Abstract Work on the design, synthesis, and biological evaluation of galectin inhibitors is presented. The most significant results relate to the development of galactose-based arginine “tweezers” and taloside-based galectin inhibitors. The galectins are a β-galactoside binding protein family. They are involved in cancer and inflammation, thus comprising interesting pharmaceutical targets. Galact

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Roman glass from indigenous sites is a key source material for studying the impact of Rome on Iron Age Scotland, but it has never been properly studied. This work fills that gap. This study is based on the Roman glass vessels found on non-Roman/native sites north of Hadrian’s Wall, dated mainly to the Roman Iron Age (AD 10-400 AD). These often-overlooked broken sherds of glass are shown to be pa

Popular Abstract in Swedish Syftet med denna avhandling var att undersöka olika aspekter på intersubjektivitet, metakognitiv utveckling och mellanmänsklig förståelse. Mer precist var syftet att undersöka hur några specifika teorier – mentaliseringsteorin, teorin om primär intersubjektivitet, samt interaktionsteorin – beskriver vilken roll intersubjektivitet har att spela i denna utveckling. De förThe aim of the thesis was to examine different aspects of the role of intersubjectivity in metacognitive development and in social understanding. More specifically, it investigates how different theoretical frameworks, such as mentalization theory, the theory of primary intersubjectivity, and interaction theory describe the developmental role of intersubjectivity. The suggestions these theories ma

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We analyze empirically product-price variation across export destinations using detailed firm-product data. Most recent studies using highly disaggregated data emphasize variations in product quality as an explanation as to why firms charge different prices for the same product on different export markets. In this paper, we take an alternative approach and assume that variations in firms' export p

A novel code construction based on spatially coupled low-density parity-check (SC-LDPC) code chains is presented. The proposed code ensembles are described by graphs in which individual SC-LDPC code chains of various lengths serve as edges. We demonstrate that connecting several appropriately chosen SC-LDPC code chains results in improved iterative decoding thresholds compared to those of a single

As the identification process is based on the unique patterns of the users, biometrics technologies are expected to provide highly secure authentication systems. The existing systems using fingerprints or retina patterns are, however, very vulnerable. One’s fingerprints are accessible as soon as the person touches a surface, while a high resolution camera easily captures the retina pattern. Thus,

Popular Abstract in Swedish Patienter som lider av kronisk njursvikt måste avlägsna extracellulärt vatten och slaggprodukter från kroppen för att överleva. Ett alternativ är behandling med peritoneal dialys (PD). Vid en PD behandling fylls och töms bukhålan kontinuerligt med en till tre liter PD vätska fyra gånger om dagen som oftast innehåller glukos som osmotiskt agens. Glukosen skapar ett osmotPatients suffering from renal failure must remove extracellular water and waste products from their body in order to survive. One way of doing this is by treatment with peritoneal dialysis (PD). During PD treatment the abdominal cavity is filled and drained continuously with one to three liters of dialysis solution, often containing glucose, which act as an osmotic agent. Glucose creates a pressur

Popular Abstract in Swedish Fältskiktet gör skillnaden! Dynamiken av näringsämnen och organiskt material i bokskogens övre markskikt Frida Andreasson, Växtekologi och systematik, Lunds universitet Det övre markskiktet i bokskogen är markens mest biologiskt aktiva del. Därför är kunskapen om denna del av marken, dess egenskaper och kemi, angelägen. Särskilt viktig är kunskapen om mineraliseringeThe objective of this thesis was to quantify differences between adjacent patches with and without ground flora of Deschampsia flexuosa L. Trin or Anemone nemorosa L. in two acid European beech (Fagus sylvatica L.) forest floors in south-west of Sweden. The studies included soil properties and chemistry, N mineralisation and bioavailability of dissolved organic carbon (DOC), in soil leachates (SL)

AbstractThe uptake of different nitrogen forms by understory species was studied in field and laboratory. Species of the understory in deciduous forests have previously been thought to take up and assimilate only inorganic nitrogen sources. However, species also have the opportunity to assimilate amino acids, usually in low rates compared with ammonium, according to solution culture studies, but m

The study accounts for recent developments in corporate voluntarism and assesses the evolving corporate social responsibility (CSR) regime. CSR proposes a new norm for how large businesses should approach complexity in a modern economy. The first chapter anchors the CSR discussion in a company law and corporate governance context. Emphasis is placed on managerial duties and the British Review of C