p16(INK4a), p15(INK4b), p18(INK4c) and p19(INK4d) comprise a family of cyclin-dependent kinase inhibitors and tumor suppressors. We report that the INK4 proteins share the ability to arrest cells in G1, and interact with CDK4 or CDK6 with similar avidity. In contrast, only p18 and particularly p19 are phosphorylated in vivo, and each of the human INK4 proteins shows unique expression patterns depe

Kulturartikel om animationsfilm och tecknandets förändring med datoranimationens tekniska genombrott.

The primary aim of this study is to view the meaning, the function and the consequences of appealed community plans. A overview of the Swedish regulations has been made in addition to an empirical study of 63 appealed community plans in two municipalities in the south of Sweden, during the years 1996-2000. The study shows that approximately 25% of all the plans made have been the object for appeal

Chaos in time: On the consequences of chaos-theory in the study of the past. The importance of minor events is stressed and the part and the whole are related in a new way.

BACKGROUND: Huntington’s Disease (HD) is a hereditary, progressive neurodegenerative disorder characterised by both neurological and systemic symptoms. In HD, immune changes can be observed before the onset of overt clinical features raising the possibility that immune markers in plasma could be used to track disease progression. It has previously been demonstrated that a widespread, progressive i

This article studies continued childbearing and union stability among "power couples," or dual-career couples. The determinants of these events are analysed multivariately using longitudinal data on couples from population registers in Sweden, 1991–2005. Power couples are identified using their levels and fields of education, and their sectors of employment. Income and other variables are controll

Scand J Caring Sci; 2011 Wellbeing among people with dementia and their next of kin over a period of 3 years Little is known about the dyadic experience over time of people with dementia and their next of kin. The aim of this study was to investigate the state of mind of people with dementia, their next of kin's experience of burden and satisfaction, and factors associated with these experiences o

Increasing fuel prices and environmental concern drives the research and development for the internal combustion engine. Homogeneous Charge Compression Ignition (HCCI) is a promising combustion concept with high fuel efficiency and low emissions. The auto-ignition in HCCI combustion has no flame propagation and therefore the combustible mixture is consumed rapidly, even at low temperature. This re

Lewis' concept of admissibility was introduced as an integral part of his famous Principal Principle; the principle that initial rational/reasonable belief should conform to objective chance unless there is evidence to the contrary. At that time Lewis offered only the rough and ready characterisation that evidence not to the contrary of such dependence is admissible. This, together with some suffi

Review of Göran Tegnér (ed), “Gråborg på Öland. Om en borg, ett kapell och en by” (Stockholm 2008).