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Background: The difficulty of determining the prognosis for the individual patient with invasive bladder cancer is a major clinical problem. Currently, decisions regarding therapy are mainly based on tumour stage and grade, the first of which is notoriously demanding to ascertain. New molecular markers are however proposed to be of prognostic value. At present, there is considerable debate regardi
Popular Abstract in Swedish Papperstillverkning inkluderar flera processteg såsom flisning av träråvaran, massakokning och avvattning med vakuumlådor, pressning och torkning. Flera modeller av de mest viktiga processerna i torkpartiet presenteras i denna avhandling. Modellerna beskriver både statiska och dynamiska förlopp. Nya reglerstrategier som kan användas för både reglering vid stationär drifThe paper making process involves chopping of wood, cooking and forming, followed by dewatering in a vacuum section, press section and drying section. Several models for the most important parts of the paper machine drying section are presented in this thesis to describe phenomena at steady state and during state transitions. New control strategies applicable/useful for both steady-state control a
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Long term evaluation of an asymmetric CPC PV-thermal hybrid built for high latitudes, MaRcCo (MaximumReflectorCollector), is performed in Lund, lat 55.7 degrees, and this paper discusses output estimates and characteristics of the system. The output estimates are calculated using the MINSUN simulation program. To get the input for MINSUN, measurements were performed on two MaReCo prototypes. These
Improvement of road traffic safety is an important policy issue. Various categories of meas-ures are available to effectuate this. The thesis focuses on two categories: road infrastructure and driv-ing assistance systems. A relevant policy question is if certain driving assistance systems may be de-sirable substitutes for infrastructure measures, in terms of traffic safety effects and other releva
The regulation of phospholipase D was studied in human neuroblastoma cells using phosphatidylethanol as a marker of the enzyme activity. Carbachol induced phospholipase D activity in SH-SY5Y cells. Muscarinic antagonists inhibited the response with potencies suggesting that muscarinic M1 receptors are responsible for the activation. In permeabilized SH-SY5Y cells, both the carbachol- and GTP gamma
Öresund is one of the areas in the world with most ship movements. More than 40,000 ships pass through the sound in the direction north-south or the opposite every year. Other ships/ferries frequently cross the sound in the direction east-west or west-east. The ships carry goods and/or passengers in huge volumes. Since Öresund is a quite narrow sound with a difficult navigation situation, many ris
PIP: The aim of this study was to define epidemiologic and psychosocial characteristics of women with a history of casual travel sex abroad. The participants were 996 women seeking contraceptive advice, of whom 276 admitted that they had experienced casual travel sex. The remaining women served as a comparison group. In structured interviews, questions were asked about educational level, partnersh
Popular Abstract in Swedish Området runt Forsmarks kärnkraftverk i Östhammars kommun, ca 80 km norr om Uppsala, valdes år 2000 ut som en av två möjliga kandidater för byggandet av ett slutförvar för använt kärnbränsle. År 2002 startade SKB (Svensk Kärnbränslehantering AB) en platsundersökning i området, vars syfte bland annat är att samla in tillräckligt mycket kunskap om berget och dess egenskapeThe Forsmark area, in the western part of the Svecofennian orogen, central Sweden, is situated between two major Palaeoproterozoic tectonic domains that show contrasting histories with respect to timing of igneous activity, ductile deformation and metamorphism. At Forsmark, WNW to NW trending, ductile deformation belts anastomose around tectonic lenses with an inferred lower degree of ductile stra
The importance of screening programs in reducing the prevalence of genital chlamydial infections is stressed by the fact that the majority of infected persons are more or less asymptomatic. The use of oral contraceptives may mask infections affecting the upper genital tract. This imposes selective screening and rescreening of women with a history of pelvic inflammatory disease. The recent knowledg
This paper presents theory for stability analysis and design for a class of observer-based feedback control systems. Relaxation of the controllability and observability conditions imposed in the Yakubovich-Kalman-Popov (YKP) lemma can be made for a class of nonlinear systems described by a linear time-invariant system (LTI) with a feedback-connected cone-bounded nonlinear element. It is shown how
AIM: To study the interaction between the human cysteine proteinase inhibitor, cystatin C, and proteinases of periodontitis associated bacteria. METHODS: Gingival crevicular fluid samples were collected from discrete periodontitis sites and their cystatin C content was estimated by enzyme linked immunosorbent assay (ELISA). The interaction between cystatin C and proteolytic enzymes from cultured s
Research has been done on children’s participation in review meetings, a method for reviewing foster and residential care. The method is tested within the national project Children’s Needs in Focus (BBIC) inspired by the British Integrated Children’s System and operated by the National Board of Health and Welfare (Socialstyrelsen) in Sweden. The objective of the evaluation, conducted on behalf of
Background Sick leave due to neck, shoulder and back disorders (NSBD) is higher among health-care workers, especially nursing aides/assistant nurses, compared with employees in other occupations. More information is needed about predictors of sick leave among health care workers. The aim of the study was to assess whether self-reported factors related to health, work and leisure time could predict
The spatial distribution of genetic markers can be useful both in estimating patterns of gene flow and in reconstructing biogeographic history, particularly when gene genealogies can be estimated. Genealogies based on nonrecombining genetic units such as mitochondrial and chloroplast DNA often consist of geographically separated clades that come into contact in narrow regions. Such phylogeographic
