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A randomised RSA study of Peri-apatite((TM)) HA coating of a knee prosthesis

Fifty knees scheduled for a total knee prosthesis were randomized in two groups. Both groups had a noncemented fixation of the porous-coated implants but one group received a prosthesis with ceramic coating on the porous surface of the implant. The knees were evaluated with RSA technique regarding micromotion the first two years. There were less micromotion in the coated group. The results indicat

Some indolic compounds as markers of the melanocyte activity

The melanocyte activity was studied by analysis of the urinary excretion of indolic and cysteinyldopa compounds. One eumelanin marker, 5,6-dihydroxy-indole-2-carboxylic acid was identified and quantified in normal urine. However, its low concentration and sensitivity to oxidation made it less suitable for clinical studies. A methylated derivative of this substance, 6-hydroxy-5-methoxyindole-2-carb

Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis

Fibronectin performs essential roles in embryonic development and is prominently expressed during tissue repair. Two forms of fibronectin have been Identified: plasma fibronectin (pFn), which Is expressed by hepatocytes and secreted In soluble form into plasma; and cellular fibronectin (cFn), an insoluble form expressed locally by fibroblasts and other cell types and deposited and assembled into t

Repeatability of sonographic measurements in clubfeet

Purpose: To assess the intra- and interobserver agreement of ultrasound assessment of clubfoot patho-anatomy in early childhood. Material and Methods: Seventeen clubfeet in 12 children were sequentially scanned by 2 examiners and repeat assessments were carried out independently. Three well-defined imaging planes were chosen to evaluate navicular displacement: the medial malleolus-navicular (MM-N)

Health care utilisation in a developing country -the case of Zambia

Popular Abstract in Swedish Syftet med denna avhandling är att bidra till vår förståelse för vårdutnyttjande och dess förklaringsfaktorer i utvecklingsländer, speciellt i sub-sahariska Afrika. Detta görs genom att fokusera på sjukvårdsutgifter och dess förklaringsfaktorer, samt valet att söka vård för att bota åkomman. Datamaterialete som används kommer från en hushållsundersökning från 1998 omfatThe aim of this thesis is to contribute to our understanding of health care utilisation and its determinants in developing countries, especially in sub-Saharan Africa. This is done by explicitly focusing on health care expenditures and its determinants as well as the choice to seek health care to cure the illness. Firstly, the focus is on a household’s expenditures for health care. The aim of this

Early TCR alpha beta expression promotes maturation of T cells expressing Fc epsilon RI gamma containing TCR/CD3 complexes

In a previous study we presented data indicating that the expanded population of CD4(-)CD8(-) (DN) alphabeta T cells in TCRalpha-chain-transgenic mice was partially if not entirely derived from gammadelta T cell lineage cells. The development of both gammadelta T cells and DN alphabeta T cells is poorly understood; therefore, we thought it would be important to identify the immediate precursors of

EEG depression and germinal layer haemorrhage in the newborn

Amplitude integrated EEG (aEEG) recordings from 32 mechanically ventilated infants, gestational age 32 weeks or less, were analysed. All recordings were started within 24 h of birth and continued for at least 50 h. Germinal layer haemorrhage (GLH) was diagnosed by repeated ultrasonography. In six infants neither GLH nor hypocalcaemia were diagnosed; aEEG in these infants rapidly became more active

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Direkt Profil est un analyseur automatique de textes écrits en français comme langue étrangère. Utilisant des techniques du Traitement Automatique des Langues (TAL), son but est de produire une évaluation du stade de développement des apprenants sous la forme d’un profil grammatical. Direkt Profil réalise une analyse des phrases fondée sur des itinéraires d’acquisition, i.e. des phénomènes morphos

Disseminated infection with Encephalitozoon intestinalis in AIDS patients: Report of 2 cases

Microsporidiosis must be regarded as a late opportunistic infection when HIV is advanced. In this article we describe 2 cases of disseminated infection with Encephalitozoon intestinalis. The first case had a local intestinal infection for > 1 y before it disseminated and microsporidia were found intracellularly in sputum. In the second case, spores were initially found in conjunctival cells, sinus

Progenitor cells in the postnatal central nervous system, characterization and genetic manipulation

New neurons are only generated in two places of the postnatal brain; the subventricular zone (SVZ) and hippocampus. The SVZ-derived cells specifically migrate to the olfactory bulb where they give rise to new interneurons. We have genetically manipulated the postnatal SVZ progenitor cells with the aim to direct them to a neuronal fate in the striatum. Our result showed that ectopic expression of t

Pain in older adults living in sheltered accommodation--agreement between assessments by older adults and staff

This study aimed to investigate the presence of pain, pain duration, localization(s), intensity, type and pharmacological treatment among older adults living in sheltered accommodation or receiving rehabilitation, as well as the agreement between pain assessments performed by staff and the older adults. Twenty-nine randomly selected older adults (65+ years) and the staff who looked after them part

Beneficial effects of ACTH on the serum lipoprotein profile and glomerular function in patients with membranous nephropathy

BACKGROUND: Previous studies have shown that short-term treatment with adrenocorticotrophic hormone (ACTH) has a strong and rapid lipid-lowering effect. In this long-term study of nephrotic patients with idiopathic membranous nephropathy, the influence of ACTH on the serum lipoprotein profile and glomerular function as well as the dose-effect relationship was investigated. METHODS: Fourteen patien

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Popular Abstract in Swedish Med föreliggande avhandling vill jag belysa att Chrétien de Troyes Graalsaga, till skilnad från vad de åtskilliga kritiker har påstått, inte bygger på traditionella ridderliga värden, men väl avslöjar en problematisk ideologi. Denna ideologi prövas med hjälp av V. Jouves metod, som beskrivs i hans Poétique des valeurs. Graalsagans värden analyseras ur ett dubbelt perspThis dissertation aims at showing that Chrétien de Troyes' Conte du Graal does not, as often affirmed, uphold traditional chivalrous values, but discloses a problematic ideology, mostly as a result of multiple interactions at the textual level. In order to examine ideology, Le Conte du Graal is analysed in the light of the poetics elaborated by Vincent Jouve in his Poétique des valeurs (2001). Fol

Determination of the pore-size distribution in gels

A method for determination of the accessible volume fraction in gels as function of the molecular weight of the solutes is presented. The pore-size distribution is determined by measuring the rate of diffusion of a mixture of solutes into a gel using gel filtration for separation. The solutes, of various sizes, are detected by refractive index measurements. Two marker molecules (blue dextran and g