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The use of diafiltration is now the state-of-the-art in the food and beverage, biotech and pharmaceutical industry. In this paper, the advantages and disadvantages of the most common process modes of diafiltration, batch and continuous, are discussed. Further, the new concept of counter-current diafiltration, which leads to a significant reduction of diafiltration liquid consumption, is introduced
In hydrophobic pervaporation, the evaluation and prediction of coupling effects in multicomponent systems is one of the key requirements to improve its applicability in the biotechnology and food industry. The focus of this study is first on binary aqueous systems with methanol, ethanol, acetone, 1-propanol, 2-propanol 1,3-dioxane, and 1,4-dioxane, and then on ternary aqueous systems with 1-propan
The different processes used for producing carrageenan, which is a sulfated polysaccharide consisting of complex mixture of sodium, potassium, magnesium, and calcium, are discussed. The sources of carrageenan are several genera and species of red algae. The traditional production process involves extraction with water and mechanical devices to remove most extraneous products. A new generation of s
Background: Porous metal augments have been used successfully for management of large acetabular defects during revision hip arthroplasty. The purpose of this study was to retrospectively review and compare the clinical and radiographic outcomes of porous metal augments in cemented and uncemented acetabular revisions, all performed at the same institution. Methods: Using our institutional clinical
Hydrophobic pervaporation is rarely considered in the biotech industry despite several potential advantages and some applications. This is related to fact that the majority of studies have been with binary feed systems, while real feed mixtures are often multi-component and might contain impermeable components, such as salts and sugars. In order to successfully optimise hydrophobic pervaporation,
Ultrafiltration with diafiltration is a state-of-the-art process used to separate solutions containing high and low molecular weight solutes. The focus of this paper is on the different concepts of ultrafiltration with diafiltration - batch, continuous and counter-current - and the potential realization of diafiltration on an industrial scale in pharmaceutical biotechnology. Two case studies will
Taste is the most important criteria in evaluating the quality of wine and beer. Alfa Laval's Frank Lipnizki, Carl-Erik Nielsen, Robert Betcke and Jose Caprio highlight the potential that membrane processes offer in maintaining and improving taste during production.
Membrane technology is a relative new technology in the pulp and paper industry with interesting applications in the water loop, the by-product loop and the chemical loop. The technology was pioneered in the pulp and paper industry by DDS Filtration, now Alfa Laval Nakskov in the 1970'ies and this article reviews the opportunities to use membrane technology in the different loops investigated over
Type 2 Diabetes (T2D) is a disease of increasing importance and represents a growing burden on global healthcare and human health. In T2D, loss of effectiveness of insulin signaling in peripheral tissues cannot be compensated for by adequate insulin secretion, leading to hyperglycemia and resultant complications. In recent years, inflammation has been identified as a central component of T2D, both
The use of cross-flow ultrafiltration for the recovery of coating material from aqueous streams started about 30 years ago with electro-deposition paint in the automotive industry. This early success can be related to both environmental and economical advantages of using ultrafiltration. Ultrafiltration recovers and concentrates electro-deposition paint on the retentate side and produces purified
Described is a method for preparing a purified liquid containing carbohydrates. The method comprises the steps of: hydrolysing starch to a dextrose equivalent (DE) of 10 or above, thus obtaining a liquid of carbohydrates; removing a heavy weight sludge fraction from the light weight liquid of carbohydrates using centrifugation; filtering the remaining liquid of carbohydrates, the filter being capa
An Eulerian Monte-Carlo approach, the so-called Eulerian stochastic fields (ESF) method is implemented and evaluated for simulation of non-premixed hydrogen/air combustion in supersonic flows. The ESF method is integrated into a compressible flow large eddy simulation (LES) solver, and validated on a supersonic combustor with a strut as flame-holder. Comparison with experimental data and with resu
Objective:This post-hoc analysis of the EDGE (Effectiveness of Diabetes control with vildaGliptin and vildagliptin/mEtformin) study assessed inter-regional differences in baseline characteristics and response to treatment intensification with dual oral antidiabetes drugs (OADs) in patients with type 2 diabetes mellitus (T2DM).Methods:Patients with T2DM inadequately controlled with first-line monot
Objective: The aim of this study was to create a preoperative prediction model predicting extraprostatic tumour growth in men with clinically organ-confined disease from a prospectively collected Swedish cohort. Materials and methods: The study used data from 3386 men in the prospective multi-centre Laparoscopic Prostatectomy Robot Open (LAPPRO) trial, with 14 participating urological departments.
We examined the association between unintentional nonhunting firearm deaths and changes in firearm legislation in Sweden. There were 43 fatalities during the study time frame 1983–2012, representing 46% of all unintentional firearm deaths during the same period. The victims were predominantly young males (mean age 25 years). Slightly more than half of the deaths were caused by another person and w
We describe a method and device (< 1.2 g) for recording, processing and storing data about activity and location of individuals of free-living songbirds throughout the annual cycle. Activity level was determined every five minutes from five 100 ms samples of accelerometer data with 5 s between the sampling events. Activity levels were stored on an hourly basis throughout the annual cycle, allowing
Time synchronization is crucial for wireless sensor networks (WSNs), where operations often rely on time ordering of events. WSNs are deployed in different scenarios, and therefore their timing requirements are often related to the peculiar characteristics of the specific environment they have to act in. Synchronization is anyway always an issue: transactional applications need monotonicity of the
