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Effect of screening for type 1 diabetes on early metabolic control : the DiPiS study

Aims/hypothesis: It has been shown that children previously enrolled in follow-up studies have better glycaemic control during the early period after diabetes diagnosis. The aim of this study was to analyse glycaemic control over a longer period, past the period of partial remission, after diagnosis in children followed before diagnosis in the Swedish Diabetes Prediction in Skåne (DiPiS) study com

Charting the human lung with inhaled nanoparticles : Development of AiDA - a new diagnostic technique for respiratory disease

Changes to the smallest structures of the distal lung are often the first sign of severe respiratory disease, but to date methods to detect and quantify these changes are limited. Chronic obstructive pulmonary disease (COPD) is currently estimated to be the third most common cause of death worldwide, but is to a large extent under-diagnosed, especially at early stages. This thesis explores a new m

About Not Understanding the System : Ignorance as an Obstacle to a Meaningful Life in Sweden

This presentation builds on several ethnographic fieldworks (2011-2015) in southern Sweden on people who have Palestinian background as well as my on-going informal involvement with Palestinian networks. The field material includes about 35 qualitative interviews, numerous informal discussions and participant observations of political events (mostly demonstrations and lectures) and people’s daily This presentation builds on several ethnographic fieldworks (2011-2015) in southern Sweden on people who have Palestinian background as well as my on-going informal involvement with Palestinian networks. The field material includes about 35 qualitative interviews, numerous informal discussions and participant observations of political events (mostly demonstrations and lectures) and people’s daily

Modeling of structural cables

For many applications, including future giant telescopes, there is increased interest in structural cables. Usually integrated models, i.e. combined models of structures, optics and control systems are used for modeling of telescopes. Performance of structural cables is non-linear, so often a linearization is needed to include cable models in integrated models of telescopes. We present two differe

A taxonomy of deviant encodings

The main objective of this paper is to design a common background for various philosophical discussions about adequate conceptual analysis of “computation”.

Infection events in the fungus-nematode system

Infection of vermiform nematodes by nematophagous fungi generally follows the same route whether the nematode is captured in adhesive traps of predatory fungi or mediated by conidia of endoparasites. A successful infection always results in complete digestion of the nematode corpus. The total time for the infection process varies between fungal species and also between species of nematodes being p

Target-specific forebrain projections and appropriate synaptic inputs of hESC-derived dopamine neurons grafted to the midbrain of parkinsonian rats

Dopamine (DA) neurons derived from human embryonic stem cells (hESCs) are a promising unlimited source of cells for cell replacement therapy in Parkinson's disease (PD). A number of studies have demonstrated functionality of DA neurons originating from hESCs when grafted to the striatum of rodent and non-human primate models of PD. However, several questions remain in regard to their axonal outgro

Computer simulation analysis of source-detector position for percutaneously measured O2-gas signal in a three-dimensional preterm infant lung

Further improvements in the clinical care of our most vulnerable patients-preterm infants-are needed. Novel diagnostic and surveillance tools facilitate such advances. The GASMAS technique has shown potential to become a tool to, noninvasively, monitor gas in the lungs of preterm infants, by placing a laser source and a detector on the chest wall skin. It is believed that this technology will beco

Test-retest reliability of the life satisfaction questionnaire (LISAT-11) and association between items in individuals with chronic stroke

Objective: To evaluate the test–retest reliability of the Life Satisfaction Questionnaire (LiSat-11) and the association between items in individuals with chronic stroke. Design: Test–retest design. Subjects: Forty-five individuals (mean age 65 years) with mild to moderate disability at least 6 months post-stroke. Methods: LiSat-11, which includes 1 global item”Life as a whole” and 10 domain-speci

Effects of Treatment with Adalimumab on Blood Lipid Levels and Atherosclerosis in Patients with Rheumatoid Arthritis

Background: Treatment with tumor necrosis factor inhibitors for rheumatoid arthritis has been associated with a decreased risk of cardiovascular disease in observational studies. There are conflicting data on the influence of tumor necrosis factor inhibitors on lipid levels. Objectives: To evaluate the effect of treatment with adalimumab on blood lipid levels, lipoproteins, and atherosclerosis of

On the zero-stability of multistep methods on smooth nonuniform grids

In order to be convergent, linear multistep methods must be zero stable. While constant step size theory was established in the 1950’s, zero stability on nonuniform grids is less well understood. Here we investigate zero stability on compact intervals and smooth nonuniform grids. In practical computations, step size control can be implemented using smooth (small) step size changes. The resulting g

Anomalous Schottky Signals from a Laser-Cooled Ion Beam

Longitudinal Schottky signals froma laser-cooled, spatially dense, ionbeam have been studied inthe ASTRID storage ring. Thefluctuation signals are distortedby the effects of space charge, asis observed in electron cooling experiments.However,the spectra also exhibit previously unobservedcoherent components. The ions' velocity distribution, measured by alaser fluorescence technique, suggests that t

Brugada syndrome-associated genetic loci are associated with J-point elevation and an increased risk of cardiac arrest

Introduction: A previous genome-wide association study found three genetic loci, rs9388451, rs10428132, and rs11708996, to increase the risk of Brugada Syndrome (BrS). Since the effect of these loci in the general population is unknown, we aimed to investigate the effect on electrocardiogram (ECG) parameters and outcomes in the general population. Materials and Methods: A cohort of 6,161 individua

Sustainability Impact Assessment of Increased Plastic Recycling and Future Pathways of Plastic Waste Management in Sweden

Plastic is a versatile material that has contributed to numerous product innovations and convenience in everyday life. However, plastic production is growing at an alarming rate, and so has the generation of plastic waste. Unsound waste management results in plastic leakage to the environment with multiple adverse effects to ecosystems. Incineration of plastic waste produces excessive greenhouse g

The use of public procurement to incentivize longer lifetime and remanufacturing of computers

Improving the product lifetime of consumer electronics can provide significant environmental benefits. However, there is a tendency among both professional users and consumers to change products, like computers and mobile phones regularly, and as a result their lifetimes become increasingly shorter. With the rise of the Circular Economy, new policies to promote longer product lifetimes have emerge

Five-week yin yoga-based interventions decreased plasma adrenomedullin and increased psychological health in stressed adults : A randomized controlled trial

BACKGROUND: Non-communicable diseases (NCDs, e.g. cardiovascular disease) are responsible for high rates of morbidity and the majority of premature deaths worldwide. It is necessary to develop preventative interventions that can reduce the associated risk factors of NCDs. Researchers have found that the biomarker adrenomedullin (ADM) becomes elevated years before the onset of NCDs and might play a

Functional channel membranes for drinking water production

Drinking water production utilities rely on, among other processes, different filtration technologies like bank filtration and slow sand filters, as well as pressure, roughing, or rapid gravity filters that, together with low- and high-pressure operating membranes, help to ensure high quality drinking water for millions of customers all over the world. The global market of membrane separation tech

Reduced Prevalence of Severe Intraventricular Hemorrhage in Very Preterm Infants Delivered after Maternal Preeclampsia

Background: Very preterm (VPT) delivery after severe preeclampsia (PE) has been associated with adverse perinatal outcome. It is unclear whether fetal exposure to PE per se modifies the prevalence of neonatal morbidities associated with VPT birth. Objectives: To evaluate neonatal morbidity in VPT infants exposed to maternal PE compared to morbidity in nonexposed VPT infants. Methods: This retrospe