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Control theory is one of the key intellectual underpinnings that allows us to analyze the interaction of software with the physical world. However, control theory abstracts software actions as actions that take no time to execute. In reality, software execution takes time – and this execution time can be affected by a number of platform issues, including the speed of the processor, the scheduler u

This study presents an experimental data-set describing movement and behaviours of pre-school children. Data is presented together with detailed information about the evacuation procedure and the data collection methods, in order to enable a comprehensive interpretation of the results and to enhance the understanding of pre-school children evacuation. Data was collected during two semi-announced e

Aims: To compare growth variability of Scots pine (Pinus sylvestris L.) on different soil types, and to assess the potential of peat-soil pines for climatological and hydrological studies.Methods: We used extensive dendrochronological anal- yses to investigate temporal and spatial responses of pines growing on peat soils and mineral soils in three regions of Lithuania.Results: Significant correlatAimsTo compare growth variability of Scots pine (Pinus sylvestris L.) on different soil types, and to assess the potential of peat-soil pines for climatological and hydrological studies.MethodsWe used extensive dendrochronological analyses to investigate temporal and spatial responses of pines growing on peat soils and mineral soils in three regions of Lithuania.ResultsSignificant correlations wer

The importance of long-term historical information derived from paleoecological studies has long been recognized as a fundamental aspect of effective conservation. However, there remains some uncertainty regarding the extent to which paleoecology can inform on specific issues of high conservation priority, at the scale for which conservation policy decisions often take place. Here we review to whaThe importance of long-term historical information derived from paleoecological studies has long been recognized as a fundamental aspect of effective conservation. However, there remains some uncertainty regarding the extent to which paleoecology can inform on specific issues of high conservation priority, at the scale for which conservation policy decisions often take place. Here we review to wha

För 50 år sedan började man operera utslitna höftleder och använda konstgjordaledytor som ersättning. Antalet operationer har långsamt ökat och operationen är nu en av de vanligaste i Sverige. En ny höftled leder oftast till total smärtfrihetoch ökad rörelseförmåga under lång tid men ibland kan de insatta delarna lossna. Omoperationer på grund av proteslossning ökar i antal och för närvarande utgö

Socio-economic inequalities are remarkable in contemporary developed countries and continue to grow. The sources of these phenomena are not understood, and there is no agreement as to when in an individual’s life they originate, from early childhood to adulthood. The literature showing that health in infancy may be an important factor in later-life health and income trajectories is expanding, but

A method is described for measuring middle-latency auditory evoked potentials (MLAEP) in consciously awake, non-sedated pigs during the induction of thiopentone anaesthesia (0.6 ml/kg, 2.5% thiopentone solution). It was done by using autoregressive modelling with an exogenous input (ARX). The ability to perceive pain during the induction was compared with (1) the changes in latencies and amplitude

Monoamine neurotransmitters play an important role in the modulation of sensory, motor and autonomic functions in the spinal cord. Although traditionally it is believed that in mammalian spinal cord, monoamine neurotransmitters mainly originate from the brain, accumulating evidence indicates that especially when the spinal cord is injured, they can also be produced in the spinal cord. In this revi

A peptidomimetic called A20 (Cystapep 1) structurally based upon the N-terminal fragment of human cystatin C is known to have strong antibacterial properties. A20 is characterized by high activity against several bacterial strains often isolated from infected wounds, including methicillin-resistant S. aureus (MRSA). In this work we wanted to explore the therapeutic potential of A20 in the treatmen

Background: Treatment with methotrexate (MTX) in patients with rheumatoid arthritis (RA) leads to decreased total immunoglobulin (Ig) levels and impairs vaccine-specific IgG antibody levels following pneumococcal vaccination. The mechanisms by which MTX exerts these effects in RA are unknown. We aimed to evaluate whether MTX reduces vaccine-specific serum Ig levels and their functionality in RA pa

Mechanical damage at the time of joint injury and the ensuing inflammatory response associated with elevated levels of pro-inflammatory cytokines in the synovial fluid, are reported to contribute to the progression to osteoarthritis after injury. In this exploratory study, we used a targeted proteomics approach to follow the progression of matrix degradation in response to mechanical damage and cy