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A C3-symmetric macrocycle with alternating sugar amino acid and tyrosine residues was synthesized in seven steps from tyrosine tert-butyl ester and a sugar amino acid precursor derived from D-glucosamine. An Fmoc-protected D-glucosamine derivative was oxidized at C-6 to give the sugar amino acid, which was immediately coupled to tyrosine tert-butyl ester to produce an orthogonally protected buildi
Including a reactive settler model in a wastewater treatment plant model allows representation of the biological reactions taking place in the sludge blanket in the settler, something that is neglected in many simulation studies. The idea of including a reactive settler model is investigated for an ASM1 case study. Simulations with a whole plant model including the non-reactive Takacs settler mode
1. Adrenaline-stimulated lipolysis in adipose tissue may increase with training. The rate-limiting step in adipose tissue lipolysis is catalysed by the enzyme hormone-sensitive lipase (HSL). We studied the effect of exercise training on the activity of the total and the activated form of HSL, referred to as HSL (DG) and HSL (TG), respectively, and on the concentration of HSL protein in retroperito
Hadronic events from the data collected with the DELPHI detector at LEP within the energy range from 89 GeV to 209 GeV are selected, their jet rates are determined and compared to predictions of four different event generators. One of them is the recently developed APACIC++ generator which performs a massive matrix element calculation matched to a parton shower followed by string fragmentation. Th
An experiment was performed with the Gammasphere Ge-detector array, and the Microball charged particle detector, to search for transitions involved in the decay from the yrast superdeformed band in Eu-143. Sum spectra in coincidence with single, double, and triple gates on SD transitions were produced to search for previously reported two-step links between the superdeformed and the near-yrast ND
How do we, in a basic statistics course, create a learning environment where the computer is a natural tool? Different aspects to be considered are the students' feeling of ownership and the importance of integrating the computer exercises in the course syllabus. The teacher has different tools to achieve a computer-supported learning environment and we give some examples. The actual design of the
The title compound, 2,6-bis(5,6-dicyclohexyl-1,2,4-triazin-3-yl) pyridine, C35H57N7.CH2Cl2.0.625H(2)O, crystallizes with two molecules in the asymmetric unit, along with 1.25 molecules of water and two molecules of dichloromethane. The water molecules are involved in hydrogen-bond interactions with some N atoms of the triazine rings.
In order to study the body size of wild boar Sits scrofa Linnaeus, 1758 during the Boreal and Atlantic Chronozones in southern Scandinavia, 12 measurements of teeth and bones from 32 Mesolithic sites from Scania (Sweden) and Zealand and Jutland (Denmark) were analysed. The osteometric analysis revealed that the body size of wild boar from Scania did not change during the period. The results indica
Gold (Au) and platinum (Pt) screen-printed electrodes were modified with Prussian Blue (PB) for the development of amperometric sensors selective for hydrogen peroxide detection. The sensors exhibited sensitivities towards H2O2 equal to 2 A M−1 cm−2 for Au and 1 A M−1 cm−2 for Pt electrodes. The sensors were also employed as the basis for construction of glucose biosensors through further modifica
A key fatty acid synthesis enzyme, acetyl-CoA carboxylase alpha(ACC-alpha), has been shown to be highly expressed in human breast cancer and other tumor types and also to specifically interact with the protein coded by one of two major breast cancer susceptibility genes BRCA1. We used a comprehensive haplotype analysis to examine the contribution of the ACC-alpha common genetic variation (allele f
Both glomerular and tubular markers have been used to follow diabetic nephropathy. However, neither albumin nor proximal tubular markers have proven useful in prepubertal diabetes. Hence we studied two markers derived from the distal tubular cells, Tamm-Horsfall protein (THP) and epidermal growth factor (EGF), The urinary excretion of THP and EGF was examined in samples obtained during the first 2
Background: Deinstitutionalisation has led to many people with serious mental illness spending most of their time outside psychiatric institutions. Not much is known about their subjective life. The paper presents the results of analysis of self-esteem in a group of non-institutionalised people with schizophrenia. Methods: Interviews were conducted with random samples of people with schizophrenia
