Objective: To perform genetic linkage analysis in a family affected with ALS and frontotemporal dementia (FTD). Methods: The authors performed a genome-wide linkage analysis of a four-generation, 50-member Scandinavian family in which five individuals were diagnosed with ALS and nine with FTD. Linkage calculations assuming autosomal dominant inheritance of a single neurodegenerative disease manife

The present study examined the rheological blood velocity profile in the conduit femoral artery during rhythmic muscle contractions at different muscle forces. Eight healthy volunteers performed one-legged, dynamic knee-extensor exercise at work rates of 5, 10, 20, 30, and 40 W at 60 contractions per minute. The time and space-averaged, amplitude-weighted mean ( V-mean) and maximum (V-max) blood f

Using a numerical simulation of compressible convection with radiativetransfer mimicking the solar photosphere, we compare the velocity fieldderived from granule motions to the actual velocity field of the plasma.We thus test the idea that granules may be used to trace large-scalevelocity fields at the sun's surface. Our results show that this isindeed the case provided the scale separation is suf

The inverse scattering problem on the half-axis for long range potentials is studied. It is shown that the solution of the inverse problem contains arbitrary real parameters iven if no bound states are present. Connections with the inverse problem on the whole axis are discussed.

Uncracked reinforced concrete slabs have been field exposed at the Träslövsläge marine field station at the Swedish west coast since April 1992. This report is a compilation of the total chloride profiles and calculated chloride transport rates in 13 concrete mixes exposed for 1, 2 and 5 years.

PURPOSE: To describe new disease-causing RP2 and RPGR-ORF15 mutations and their corresponding clinical phenotypes in Swedish families with X-linked retinitis pigmentosa (XLRP) and to establish genotype-phenotype correlations by studying the clinical spectrum of disease in families with a known molecular defect. METHODS: Seventeen unrelated families with RP and an apparent X-linked pattern of disea

Recension av Sverker Oredsson, Svensk rädsla. Offentlig fruktan i Sverige under 1900-talets första hälft

Objective: To evaluate existing models for the origin of meta- and synchronous urothelial carcinomas in light of the accumulated genetic data. Methods: Published studies on the clonal origin and genetic relationships of syn- and metachronous tumors, genetic aberrations in normal and premalignant urothelial lesions, as well as histologic and genetic mapping studies of cystectomized bladder samples

The deposition of polystyrene latex particles (0.23 mum in radius) onto a glass surface, covered with indium-tin oxide, has been studied using a wall-jet cell. The particle deposition could be followed in a single experiment at several positions, exposed to a wide range of wall shear rates. A deposition model including a shielding function was applied in order to describe the process. Three shield

On the representation of immigrants in recent Swedish cinema.

This paper reports on a pilot demonstration to implement an alcohol consumption reduction project in the community of Kirseberg, located in the city of Malmo, Sweden. The objective is to present data on time trends in alcohol use habits and alcohol-use-related problems in the Kirseberg population and to discuss potential effects of the alcohol prevention activities. It was possible to implement an

RATIONALE AND OBJECTIVES: The authors determined the usefulness of performing videoradiography and pharyngeal solid-state manometry during barium swallow in dysphagic patients with pharyngeal retention. METHODS: Results were retrospectively analyzed of simultaneous videoradiography and manometry examinations in 14 patients with retention of barium in the pharynx. Twelve age-matched patients withou

We present the excited state dynamics of the low band gap alternating polyfluorene copolymer, DiO-PFDTBT. The copolymer structure is an alternating sequence of donor and acceptor units consisting of 9,9-dioctyl-9H-fluorene and 4,7-di-thiophen-2-yl-benzo[1,2,5]thiadiazolyl units. Calculations have predicted that the first excited state has charge transfer character, while the second strongly allowe

This paper describes the design, development and characteristics of a tyrosinase (polyphenol oxidase) modified amperometric screen-printed biosensor array, with the enzyme cross-linked in a redox-hydrogel namely the PVI13-dmeOs polymer. Two types of Au-screen-printed four-channel electrode arrays, differing in design and insulating layer, were compared and investigated. Au-, graphite-coated-Au- an