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Real-world effectiveness of osteoporosis treatment in the oldest old

Summary: We studied effectiveness of osteoporosis treatment in women older than 80 years, who often are not included in clinical trials. Treatments were as effective on bone density and fractures as in younger women. Introduction: To study real-world effectiveness of osteoporosis treatment on BMD and fractures in the oldest old women (≥ 80 years) compared with women (60–79 years) in the clinical s

Psychometric evaluation of the Swedish Quality of Dyadic Relationships scale – homogeneity and construct validity

Rationale and aims: The Quality of Dyadic Relationships is a self-assessment scale used to evaluate various aspects of relationship quality. Psychometric evaluation by the developers of the instrument has led to a nontested amended version. Further psychometric testing is thus warranted, and the aim of this study was to evaluate homogeneity, construct validity (in terms of concurrent, discriminant

Bicycle Traffic Volume Estimation Based on GPS Data

All the analytic methods for assessing the safety or comfort of bicyclists in urban area have as a common factor the number of bicycles that enter the system in a certain time interval or an estimate of that. The estimation of the average bicycle volume based on manual and automatic measurements is time-consuming and often require the use of expensive technology. The paper presents a method of est

The incretin effect in female mice with double deletion of GLP-1 and GIP receptors

To establish the contribution of glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) for the incretin effect after oral glucose, studies were undertaken in female mice with genetic deletion of receptors for GIP and GLP-1 (double incretin receptor knockout [DIRKO] mice) and their wild-type (WT) counterparts. Insulin secretion was explored after oral glucose (doses

Communication ability and communication methods in children with cerebral palsy

Aim: To investigate if communication ability and method were related to each other and to age, sex, gross motor function, or manual ability in children with cerebral palsy. Method: This cross-sectional study used data registered in the Swedish Cerebral Palsy Surveillance Program registry, involving 3000 children aged 0 to 18 years. Pearson’s χ2 test and Spearman’s correlation were used to test ass

Synthesis and experimental study of novel double perovskite Ba2NixCo2−xO6 as promising oxygen carrier materials for CO2 capture application

Novel oxygen-deficient double-perovskite type oxide Ba2NixCo2−xO6 was applied to produce O2/CO2 mixed stream gas for oxyfuel combustion application. A series of different Co concentration substituted Ba2NixCo2−xO6 was synthesized by an EDTA-citrate sol-gel combustion method. The oxygen carriers, Ba2Ni0.25Co1.75O6, Ba2Ni0.45Co1.55O6, Ba2Ni0.65Co1.35O6 and Ba2Ni0.85Co1.15O6 were c\characterized by s

Diagnosis of Gestational Diabetes Mellitus with Point-of-Care Methods for Glucose versus Hospital Laboratory Method Using Isotope Dilution Gas Chromatography-Mass Spectrometry as Reference

Background. In Sweden, both glucose analyzers in accredited laboratories and point-of-care glucose devices are used for gestational diabetes mellitus (GDM) diagnosis. The aim of this study was to compare the diagnostic performance of the HemoCue Glucose 201+ (HC201+) and RT (HC201RT) systems with that of the hospital central laboratory hexokinase method (CL) based on lyophilized citrate tubes, usi

#50+ fashion Instagram influencers : cognitive age and aesthetic digital labours

Purpose: This paper demonstrates how #50+ fashion Instagram influencers contribute to the social construction of cognitive age through their aesthetic digital labours. Design/methodology/approach: Non-participative netnography was used in the form of visual and textual analysis of over 300 Instagram posts including images, captions and comments. Findings: Findings reveal how outfit selection, back

Diagnostic Stability of Mild Cognitive Impairment, and Predictors of Reversion to Normal Cognitive Functioning

Objective: Studies that investigate predictive factors for spontaneous recovery (reversion) from mild cognitive impairment (MCI) are only beginning to emerge, and the long-term course of MCI is not properly understood. We aimed to investigate stability of the MCI diagnosis, predictors for reversion, as well as the trajectory of MCI over the course of 12 years. Materials and Methods: Data were draw

A Quantitative Analysis of the Role of Oxygen Tension in FLASH Radiation Therapy

Purpose: Recent demonstrations of normal tissue sparing by high-dose, high-dose-rate FLASH radiation therapy have driven considerable interest in its application to improve clinical outcomes. However, significant uncertainty remains about the underlying mechanisms of FLASH sparing and how deliveries can be optimized to maximize benefit from this effect. Rapid oxygen depletion has been suggested as

Oral provocation of patients allergic to sesquiterpene lactones with German chamomile tea to demonstrate possible systemic allergic dermatitis

Background: Most patients with contact allergy to Asteraceae plants are patch test positive to sesquiterpene lactone mix (SLM). There are several reports among these patients of a flare-up of hand eczema after ingestion of food and beverages originating from Asteraceae plants. Aim: To investigate whether German chamomile tea can elicit systemic allergic dermatitis. Patients and Methods: Individual

Being Different but Striving to Seem Normal : The Lived Experiences of People Aged 50+ with ADHD

This qualitative study explored the day-to-day life of people aged 50+ diagnosed with ADHD. A phenomenological-hermeneutical method was chosen for the analysis. Two themes including sub-themes were revealed. The first theme, Being different and trying to handle my inner self, concerned emotional self-regulation, emotional resilience, social skills, and personal resource management. The second them

Hypoxia-induced release, nuclear translocation, and signaling activity of a DLK1 intracellular fragment in glioma

Glioblastoma multiforme is characterized in part by severe hypoxia associated with tumor necrosis. The cellular response to hypoxia can influence several properties of tumor cells associated with aggressive tumor growth, including metabolic adaptations and tumor cell migration and invasion. Here, we found that Delta Like Non-Canonical Notch Ligand 1 (DLK1) expression was elevated as compared with

Investigating information seeking in ravens (Corvus corax)

Measuring the responses of non-human animals to situations of uncertainty is thought to shed light on an animal’s metacognitive processes; namely, whether they monitor their own knowledge states. For example, when presented with a foraging task, great apes and macaques selectively seek information about the location of a food item when they have not seen where it was hidden, compared to when they

Differential gene expression of Plasmodium homocircumflexum (lineage pCOLL4) across two experimentally infected passerine bird species

Plasmodium parasites are present in a wide range of host species, some of which tend to be more susceptible than others, potentially as an outcome of evolved tolerance or resistance. Common starlings seem to cope with malaria infection while common crossbills are more susceptible to the same infections. That raises the question if the parasites rely on the same molecular mechanisms regardless of h