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Detailed assessment of hypothalamic damage in craniopharyngioma patients with obesity

Background/objectives: Hypothalamic obesity (HO) occurs in 50% of patients with the pituitary tumor craniopharyngioma (CP). Attempts have been made to predict the risk of HO based on hypothalamic (HT) damage on magnetic resonance imaging (MRI), but none have included volumetry. We performed qualitative and quantitative volumetric analyses of HT damage. The results were explored in relation to feed

Absolute or relative voice rest after phonosurgery : a blind randomized prospective clinical trial

Objectives: The first aim, was to compare participant compliance with postoperative voice rest advice in two groups. The second aim was to compare vocal function and recovery in the short-term, seven days post-surgery and in the long-term, 3–6 months post-surgery. Design: Preliminary randomized prospective blind clinical trial. Methods: Twenty patients scheduled for surgery for benign vocal fold l

LES of hydrogen enriched methane/air combustion in the SGT-800 burner at real engine conditions

DLE (Dry Low Emission) techniques are widely used today to reduce the harmful NOx emissions associated with high combustion temperatures. In many DLE systems the fuel and air are premixed which effectively keep the flame temperature as low as possible, ideally equal to the turbine inlet temperature. By using premixing stability issues such as flash back and combustion driven dynamics may occur. Op

In Silico Identification and in Vitro Analysis of B and T-Cell Epitopes of the Black Turtle Bean (Phaseolus Vulgaris L.) Lectin

Background/Aims: The incidence of lectin allergic disease is increasing in recent decades, and definitive treatment is still lacking. Identification of B and T-cell epitopes of allergen will be useful in understanding the allergen antibody responses as well as aiding in the development of new diagnostics and therapy regimens for lectin poisoning. In the current study, we mainly addressed these que

Water-silicone oil two-phase flow hydrodynamics in a square glass microchannel

This work visualized water-silicone oil two-phase flow patterns both at the inlet cross-junction and in the main square microchannel with a channel width of 400 µm. Tubing/threading, dripping and jetting were identified at the inlet junction while annular, slug and droplet flows were categorized in the main microchannel at 50 mm downstream of the junction. Flow patterns were represented in terms o

Shifted equilibria of organic acids and bases in the aqueous surface region

Acid-base equilibria of carboxylic acids and alkyl amines in the aqueous surface region were studied using surface-sensitive X-ray photoelectron spectroscopy and molecular dynamics simulations. Solutions of these organic compounds were examined as a function of pH, concentration and chain length to investigate the distribution of acid and base form in the surface region as compared to the aqueous

A machine learning approach to fault detection in district heating substations

The aim of this study is to develop a model capable of predicting the behavior of a district heating substation, including being able to distinguish datasets from well performing substations from datasets containing faults. The model developed in the study is based on machine learning algorithms and the model is trained on data from a Swedish district heating substation. A number of different mode

Selection, drift, and introgression shape MHC polymorphism in lizards

The major histocompatibility complex (MHC) has long served as a model for the evolution of adaptive genetic diversity in wild populations. Pathogen-mediated selection is thought to be a main driver of MHC diversity, but it remains elusive to what degree selection shapes MHC diversity in complex biogeographical scenarios where other evolutionary processes (e.g. genetic drift and introgression) may

Esprit for multidimensional general grids

We present a method for complex frequency estimation in several variables, extending the classical one-dimensional ESPRIT algorithm, and consider how to work with data sampled on nonstandard domains, i.e., going beyond multirectangles.

Systematic Review of Combination Drug Therapy for Non-neurogenic Lower Urinary Tract Symptoms

Context: Several drugs are approved and available for the treatment of lower urinary tract symptoms (LUTS) in men and women. However, the vast majority of available data, upon which the approval and recommendation in guidelines are based, considered only the role of the monotherapies and did not evaluate possible combination therapies. Objective: This systematic review analyzes the efficacy and ad

Experimental assessment of bench-scale ignitability parameters

This work aims to explore possible ways of improving the precision of ignition measurements in the cone calorimeter. Both inherent repeatability of parts of the testing equipment and operator-dependent variations are considered. Inherent repeatability is indicated to be slightly improved if the test samples used are circular rather than square. Operator-dependent variation is discussed in terms of

Plant Traits are Key Determinants in Buffering the Meteorological Sensitivity of Net Carbon Exchanges of Arctic Tundra

The climate sensitivity of carbon (C) cycling in Arctic terrestrial ecosystems is a major unknown in the Earth system. There is a lack of knowledge about the mechanisms that drive the interactions between photosynthesis, respiration, and changes in C stocks across full annual cycles in Arctic tundra. We use a calibrated and validated model (soil-plant-atmosphere; SPA) to estimate net ecosystem exc

Teaching university teachers to become better teachers : the effects of pedagogical training courses at six Swedish universities

Do pedagogical training courses for university teachers have desirable effects on the participants? We set out to answer this question by following a panel of 183 university teachers from Sweden’s six largest universities, who participated in pedagogical training courses. Our study reveals that the participants’ self-reported confidence in their role as teachers increased slightly, and their self-

Heart preservation

In clinical transplantation today, the donor heart is preserved with cold ischemic storage that gives safe preservation for 4 hours. Non-ischemic perfusion preservation is able to preserve the donor heart for 24 hours in pre-clinical studies. The aim of this thesis is to investigate: 1. how potassium, magnesium, and temperature affect the coronary artery contractility; 2. how much oxygen a cardiop

The Coloniality of Taste : A political ecology of middle class food practices in a Bolivian city

Staden Cochabamba kallas för “Bolivias kulinariska huvudstad”. Många kulinariska traditioner och kulturer möts där. Den här avhandlingen handlar om hur den vardagliga matkulturen är en del av reproduktionen av historiska ojämlikheter mellan olika delar av befolkningen, särskild mellan ursprungsbefolkningen och befolkningen som betraktar sig som ”västerländsk”. Avhandlingen utgörs av en inledande dCochabamba city, also referred to as the “gastronomic capital of Bolivia”, is a place where different cultures and tastes meet. Indulging in rich culinary traditions is a part of everyday life, but so are social differentiations reproducing long-standing inequalities between the indigenous and the non-indigenous population. In this thesis, the practices and politics surrounding food are used as a

Urban-Based Agriculture and Poultry Production : The Case of Kisumu and Thika in Kenya

Kenya’s population is rapidly growing and urbanising. Poverty and problems of food insecurity are equally urbanising at an unprecedented rate. Formal employment has not kept pace with the job demand of the growing population. As a result, urban residents seek employment (livelihood) from an array of informal economic activities, including own food production. The growing urban population and urban