov., Lactobacillus kimbladii sp. nov., Lactobacillus helsingborgensis sp. nov., and Lactobacillus kullabergensis sp. nov., isolated from the honey stomach of the honeybee Apis mellifera.
We discovered a symbiotic lactic acid bacterial (LAB) microbiota in the honey stomach of the honeybee Apis mellifera. The microbiota was composed of several phylotypes of Bifidobacterium and Lactobacillus. 16S ribosomal ribonucleic acid (rRNA) gene analyses and phenotypic and genetic characteristics revealed that the Lactobacillus phylotypes isolated represent seven novel species. One is grouped w
From Perspectives to Policy Contingencies: conditional cash transfers as social investments
Despite the popularity of the social investment approach, there remain ambiguities regarding how to design an effective social investment policy. We review evaluations of conditional cash transfers (CCTs) in Latin America in order to draw out lessons for how to improve the effectiveness of social investment. CCTs share many of the objectives of the social investment approach and are targeted at po
Determination of 21-hydroxylase autoantibodies: inter-laboratory concordance in the Euradrenal International Serum Exchange Program
Background: 21-Hydroxylase autoantibodies (21OHAb) are markers of an adrenal autoimmune process that identifies individuals with autoimmune Addison's disease (AAD). Quality and inter-laboratory agreement of various 21OHAb tests are incompletely known. The objective of the study was to determine inter-laboratory concordance for 21OHAb determinations. Methods: Sixty-nine sera from 51 patients with A
Carbon dioxide degassing in fresh and saline water I: degassing performance of a cascade column
A study was undertaken to measure carbon dioxide degassing in a cascade column operating with both fresh (0‰) and saline water (35‰ NaCl) at 15 ◦C. The cascade column contained bio-block type packing material, was 1.7m long in each dimension, and was tested both with and without countercurrent air exchange. The CO2 concentration of the influent and effluent water was measured using submersible inf
The Hlagothi Complex: The identification of fragments from a Mesoarchaean large igneous province on the Kaapvaal Craton
In this paper, we present geochronological, geochemical and palaeomagnetic results from the Hlagothi Complex and a NW-trending dolerite dyke swarm on the southeastern region of the Kaapvaal Craton in northern KwaZulu-Natal, South Africa. The Hlagothi Complex consists of layered sills of meta-peridotite, pyroxenite and gabbro intruding into the Pongola Supergroup. U-Pb baddeleyite ages on the Hlago
Stages of Change in Adults Who Have Failed an Online Hearing Screening.
Hearing screening has been proposed to promote help-seeking and rehabilitation in adults with hearing impairment. However, some longitudinal studies point to low help-seeking and subsequent rehabilitation after a failed hearing screening (positive screening result). Some barriers to help-seeking and rehabilitation could be intrinsic to the profiles and needs of people who have failed a hearing scr
Prognostication in comatose survivors of cardiac arrest: An advisory statement from the European Resuscitation Council and the European Society of Intensive Care Medicine.
To review and update the evidence on predictors of poor outcome (death, persistent vegetative state or severe neurological disability) in adult comatose survivors of cardiac arrest, either treated or not treated with controlled temperature, to identify knowledge gaps and to suggest a reliable prognostication strategy.
Chiral-symmetric technicolor with standard model Higgs boson
Most of the traditional technicolor-based models are known to be in a strong tension with the electroweak precision tests. We show that this serious issue is naturally cured in strongly coupled sectors with chiral-symmetric vectorlike gauge interactions in the framework of the gauged linear sigma model. We discuss possible phenomenological implications of such a nonstandard chiral-symmetric techni
In search of the force of dependent verb second
This short communication is a brief extension of recent work on verb second in Scandinavian declarative clauses and is a contribution to research on the relation between V2 and illocutionary force. It is argued that Swedish data present a problem for the hypothesis that a bi-conditional relation holds between the illocutionary force of an assertion and the verb second word order. The relevant forc
Modernity, Boredom and War: A Suggestive Essay
Clinical evaluation of a further developed Applanation Resonance Tonometer
Measurement of the production cross section of prompt j/psi mesons in association with a W (+/-) boson in pp collisions root s=7 TeV with the ATLAS detector
The process pp -> W (+/-) J/psi provides a powerful probe of the production mechanism of charmonium in hadronic collisions, and is also sensitive to multiple parton interactions in the colliding protons. Using the 2011 ATLAS dataset of 4.5 fb(-1) of root s= 7 TeV pp collisions at the LHC, the first observation is made of the production of W (+/-) + prompt J/psi events in hadronic collisions, using
Upper Limit of Cancer Extent on Biopsy Defining Very Low Risk Prostate Cancer.
To investigate how much Gleason pattern 3 cancer the prostate biopsy specimens may contain without an increased risk of undetected more aggressive cancer, compared with the risk for cancers fulfilling the National Comprehensive Cancer Network (NCCN) criteria for very low risk prostate cancer.
Hunting for Protein Markers of Hypoxia by Combining Plasma Membrane Enrichment with a New Approach to Membrane Protein Analysis
Nontransient hypoxia is strongly associated with malignant lesions, resulting in aggressive behavior and resistance to treatment. We present an analysis of mRNA and protein expression changes in neuroblastoma cell lines occurring upon the transition from normoxia to hypoxia. The correlation between mRNA and protein level changes was poor, although some known hypoxia-driven genes and proteins corre