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Related in death? A curious case of a foetus hidden in bishop Peder Winstrup's coffin in Lund, Sweden

When the famous bishop of Lund, Peder Winstrup, died in 1679 he was laid to rest in a family crypt in Lund Cathedral alongside his wife. Following a restoration of the Cathedral in the late 19th century, Peder Winstrup's coffin was moved to the crypt, as the family grave was dismantled. In 2012, a decision was made to move his remains to a different location presenting scientists with an opportuni

Relaxation of electronic excitations in K2GeF6 studied by means of time-resolved luminescence spectroscopy under VUV and pulsed electron beam excitation

Highly crystalline K2GeF6 micropowders were prepared by co-precipitation in the hydrofluoric acid-water-alcohol solution and studied by means of the cathodoluminescence and time-resolved luminescence spectroscopy under synchrotron radiation excitation at 7 K. The nature of various intrinsic emissions was revealed. The luminescence band at 510 nm detected under excitation by photons with the energy

Risk of Rehospitalization and Death in Patients Hospitalized Due to Asthma

Background: Asthma is a heterogeneous inflammatory airway disease that continues to cause considerable morbidity across the world, with poor asthma control leading to hospitalizations. Objective: The present study investigated the risk of rehospitalization, mortality, and the management of patients with asthma who had been hospitalized because of an asthma exacerbation. Methods: National Swedish h

Altered winter conditions impair plant development and yield in oilseed rape

The demand for agricultural products is expected to increase as a result of population growth, changed diets and demands for bioenergy. At the same time, agricultural yields in many regions are expected to be negatively impacted by climate change. Here we show, how altered winter conditions in combination with an extreme weather event impact reproductive development and yield of oilseed rape (Bras

Change patterns of sleep problems predict mental health problems among adolescents : a 10-year cohort study of Chinese Wenchuan earthquake

Background: The predictive effects of change patterns of sleep problems on mental health after a long-term disaster remain poorly known. We examined the change patterns of sleep problems after the Wenchuan earthquake, and tested whether specific sleep-related change patterns could predict mental health problems (posttraumatic stress disorder [PTSD], anxiety, and depression) in the 10 years after W

Evaluating the performance of the OSCORE security protocol in constrained IoT environments

The Constrained Application Protocol (CoAP) is a standard communication protocol for resource-constrained devices in the Internet of Things (IoT). Many IoT deployments require proxies to support asynchronous communication between edge devices and the back-end. This allows (non-trusted) proxies to access sensitive parts of CoAP messages. Object Security for Constrained RESTful Environments (OSCORE)

The screening and evaluation of potential clinically significant HIV drug combinations against the SARS-CoV-2 virus

Spike glycoprotein is essential for the reproduction of the SARS-CoV-2 virus, and its inhibition using already approved antiviral drugs may open new avenues for treatment of patients with the COVID-19 disease. Because of that we analyzed the inhibition of SARS-CoV-2 spike glycoprotein with FDA-approved antiviral drugs and their double and triple combinations. We used the VINI in silico model of ca

A distortional hardening model for finite plasticity

Plastic anisotropy may strongly affect the stress and strain response in metals subjected to multiaxial cyclic loading. This anisotropy evolves due to various microstructural features. We first use simple models to study how such features result in evolving plastic anisotropy. A subsequent analysis of existing distortional hardening models highlights the difference between stress- and strain-drive

Temporal increase in D614G mutation of SARS-CoV-2 in the Middle East and North Africa

Background: Phylogeny construction can help to reveal evolutionary relatedness among molecular sequences. The spike (S) gene of SARS-CoV-2 is the subject of an immune selective pressure which increases the variability in such region. This study aimed to identify mutations in the S gene among SARS-CoV-2 sequences collected in the Middle East and North Africa (MENA), focusing on the D614G mutation,

Early Cambrian brachiopod-dominated shell concentrations from North-East Greenland : Environmental and taphonomic implications

The occurrence of a series of thin but persistent early Cambrian (Cambrian Age 4) brachiopod shell concentrations extending along a transect of some 150 km in NE Greenland, indicates the ability of the group to form widespread, skeletal pavements very early in the history of the phylum, its gregarious behaviour and ability to harness available nutrients. These extensive shell pavements within the

Pilot RCT of the Attempted Suicide Short Intervention Program (ASSIP) adapted for rapid delivery during hospitalization to adult suicide attempt patients with substance use problems

Objective: The Attempted Suicide Short Intervention Program (ASSIP) was adapted for hospital delivery and to address substance use problems as well as evaluated for feasibility, acceptability, and therapist fidelity in a series of preparatory steps (n = 28) and in a pilot randomized controlled trial, RCT (n = 34). Method: In the RCT, patients with suicide attempts and substance use problem(s) with

Systematic detection of functional proteoform groups from bottom-up proteomic datasets

To a large extent functional diversity in cells is achieved by the expansion of molecular complexity beyond that of the coding genome. Various processes create multiple distinct but related proteins per coding gene – so-called proteoforms – that expand the functional capacity of a cell. Evaluating proteoforms from classical bottom-up proteomics datasets, where peptides instead of intact proteoform

Extensive introgression and mosaic genomes of Mediterranean endemic lizards

The Mediterranean basin is a hotspot of biodiversity, fuelled by climatic oscillation and geological change over the past 20 million years. Wall lizards of the genus Podarcis are among the most abundant, diverse, and conspicuous Mediterranean fauna. Here, we unravel the remarkably entangled evolutionary history of wall lizards by sequencing genomes of 34 major lineages covering 26 species. We demo

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Plastic extension of Breviario de espejismos by Elena Mendoza. Glued paper, two speakers, amplifier, video, tablet, LED light, photographic montage, four metal supports, fishing line, metal strings, two wooden boxes, two mixed metal-wooden supports.

Mixed halide perovskites for spectrally stable and high-efficiency blue light-emitting diodes

Bright and efficient blue emission is key to further development of metal halide perovskite light-emitting diodes. Although modifying bromide/chloride composition is straightforward to achieve blue emission, practical implementation of this strategy has been challenging due to poor colour stability and severe photoluminescence quenching. Both detrimental effects become increasingly prominent in pe

Intranasal administration of α-synuclein preformed fibrils triggers microglial iron deposition in the substantia nigra of Macaca fascicularis

Iron deposition is present in main lesion areas in the brains of patients with Parkinson’s disease (PD) and an abnormal iron content may be associated with dopaminergic neuronal cytotoxicity and degeneration in the substantia nigra of the midbrain. However, the cause of iron deposition and its role in the pathological process of PD are unclear. In the present study, we investigated the effects of