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Utilizing the excellent mass resolving power of SHIPTRAP and the charged-particle-g multicoincidence setup TASISpec, the decay path of the 213Ra ground state can be exclusively studied. Based on virtual experiments with Geant4 it is possible to refine the a-branching ratios of the 213Ra ground state as well as g-ray branching ratios in the 209Rn daughter. The present study provides a proof of conc
The 54Fe nucleus was populated from a 56Fe beam with an energy of E=A=500 MeV. The internal decay of the 10+ metastable state via g-ray emission was observed. The structure of this isomeric state has to involve at least four unpaired nucleons, therefore it cannot be populated in a simple two-neutron removal reaction from the ground state of 56Fe, and we suggest that it was populated via the decay
A series of racemic aryl-substituted phenylalanines was synthesized and evaluated in vitro at recombinant rat GluA1-3, at GluK1-3, and at native AMPA receptors. The individual enantiomers of two target compounds, (RS)-2-amino-3-(3,4-dichloro-5-(5-hydroxypyridin-3-yl)phenyl)propanoic acid 37 and (RS)-2-amino-3-(3'-hydroxybiphenyl-3-yl)propanoic acid 38, were characterized. (S)-37 and (R)-38 were id
The α4β2 subtype of the nicotinic acetylcholine receptor has been pursued as a drug target for treatment of psychiatric and neurodegenerative disorders and smoking cessation aids for decades. Still, a thorough understanding of structure-function relationships of α4β2 agonists is lacking. Using binding experiments, electrophysiology and x-ray crystallography we have investigated a consecutive serie
Positive allosteric modulators of the ionotropic glutamate receptor-2 (GluA2) are promising compounds for the treatment of cognitive disorders, e.g. Alzheimer's disease. These modulators bind within the dimer interface of the LBD (ligand-binding domain) and stabilize the agonist-bound conformation slowing receptor desensitization and/or deactivation. In the present study, we employ isothermal titr
Abstract: A measurement of the cross section for the inclusive production of isolated prompt photons in proton-proton collisions at a centre-of-mass energy of s=8 TeV is presented. The measurement covers the pseudorapidity ranges |ηγ | < 1.37 and 1.56 ≤ |ηγ | < 2.37 in the transverse energy range 25 < ET γ < 1500 GeV. The results are based on an integrated luminosity of 20.2 fb−1, recorded by the
A search for singly produced vector-like Q quarks, where Q can be either a T quark with charge + 2 / 3 or a Y quark with charge - 4 / 3 , is performed in proton–proton collisions recorded with the ATLAS detector at the LHC. The dataset corresponds to an integrated luminosity of 20.3 fb- 1 and was produced with a centre-of-mass energy of s=8 TeV. This analysis targets Q→ Wb decays where the W boson
This paper presents a measurement of the double-differential cross section for the Drell-Yan Z/γ∗ → ℓ+ℓ− and photon-induced γγ → ℓ+ℓ− processes where ℓ is an electron or muon. The measurement is performed for invariant masses of the lepton pairs, mℓℓ, between 116 GeV and 1500 GeV using a sample of 20.3 fb−1 of pp collisions data at centre-of-mass energy of s=8 TeV collected by the ATLAS detector a
This paper describes a measurement of fiducial and differential cross sections of gluon-fusion Higgs boson production in the H → W W∗→ eνμν channel, using 20.3 fb−1 of proton-proton collision data. The data were produced at a centre-of-mass energy of s=8 TeV at the CERN Large Hadron Collider and recorded by the ATLAS detector in 2012. Cross sections are measured from the observed H→ W W∗→ eνμν sig
WNT5A is a secreted signaling protein that promotes migration and invasion of oral squamous cell carcinoma (OSCC) cells through activation of non-canonical WNT signaling. Here, we examined expression of WNT5A, β-catenin, and E-cadherin by immunohistochemistry in 21 human diagnostic incision biopsies that each had regions of oral mucosa with a normal appearance adjacent to the affected tissue, dysp
A search for supersymmetry in events with large missing transverse momentum, jets, and at least one hadronically decaying tau lepton has been performed using 3.2 fb-1 of proton–proton collision data at s=13TeV recorded by the ATLAS detector at the Large Hadron Collider in 2015. Two exclusive final states are considered, with either exactly one or at least two tau leptons. No excess over the Standa
Mercury is a severe pollutant in China. A novel mobile laser spectroscopy laboratory was constructed and used in differential absorption lidar mapping in major Chinese cities, a heavily polluted mining area and an archeological site.
Heterogeneous catalysts for selective oxidation of C-H bonds were synthesized by co-polymerization of new N-heterocyclic carbene-palladium(II) (NHC-PdII) monomers with divinylbenzene. The polymer-supported NHC-PdII-catalysed undirected C-H acetoxylation of simple and methylated arenes as well as polyarenes, with similar or superior efficiency compared to their homogeneous analogues. In particular,
This book probes the relationship between Martin Heidegger and theology in light of the discovery of his Black Notebooks, which reveal that his privately held Antisemitism and anti-Christian sentiments were profoundly intertwined with his philosophical ideas. Heidegger himself was deeply influenced by both Catholic and Protestant theology. This prompts the question as to what extent Christian anti
