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Viruses are the most abundant and genetically diverse entities on Earth, yet the functions and evolution of most viral proteins remain poorly understood. Their rapid evolution often obscures evolutionary relationships, limiting the ability to assign functions using sequence-based methods. Although the conservation of protein fold can reveal deep homologies, viral proteins remain underrepresented i

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BACKGROUND AND PURPOSE: Treatment of cancer with immune checkpoint inhibitors (ICIs) entails a risk of immune-related adverse events (irAEs). Data on the treatment of immune-related enterocolitis (irEC) in patients with inadequate symptom control after treatment with standard therapy including corticosteroids, infliximab, and vedolizumab are scarce. Based on limited data, recommendations include t

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Background: The continuum of care (CoC) for maternal health, which includes ≥4 antenatal care (ANC) visits, delivery assisted by skilled birth attendants, and a postnatal care (PNC) visit within 48 hours of delivery, is a crucial health care package associated with survival and improved health outcomes for children and mothers. In addition, the CoC serves as a platform for delivering messages and

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In recent years, international scientific collaboration has become increasingly entangled with geopolitical tensions, especially between China and Western countries. While institutional and policy-level analyses have offered important insights, relatively little is known about how these global dynamics are experienced and navigated by individual researchers within China. Drawing on the analytical

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Feather mites play an important role in bird communities, covering a wide spectrum of associations with their hosts, ranging from parasitic to mutualistic relations. As a result of long co-evolution with their warm-blooded hosts, this diverse group of arthropods can be found in a wide range of environments where their hosts occur, including the high Arctic. The feather mite fauna of Greenland is p

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Den här översikten sammanställer kunskap om hur skolors vardag har kommit att påverkas av införandet av en digital enhet, exempelvis bärbar dator, per elev (1:1). Frågan om huruvida införanden av en dator per elev höjer kunskapsresultat och måluppfyllelse har ställts av många och översikten tar upp hur det har utvärderats i Sverige och inte funnit sådana effekter. Mot den bakgrunden är det relevan

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Since the rise of radical geography in the early 1970s, political economy has been crucial in examining the spatial dynamics of capital in economic geography. Marxist and non-Marxist (particularly institutionalist) economic geographers use political economy to challenge non-political economy approaches that ignore the relationship between microeconomic processes and their spatial manifestations an

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This paper analyses structural economic forces contributing to the current undersupply of affordable housing in Sweden’s third-largest city, Malmö. It operationalizes Anwar Shaikh’s theory of relative prices to analyzethe political economy of housing shortage. The paper argues that existing policy recommendations at the municipal level are primarily informed by a microeconomic approach to price fo

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Neuroblastoma (NB) is an aggressive pediatric solid tumor which often develops chemoresistance. Ferroptosis is a potential vulnerability in NB, but its interplay with chemoresistance and standard-of-care chemotherapy is not known. Here, we report that key antioxidant pathways are enriched in refractory NB, and that ferroptosis can be induced in NB through various mechanisms of action (MOA) in vitr

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This paper analyses structural economic forces contributing to the current undersupply of affordable housing in Sweden’s third-largest city, Malmö. It operationalizes Anwar Shaikh’s theory of relative prices to analyze the political economy of housing shortage. The paper argues that existing policy recommendations at the municipal level are primarily informed by a microeconomic approach to price f

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A search is presented for direct pair production of the stop, the supersymmetric partner of the top quark, in a decay through an Formula Presented-parity violating coupling to a charged lepton and a Formula Presented-quark. The dataset corresponds to an integrated luminosity of Formula Presented of proton-proton collisions at a center-of-mass energy of Formula Presented collected between 2015 and