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The Polycomb complex protein Bmi1 is regarded as a master regulator of hematopoietic stem cells (HSCs). In the blood system, HSCs express Bmi1 most abundantly and Bmi1 expression vanes as cells differentiate. Furthermore, Bmi1 has been found overexpressed in several hematologic cancers. Most studies exploring the normal role of Bmi1 in HSC biology have utilized loss-of-function models, which have
INTRODUCTION: Childbirth is a life-changing event where fathers desire being involved. As fathers take a more active role, fear of childbirth can arise. The aim of this study was to explore fathers' experiences of childbirth fear during pregnancy and after the birth of their baby.METHODS: This was a qualitative longitudinal prospective study that included 14 interviews with seven fathers, one duri
Introduction:The timing of cord clamping impacts children’s short- and longterm well-being. When making clinical decisions, midwives incorporate their tacit and professional knowledge, experience and current evidence. There appears to be a lack of knowledge regarding Swedish midwives’ management of the third stage of labor and cord clamping practice. The aim of this study was to explore Swedish mi
Background:The goal of postnatal care is to provide the highest possible quality of care and medical safety with the least possibleintervention in order to optimize health and wellbeing of the new family. The aim of the study was to describemothers´ experiences in relation to a new postnatal home-based model of midwifery care.Method:Prospective cross sectional study based on quantitative and quali
Genom att ställa hälso- och sjukvårdskuratorns uppdrag i relation till det som feministiska och marxistiska forskare kallat ”vårdens moraliska ekonomi” bidrar artikeln till att fördjupa förståelsen av kuratorns betydelse i samhällets reproduktiva sfär. Begreppet ”vårdens moraliska ekonomi” syftar på de ”bindningar och skyldigheter” som mer än själva anställningskontraktet formar de vårdande profes
The delay or refusal of vaccination, which defines vaccine hesitancy, is a major challenge to successful control of COVID-19 epidemic. The huge number of publications addressing COVID-19 vaccine hesitancy necessitates periodic review to provide a concise summary of COVID-19 vaccine acceptance rates worldwide. In the current narrative review, data on COVID-19 vaccine acceptance rates were retrieved
This paper will report on four machine translation projects dealing with restricted domains and controlled or semi-controlled language. The computer program Seatra translates marine forecasts between Swedish and English. It is in daily use by the Swedish meteorological agency (SMHI) and generally needs no postediting. The same basic program but with different lexicons is used in the program Maltra
Alkaline membrane fuel cells can operate using nonprecious metals as catalysts, but rely on polymeric membranes with high hydroxide conductivity and alkali-resistance, which are hard to find. A new membrane is now reported comprising ferrocenium cations in magnetically aligned domains with an excellent combination of these properties.
Background: It is a critical challenge to diagnose leptomeningeal metastasis (LM), given its technical difficulty and the lack of typical symptoms. The existing gold standard of diagnosing LM is to use positive cerebrospinal fluid (CSF) cytology, which consumes significantly more time to classify cells under a microscope.Objective: This study aims to establish a deep learning model to classify can
Animals normally vocalise while exhaling. Ingressive, or inspiratory, voice production occurs in humans and many other species, but its communicative function, if any, remains unknown. To test the perceptual effects of ingressive phonation, naturally occurring ingressive syllables in 109 human nonverbal vocalisations (55 laughs, 21 cries, and 33 moans) were experimentally attenuated or morphed int
During the 2022 Winter Paralympic Games in Beijing, the Para snow-sport events will be held at high altitudes and in possibly cold conditions while also requiring adjustment to several time zones. Furthermore, the ongoing COVID-19 pandemic may lead to suboptimal preparations. Another concern is the high rate of injuries that have been reported in the Para alpine and snowboard events. In addition t
This report presents the findings from a pre-study concerning the opportunities and challenges of digitalization and automation in bridge design. The project approach is divided into three parts: 1) a short review of the relevant literature, 2) investigations concerning bridge industry perspectives (with focus on bridge consultants), and 3) the identification of future research needs based on part
Neutrophils are commonly regarded as the first line of immune response during infection or in tissue injury-induced inflammation. The rapid influx of these cells results in the release of host defense proteins (HDPs) or formation of neutrophil extracellular traps (NETs). As a second wave during inflammation or infection, circulating monocytes arrive at the site. Earlier studies showed that HDPs LL
