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Plasminogen activator inhibitor-1 (PAI-1) functions as an important regulator of fibrinolysis by inhibiting both tissue-type and urokinase-type plasminogen activator. PAI-1 is produced by smooth muscle cells (SMCs) in atherosclerotic arteries, but the mechanisms responsible for induction of PAI-1 in SMCs are less well understood. In cultured human aortic SMCs, PAI-1 mRNA expression and protein sec
Interest in learning in mature adulthood has become increasingly important as attention has been focused on what is seen to be an impending crisis in the near future, i.e., shortage of labour due to the ever-growing number of elderly and decreasing nativity rates. In some circles "alarmist demographics" have overshadowed an arguably more important concern, that of providing for aging individuals'
In this lecture, we will discuss the emergence of the semiotic function, both ontogenetically and phylogenetically, and we will consider the part played by the picture sign in this development. In order to demonstrate that pictures are indeed signs, we will explore the basic elements of the sign presupposed but never put into focus neither by Saussure nor by Peirce. Indeed, explorations in the psy
Newspapers and net papers are examples of complex multimodal documents consisting of texts, pictures and graphics. Although we encounter such documents in our everyday life, there is still little empirical evidence about how these formats are processed by readers. In our paper, we discuss myths about readers’ interaction with complex visual documents from the perspective of contrary empirical evid
Popular Abstract in Swedish Idag har kravet på kortare ledtider i bilindustrin dramatiskt ökat behovet av effektivare utvecklingsmetoder vid varje steg i processutvecklingskedjan. För att minska de långa ledtiderna för framtagning av ett formningsverktyg har man introducerat Finita Element (FE) simulering av formningsprocessen. Även om FE-simulering används inom bilindustrin idag finns fortfarandeToday, shortened lead-times in the automotive industry have dramatically increased the need for more efficient development methods at every stage of the process development chain. In order to decrease the long lead-time for producing a forming tool, sheet-metal-forming simulation was introduced. Even though sheet-metal-forming simulation is widely used in the automotive industry today, there are s
The European Spallation Source (ESS) is a planned neutron source to be built in Lund, Sweden, which is planned to produce the first neutrons in 2019. It will have an average beam power at the target of 5 MW, an average current along the linac of 50 mA, and a pulse repetition rate and length of 20 Hz and 2.86 ms, respectively. The linac will have around 200 LLRF stations employed to control a varie
Abstract This paper addresses the importance of networks for entrepreneurs in bankruptcy, based on interviews with entrepreneurs who have experienced at least one bankruptcy. Analysis of the interviews reveals two discursive themes: entrepreneurship and bankruptcy. Entrepreneurship is expressed in terms of initiative and of contacts in business contexts; bankruptcy concerns economic marginalizatio
This thesis evaluates the feasibility of designing a coprocessor to accelerate multimedia functions in the OpenMAX standard. OpenMAX is a new standard from the Khronos group, a member funded industry consortium, to integrate the most popular multimedia functions like MP3, MPEG-4 and H.264 under one roof. It provides royalty-free API that helps in developing and/or accelerating the specified standa
