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Half-Life Systematics across the N=126 Shell Closure: Role of First-Forbidden Transitions in the β Decay of Heavy Neutron-Rich Nuclei.

This Letter reports on a systematic study of β-decay half-lives of neutron-rich nuclei around doubly magic ^{208}Pb. The lifetimes of the 126-neutron shell isotone ^{204}Pt and the neighboring ^{200-202}Ir, ^{203}Pt, ^{204}Au are presented together with other 19 half-lives measured during the "stopped beam" campaign of the rare isotope investigations at GSI collaboration. The results constrain the

Hidden exposure to formaldehyde in a swab caused allergic contact dermatitis

Octocrylene is an ultraviolet (UV)B and UVAII absorber that was introduced some 15 years ago, and is now widely used in sunscreen agents and skin care cosmetics. Since 2003, several studies, notably from France, Belgium, Spain, and Italy, have reported an increasing number of patients with photocontact allergy to octocrylene. This reaction is seen mainly in adult patients who have previously used

Acute Achilles Tendon Rupture A Questionnaire Follow-up of 487 Patients

BACKGROUND: The optimum treatment of acute total Achilles tendon rupture remains controversial. In the present study, the outcomes of surgical and nonsurgical treatment in a large number of patients were compared on the basis of patient age and sex. METHODS: The records of all 487 patients with an acute total Achilles tendon rupture that had occurred between 2002 and 2006 and had been treated at

Regulation of vascular endothelial growth factor (VEGF) in prostate cancer.

Prostate cancer (PCa) is the most common malignancy affecting men in the western world. While radical prostatectomy and radiation therapy can successfully treat a majority of patients, up to ~30% will experience local recurrence or metastatic disease. Prostate carcinogenesis and progression is typically an androgen dependent process. For this reason, therapies for recurrent PCa target androgen bio

Swedish birds are tracking temperature but not rainfall: evidence from a decade of abundance changes

Aim: To quantify avian distribution shifts and the extent of niche tracking in response to changing temperature and precipitation patterns. Location: Sweden. Methods: We used abundance monitoring data to quantify changes in bird species distributions between two time periods, 2000-02 and 2010-12. First we examined shifts at the level of whole distributions using population centroids in temperature

Rituximab and abatacept but not tocilizumab impair antibody response to pneumococcal conjugate vaccine in patients with rheumatoid arthritis

Introduction: The objective of the study was to investigate the impact of newer biologic treatments including rituximab, abatacept and tocilizumab on antibody response following pneumococcal vaccination using a 7-valent conjugate vaccine in patients with established rheumatoid arthritis (RA). Methods: Patients with RA receiving rituximab, abatacept or tocilizumab as monotherapy or combined with me

High methane yields and stable operation during anaerobic digestion of nutrient-supplemented energy crop mixtures

The feasibility of digesting energy crops supplemented with macro- and micronutrients instead of manure, without the commonly applied long hydraulic retention time (HRT), was investigated in long-term, single-stage continuous stirred tank processes. The crops used were mixtures of sugar beets, maize and whole crop triticale. The organic loading rate (OLR) measured as a total solid (TS) was 1.5-5.5

An Empirical Investigation of Efficiency and Price Uniformity in Competing Auctions

Abstract in Undetermined This paper investigates hypotheses related to efficiency and price uniformity in online competing auctions based on two theoretical predictions from Peters and Severinov [Peters, M., Severinov, S., 2006. Internet auctions with many traders. Journal of Economic Theory 130, 220–245]. The investigation is conducted using a large and ideal data set for online competing train t

High glucose enhances store-operated calcium entry by upregulating ORAI/STIM via calcineurin-NFAT signalling

ORAI and stromal interaction molecule (STIM) are storeoperated channel molecules that play essential roles in human physiology through a coupling mechanism of internal Ca2+ store to Ca2+ influx. However, the roles of ORAI and STIMin vascular endothelial cells under diabetic conditions remain unknown. Here, we investigated expression and signalling pathways of ORAI and STIM regulated by high glucos

Youth, Sexual Risk-Taking Behavior, and Mental Health: a Study of University Students in Uganda.

BACKGROUND: Little focus has been paid to the role of mental health among young people with regard to risky sexual behavior and HIV prevention in sub-Saharan Africa. The aim of this study was to investigate the relationship between poor mental health and risky sexual behavior (HIV/AIDS) among a population of university students in Uganda. METHODS: In 2005, 980 Ugandan university students completed

Tailored Formation of N-Doped Nanoarchitectures by Diffusion-Controlled on-Surface (Cyclo)-Dehydrogenation of Heteroaromatics

Surface-assisted cyclodehydrogenation and dehydrogenative polymerization of polycyclic (hetero)aromatic hydrocarbons (PAH) are among the most important strategies for bottom-up assembly of new nanostructures from their molecular building blocks. Although diverse compounds have been formed in recent years using this methodology, a limited knowledge on the molecular machinery operating at the nanosc

Laccase catalysed modification of lignin subunits and coupling to p-aminobenzoic acid

Laccase catalysed oxidation of syringyl and guaiacyl subunits of lignin and their modification with an aromatic amine, p-aminobenzoic acid (PABA) were investigated. Laccase from Galerina sp. HC1 isolated earlier by us was used as the main catalyst, and Trametes versicolor laccase was used for comparison. Among the syringyl compounds, syringic acid and syringaldehyde were oxidised to 2,6-dimethoxy-

An 11mW Continuous Time Delta-Sigma Modulator with 20 MHz Bandwidth in 65nm CMOS

This paper presents a multi-bit, continuous time delta-sigma modulator with 20 MHz bandwidth implemented in 65nm CMOS for cellular communication. The modulator features a third order, single loop filter and a 4-bit internal quantizer operating at 640 MHz. The DACs are resistive for lower thermal noise compared to the current-steering DACs and nonreturn-to-zero DAC pulse is used to reduce the clock

Scientific mobility and international research networks: trends and policy tools for promoting research excellence and capacity building

One of the ways in which globalization is manifesting itself in higher education and research is through the increasing importance and emphasis on scientific mobility. This article seeks to provide an overview and analysis of current trends and policy tools for promoting mobility. The article argues that the mobility of scientific labour is an indispensable prerequisite for building capacity and w

Impact of plasma dynamics on equivalence ratio measurements by laser-induced breakdown spectroscopy

The systematic errors introduced by triggering a USB spectrometer for laser-induced breakdown spectroscopy equivalence ratio measurements are studied. We analyze the temporal behavior of laser-induced plasma in a nonreacting methane/air mixture and investigate the influence of the dynamics on equivalence ratio measurements with gated and ungated detection. For use of gated detectors, optimal delay

Heparan sulfate side chains have a critical role in the inhibitory effects of perlecan on vascular smooth muscle cell response to arterial injury

Perlecan is a proteoglycan composed of a 470-kDa core protein linked to three heparan sulfate (HS) glycosaminoglycan chains. The intact proteoglycan inhibits the smooth muscle cell (SMC) response to vascular injury. Hspg2(Delta 3/Delta 3) (M Delta 3/Delta 3) mice produce a mutant perlecan lacking the HS side chains. The objective of this study was to determine differences between these two types o

HIF-1α can act as a tumor suppressor gene in murine Acute Myeloid Leukemia.

Self-renewal of hematopoietic stem cells (HSCs) and leukemia-initiating cells (LICs) has been proposed to be influenced by low oxygen tension (hypoxia). This signaling, related to the cellular localization inside the bone marrow niche and/or influenced by extrinsic factors, promotes the stabilization of hypoxia inducible factors (HIFs). Whether HIF-1α can be used as a therapeutic target in the tre