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We are reporting on a novel approach for structured immobilisation of enzymes on gold surfaces modified with monolayers of functionalised alkylthiols. The formation of enzyme spots is achieved by shooting very small volumes of an appropriate enzyme solution (down to 100 pl) onto a thiol-monolayer modified gold surface using a micro-dispenser. Formation of enzyme patterns is obtained by moving the

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A limitation on the extinction cross section, valid for all scatterers satisfying some basic physical assumptions, is investigated. The physical limitation is obtained from the holomorphic properties of the forward scattering dyadic. The analysis focuses on the consequences for materials with negative permittivity and permeability, i.e. metamaterials. From a broadband point of view, the limitation

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Kulturartikel om framgången både nationellt och internationellt för den Sydkoreanska filmen i början av 2000-talet.

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Kulturartikel om serieromanförfattaren Alan Moore med anledning av filmverrsionen av hans roman Watchmen.

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Abstract Background. The plasma level of cystatin C is a better marker than plasma creatinine for successful aging. It has been assumed that the advantage of cystatin C is not only due to it being a better marker for glomerular filtration rate (GFR) than creatinine, but also because an inflammatory state of a patient induces a raised cystatin C level. However, the observations of an association be

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Concrete structures in hydro power plants exposed to harsh environment, such as non-frozen freshwater and long cold winters with freezing temperatures, are always in the danger-zone for suffering from concrete damages. Some existing concrete structures already suffer from different damages caused by high water content. The conditions regarding concrete quality, air entrainment, temperature and tim

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BackgroundA suspected occult hip fracture after normal radiography is not uncommon in an elderly person after a fall. Despite a lack of robust validation in the literature, computed tomography (CT) is often used as secondary imaging.PurposeTo assess the frequency and clinical utility of non-cortical skeletal and soft tissue lesions as ancillary fracture signs in CT diagnosis of occult hip fracture

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Thrainsdottir S, Malik RA, Rosén I, Jakobsson F, Bakhtadze E, Petersson J, Sundkvist G, Dahlin LB. Sural nerve biopsy may predict future nerve dysfunction. Acta Neurol Scand: DOI: 10.1111/j.1600-0404.2008.01118.x. (c) 2008 The Authors Journal compilation (c) 2008 Blackwell Munksgaard.Objective - Sural nerve pathology in peripheral neuropathy shows correlation with clinical findings and neurophysio

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Prion protein (PrP) is an endogenous protein involved in the pathogenesis of bovine spongiform encephalopathy and Creutzfeldt-Jakob disease. Murine PrP has been reported to bind C1q and activate the classical pathway of complement in a copper-dependent manner. Here we show that various conformational isoforms (native, amyloid fibrils, and beta-oligomers) of recombinant human PrP (90-231 and 121-23

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T cells have been attributed an important role in modulating repair responses following vascular injury. The aim of this study was to investigate the role of different T cell subsets in this context.

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Growth from straight cracks is studied, both for loading in pure mode I or II and for mixed mode loading. Small scale yielding and a plane condition are assumed. Growth is assumed to take place in either mode I or mode II. Loss of directional stability sometimes occurs even from cracks that seem destined for continued growth straight forward. A striking example is the case of collinear cracks unde

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Abstract in UndeterminedUsing an exact circuit analogy for the scattering ofvector spherical waves, it is shown how the problem of determiningthe optimal scattering bounds for a homogeneous spherein its high-contrast limit is identical to the closely related, andyet very different problem of finding the broadband tuning limitsof the spherical waves. Using integral relations similar to Fano’sbroadb

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BACKGROUND: The rare p phenotype is found at a higher frequency in Amish people than in other populations. Different mutations in the 4-alpha-galactosyltransferase gene (A4GALT), responsible for synthesis of P(k) (Gb(3)) antigen, have been found to cause the P(k)-deficient p phenotype. The aim of this study was to explore the molecular background of the p phenotype in people of Amish origin. STUDY

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PURPOSE: To identify changes in gene expression in the airways among welders, with and without lower airway symptoms, working in black steel. METHODS: Included were 25 male, non-smoking welders. Each welder was sampled twice; before exposure (after vacation), and after 1 month of exposure. From the welders (14 symptomatic, of whom 7 had asthma-like symptoms), RNA from induced sputum was obtained f

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With a method relying on measurements of water vapour flow from a specimen and on measurements of distribution of relative humidity in the specimen at steady state conditions, it is possible to calculate the moisture permeability. Its dependence on relative humidity is presented.