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The aim of this study was to evaluate the effects of vitamin K1 on various vitamin K-dependent proteins in critically ill patients with prolonged Owren PT. We included critically ill non-bleeding adult patients without liver failure or anticoagulation treatment, with Owren PT > 1.2, who were prescribed intravenous vitamin K1. Blood was drawn at baseline and at 20–28 h after vitamin K1 administratiThe aim of this study was to evaluate the effects of vitamin K1 on various vitamin K-dependent proteins in critically ill patients with prolonged Owren PT. We included critically ill non-bleeding adult patients without liver failure or anticoagulation treatment, with Owren PT > 1.2, who were prescribed intravenous vitamin K1. Blood was drawn at baseline and at 20–28 h after vitamin K1 administrati

Non-exhaust emissions, generated by the wear of brake systems, tires, roads, clutches, and road resuspension, are responsible for a large part of airborne pollutants in urban areas. Brake wear accounts for 55% of non-exhaust emissions and significantly contributes to urban health diseases related to air pollution. A major part of the studies reported in the scientific literature are focused on exp

The emergence of fourth-generation synchrotrons is prompting the development of new systems for experimental control and data acquisition. However, as general control systems are designed to cover a wide set of instruments and techniques, they tend to become large and complicated, at the cost of experimental flexibility. Here we present Contrast, a simple Python framework for interacting with beam

Although findings yield differing conclusions, there is a consensus that the US political system has polarized in the last few decades (Mason 2018). Outside of the US, empirical results have been scarce and mixed. Political polarization tends to be easier to measure in a two-party system, whereas multiparty systems might not be as conducive to clear cases of polarization. Media effects are one of

Achieving a more circular production and consumption pattern will require consumers to make proactive choices regarding practices such as repair and product life extension. However, galvanizing such choices and practices may not be left alone up to consumers because their behaviors are driven not only by internal factors (e.g., attitude and motivation), but also by external (e.g., economic, social

Research into repair within the circular economy (CE) typically focuses on technical aspects of design, policy, and markets, and often assumes or implies simplified conditions for the user/owner and the product-system to explain the barriers to scaling repair activities. By integrating life cycle and temporal dimensions (time-sequence) into a broad System of Repairability framework, we demonstrate

The European Commission describes a Circular Economy (CE) as an economy “where the value of products,materials and resources is maintained in the economy for as long as possible, and the generation of waste minimised.”But what is value in this context and how should CE policies consider value? Extended producer responsibility(EPR) policies are an important part of an EU CE Action Plan. However, th

Gait disorders are a relevant factor for falls and possible to measure with wearable devices. If a wearable sensor can detect differences in gait parameters between fallers and non-fallers has not yet been studied. The aim of this study was to measure and compare gait parameters, vestibular function, and balance performance between fallers and non-fallers among a group of older persons. Participan

OBJECTIVES: Son preference and sex selective practices have resulted in a deficit of girls in several countries, primarily across Asia. Emerging evidence indicates that son preference survives migration to Western high-income countries. The objective of this study was to assess male-to-female (M/F) ratios at birth per mother's country of birth in Australia 1997-2016, in total and by parity, and by

In the context of the Circular Economy, there is a lot of discussion on how policies at European Union and member state levels could provide incentives for the design of more durable products. One potential policy approach is to mandate manufacturers to provide lifetime information to consumers at the time of purchase. This could be done through a specific labeling scheme, or by including such inf

Ecodesign policy for energy-using products so far has tended to focus on the energy efficiency requirements, but there is increasing interest in durability requirements as well. This exploratory study analyses whether and when long lifetimes are preferable when considering the trade-offs between durability and other important parameters such as costs and environmental impacts, examining the case o