The analysis departs from the FCC’s stringent proportionality review to elaborate an argument on what intensity of review should be adopted when reviewing the ECB’s economic policies. Building on previous scholarly analyses (Öberg) and relevant Court case law( Spain v Council and Vodafone,) it suggests that the proper standard of proportionality analysis should primarily be guided by the nature of

Lignin is the second most abundant biopolymer in nature and a promising renewable resource for aromatic chemicals. For the understanding of different lignin isolation and conversion processes, the identification of phenolic compounds is of importance. However, due to the vast number of possible chemical transformations, the prediction of produced phenolic structures is challenging, and a non-targe

After the fall of the Berlin wall and the end of the Cold War, a certain sense of optimism swept across Europe. Some 25 years later, everything seems radically different. With the considerable inroads made into mainstream politics by right-wing populist parties across the continent, there is no shortage of gloom and worry. Nevertheless, despite numerous examples of retrogressive forms of mobilizat

This paper proposes a relational time-geography approach to differentiate the geographies of recreational activities, whose place cannot be pinned down to a single specific infrastructure or area and therefore risks being marginalised in planning. Running is used as a case study. Based on diary-interviews, we have identified three different exercises/places used alternately by the respondents: the

This contribution examines, in the Central and Eastern European context, the interplay between ideals of national specificity, welfare chauvinist appeals, and emerging politics of migration, for the purpose of providing welfare provision to a narrowly defined ethnic group, as promoted by right-wing populist parties in the region. We suggest a comparative framework to account the various positions

Geospatial information plays an indispensable role in various interdisciplinary and spatially informed analyses. However, the use of geospatial information often entails many semantic intricacies relating to, among other issues, data integration and visualization. For the integration of data from different domains, merely using ontologies is inadequate for handling subtle and complex semantic rela

In this study, Spatial Multi-Criteria Evaluation and the least cost path analysis were applied to find the optimal by-pass road alignment in the Tlokweng Planning Area in Botswana. One-At-a-Time sensitivity analysis and the statistical test for zero proportion were used to investigate the robustness of the entire model. Four alternative by-pass roads were produced stressing economic, environmental

We present the widespread Ewald summation method in a new light by utilizing a truncated Gaussian screening charge distribution. This choice entails an exact formalism, also as particle mesh Ewald, which in practice is not always the case when using a Gaussian screening function. The presented approach reduces the number of dependent parameters compared to a Gaussian and, for an infinite reciproca

Swelling of the brain or spinal cord (CNS edema) affects millions of people every year. All potential pharmacological interventions have failed in clinical trials, meaning that symptom management is the only treatment option. The water channel protein aquaporin-4 (AQP4) is expressed in astrocytes and mediates water flux across the blood-brain and blood-spinal cord barriers. Here we show that AQP4

Importance: The diagnostic performance of second-generation tau positron emission tomographic (PET) tracers is not yet known. Objective: To examine the novel tau PET tracer RO948 F 18 ([18F]RO948) performance in discriminating Alzheimer disease (AD) from non-AD neurodegenerative disorders. Design, Setting, and Participants: In this diagnostic study, 613 participants in the Swedish BioFINDER-2 stud

In Sweden the responsibility for environmental damage when emergency responders are called to an incident is increasingly focussing on the responders. The problem is that most incident response personnel do not have the training and expertise to assess the environmental consequences of their suppression operations. The Fire Impact Tool was developed for training responders about how fire effluents

Aims: Hypertension is the leading cause for the development of heart failure (HF). Here, we aimed to identify cardiomyocyte stretch-induced circulating biomarkers for predicting hypertension-associated HF. Methods and results: Circulating levels of 149 proteins were measured by proximity extension assay at baseline examination in 4742 individuals from the Malmö Diet and Cancer study. Protein level