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Popular Abstract in English The sesquiterpene lactones is an important group of natural products, and they are present in many medicinal plants. Their most important biological activities are anti-inflammatory and anti-cancer activity, although for many decades their potential use as drugs was dismissed. The main reason for this was their alkylating capacity, reacting with thiol functions in proteDamsin (1) is a natural sesquiterpene lactone (SL) isolated from Ambrosia arborescens Mill., a plant used in the Andes as antiinflammatory medicine. This natural product is an inhibitor of NF- κB, a protein complex that controls the transcription of many genes in mammalian cells, and has a potential for standing model for the development of new anti-cancer lead structures. In order to improve the

Whilst Building Information Modelling (BIM) promises significant improvements in construction quality and efficiency, current contractual models do not encourage its use; indeed actively inhibit the collaboration at its core. To help bring BIM into the mainstream, it is claimed we need to re-craft existing contractual relationships to facilitate collaborative decision making and to equitably alloc

The Global Energy Assessment (GEA) brings together over 300 international researchers to provide an independent, scientifically based, integrated and policy-relevant analysis of current and emerging energy issues and options. It has been peer-reviewed anonymously by an additional 200 international experts. The GEA assesses the major global challenges for sustainable development and their linkages

Popular Abstract in Swedish Avhandlingen ”Vänskap och organisering. En studie av Fountain House-rörelsen” tar sin utgångspunkt i frågan om vad som händer när mentalsjukhusen läggs ner. Bakgrunden är den process som kallas avinstitutionaliseringen, och tidens betoning på integrering, normalisering och självbestämmande. Omstruktureringen av mentalvården har inte varit problemfri i något land. Många The Fountain House Movement – or the Clubhouse Movement - is an organization for community support, meeting the needs of adults suffering from mental illness. It was founded by a self-help group among discharged patients in New York in the 1940s. Today there are more than 300 clubhouses around the world. The aim of this dissertation is to characterize, interpret and understand the Clubhouse Moveme

Popular Abstract in Swedish Populärvetenskaplig sammanfattning på svenska Datortolkning av myokardscintigrafibilder Kärlkramp och hjärtinfarkt sammanfattas ibland under benämningen ischemisk hjärtsjukdom, en vanligt förekommande sjukdom i många industriländer. Sjukdomen beror främst på förträngningar i hjärtats kranskärl, dvs. de kärl som förser hjärtmuskulaturen med blod. Sjukdomen går att behaIn the studies of this thesis, a method for automated classification of myocardial perfusion images was successfully developed and evaluated. The results show that the method, based on artificial neural networks, was equally good, or even better than human experts. It was also found that physicians interpreting myocardial perfusion images benefit from the advice of the artificial neural networks.

The Great Trajanic Frieze is a Monument firmly entranched in the tradition of Graeco-Roman art.The study of the different components of its imagery, such as composition, iconography and antiquarian details, reveals how it transmits and transforms this tradition. The imagery reveals itself as conscentiously structured to present and repeat a limited set of concepts to the viewer. The book also pres

The aim of this thesis has been to investigate self-diffusion behavior of host-guest complex, microemulsion and polymer solution. Pulsed Field Gradient NMR (PFG-NMR) was shown to provide detailed molecular information in all system studied. The general strategy was to measyre the diffusivities of the species and from there get molecular insight into the aggregation and dynamics of the system.

Studies of the long-lived anthropogenic radionuclides 99Tc, 237Np, 239Pu and 240Pu were performed in marine and terrestrial areas contaminated by different accidental and controlled releases of radioactive materials. The three main sources discussed in this thesis are nuclear weapons tests, nuclear reprocessing plants and the Chernobyl accident. Results are mainly based on measurements of environm