Recombinant adeno-associated virus serotype 2 (rAAV2) vector has been widely employed for gene therapy. Recent progress suggests that the new serotypes of AAV showed a better performance than did AAV2 in normal tissues. Here, we evaluate the potential role of human vascular endothelial growth factor (VEGF) gene transfer using rAAV vector pseudotyped with serotype I capsid proteins (rAAV1) in the t

The nitrate reductase activity (NRA) was measured during spring, early summer and late summer in three deciduous forests, where the tree layer was dominated by oak. The nitrate assimilation capacities of the compartments of the above-ground and below-ground biomass of the understory and of the leaves and roots of the tree layer were calculated as NRA per unit biomass and NRA per unit area. The NRA

The thesis analyzes the everyday life of women and men in a neighbourhood planned for low-income housing in the ourskirts of the capital San José in Costa Rica. The research uses an everyday life perspective and shows how gender organization leads to a division of labour and a use of space that differentiate between women and men's activities. There are space use patterns that reflect the existing

Raloxifene treatment has been shown to reduce the risk of vertebral fractures and breast cancer in postmenopausal women. The long-term economic implications of treatment with raloxifene have not yet been investigated. The aim of this study was to assess the cost-effectiveness of treating postmenopausal women in the UK with raloxifene. A previously developed computer simulation model was used to es

We studied the role of arachidonic acid metabolites, histamine, and 5-HT in airway responses to trimellitic anhydride (TMA) in actively sensitized guinea pigs. Sensitization was produced by two intradermal injections of free TMA (0.1 ml of 0.3% TMA in corn oil). After 21 to 28 days, guinea pigs were anesthetized and challenged with intratracheal instillation of 0.5% TMA conjugated to guinea pig se

Artikeln diskuterar händelser i och omkring Sövde i samband med det "Skånska upproret" 1180-81. I Sövde fanns från 1100-talet och fram till reformationen fanns en befäst huvudgård tillhörande ärkesätet i Lund. Spåren efter denna anläggning kom att undersökas år 1911 av pastor loci Oscar Blomstergren under överinseende av Otto Rydbeck, docent i nordisk konstarkeologi, Lund.

A series of bioassay experiments were performed from spring to autumn in a small dimictic lake (Deep Pond, Massachusetts) to examine the potential for bacterial growth limitation by organic carbon (glucose), inorganic nutrients (ammonium or phosphate), or both. The experiments demonstrated that phosphorus was the primary element limiting bacterial growth in Deep Pond during a large part of the sum

Antibodies to double-stranded (dsDNA) are associated with systemic lupus erythematosus (SLE) and directly involved in human lupus nephritis. Information about their glomerular target antigens is inconsistent, and whether availability of target antigens, antibody specificity or avidity are nephritogenic parameters, is not determined. In this study, we analyzed renal tissue from anti-dsDNA antibody-

By observing and analyzing the influence of the therapist on the family as well as interactions between family members, the encounter with a family in a medical setting can serve to improve the health of its members, by improving their ability to use their own resources. This method of focusing on the interaction between individuals in a family or other systems has been a valuable addition to medi

Abstract is not available

The article pins down problems of urbanization, poverty, and youth at risk, focusing on the situation of young women in African slums.

Twenty patients who underwent early aneurysm surgery--that is, surgery within 72 hours after rupture--underwent further follow-up examination including magnetic resonance imaging (MRI) of the brain and a comprehensive neuropsychological assessment. Significant statistical correlation between tissue loss as seen on a late MRI scan and neurobehavioral deficits could not be established. Among 9 patie