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Timing and climate forcing of volcanic eruptions for the past 2,500 years

Volcanic eruptions contribute to climate variability, but quantifying these contributions has been limited by inconsistencies in the timing of atmospheric volcanic aerosol loading determined from ice cores and subsequent cooling from climate proxies such as tree rings. Here we resolve these inconsistencies and show that large eruptions in the tropics and high latitudes were primary drivers of inte

An amperometric enzyme biosensor for real-time measurements of cellobiohydrolase activity on insoluble cellulose

An amperometric enzyme biosensor for continuous detection of cellobiose has been implemented as an enzyme assay for cellulases. We show that the initial kinetics for cellobiohydrolase I, Cel7A from Trichoderma reesei, acting on different types of cellulose substrates, semi-crystalline and amorphous, can be monitored directly and in real-time by an enzyme-modified electrode based on cellobiose dehy

APC-PCI complex levels for screening of AAA in patients with peripheral atherosclerosis.

To evaluate the use of activated protein C-protein C inhibitor (APC-PCI) complex levels for detection of abdominal aortic aneurysm (AAA) in patients with peripheral atherosclerotic disease (PAD). APC-PCI levels and aortic diameter evaluated in 511 PAD patients without previously known AAA followed-up concerning survival for 4.8(0.5) years. AAA was found in 13 % of patients. Aortic diameter correla

Smoking and Chronic Pain Among People Aged 65 Years and Older.

OBJECTIVE: To study the relationship between smoking and chronic pain among people aged 65+ years. DESIGN: A cross-sectional study. SAMPLE: The study was carried out in 2011 and included a randomly selected (N = 2000, response rate 57%) sample of people aged 65 years and older, living in Sweden. MEASUREMENT: A postal questionnaire with questions about demographic data, living conditions, tobacco u

Methods for the preparation of chlorophyllide a: an intermediate of the chlorophyll biosynthetic pathway

Chlorophyllide a is a metabolite late in the biosynthesis of chlorophylls and bacteriochlorophylls. Isolation procedures for chlorophyllide a from Rhodobacter capsulatus CB1200 and barley (Hordeum vulgare L.) are described and compared. R. capsulatus CB1200 is a double mutant in the bacteriochlorophyllide a biosynthetic pathway, and chlorophyllide a is excreted by the cells when grown in Tween 80-

Contrasting diversity patterns of epigeic arthropods between grasslands of high and low agronomic potential

Abstract in UndeterminedIncreasing demand for food, fuel and fibre promotes the intensification of land-use, particularly in areas favourable for agricultural production. In less-favourable areas, more wildlife-friendly farming systems are often either abandoned or under pressure of conversion, e.g. for bioenergy production. This raises the question, to which extent areas of different agronomicpot

Word tones cueing morphosyntactic structure: Neuroanatomical substrates and activation time-course assessed by EEG and fMRI.

Previous studies distinguish between right hemisphere-dominant processing of prosodic/tonal information and left-hemispheric modulation of grammatical information as well as lexical tones. Swedish word accents offer a prime testing ground to better understand this division. Although similar to lexical tones, word accents are determined by words' morphosyntactic structure, which enables listeners t

The Experience of GPU Calculations at Lunarc

To meet the ever increasing demand for computational speed and use of ever larger datasets, multi GPU installations look very tempting. Lunarc and the Theoretical Astrophysics group at Lund Observatory collaborate on a pilot project to evaluate and utilize multi-GPU architectures for scientific calculations. Starting with a small workshop in 2009, continued investigations eventually lead to the pr

MicroRNAs: new biomarkers and therapeutic targets after cardiac arrest?

Despite advances in resuscitation medicine, including target temperature management as part of postcardiac arrest care, many patients will have a poor neurological outcome, most often resulting in death. It is a commonly held belief that the ability to prognosticate outcome at an early stage after cardiac arrest would allow subsequent health care delivery to be tailored to individual patients. How

Chemoenzymatic Deracemization of Secondary Alcohols by using a TEMPO-Iodine-Alcohol Dehydrogenase System

A deracemization system for secondary alcohols was established after the analysis of individual steps and their compatibility in one pot. The chemical oxidation and bioreduction occurred in a sequential manner to yield 1-arylethanols and lineal aliphatic alcohols with excellent conversions and enantiomeric excess values. The oxidation step was performed by using 2,2,6,6-tetramethylpiperidin-1-oxyl

An improved course of glycaemia after a bread based breakfast is associated with beneficial effects on acute and semi-acute markers of appetite.

The prevalence of type 2 diabetes mellitus is rapidly increasing all over the world and a diet promoting reduced glycaemic excursions in the postprandial phase may help to prevent the disease. In the present study guar gum (GG) and whole grain rye flour or high amylose maize starch (HAM) was combined to design bread products giving low and sustained glycaemia. A meal study was performed with young

Metabolic syndrome and psychiatrists' choice of follow-up interventions in patients treated with atypical antipsychotics in Denmark and Sweden

Introduction: The aim of the present study was to obtain point prevalence estimates of the metabolic syndrome according to the NCEP III criteria in a sample of patients with schizophrenia spectrum disorders treated with atypical antipsychotic drugs in Denmark and Sweden, and to assess the psychiatrists' choice of recommendations for follow-up interventions based on the patients' laboratory results

Dissolution driven crack branching in polycarbonate

Stress corrosion, in the form of chemically assisted crack growth, in polycarbonate is examined with focus on crack branching characteristics. Cracks with finite width are observed; this is to be expected for dissolution driven cracking. The cracks branched repeatedly and crack widths before and after branching are measured. Both symmetric and asymmetric branching is found. The dissolution rate is

Grading breast cancer tissues using molecular portraits.

Tumor progression and prognosis of breast cancer patients is difficult to assess using current clinical and laboratory parameters, where a pathological grading is indicative of tumor aggressiveness. This grading is based on assessment of nuclear grade, tubule formation, and mitotic rate. We report here the first protein signatures associated with histological grades of breast cancer, using a novel

A winning strategy? The employment of women and firm longevity during industrialisation

Why do certain firms prosper and grow old while other firms fail? Established knowledge tells us that longevity is related to the firm's ability to adapt to market conditions, through product diversification, learning-by-doing and adopting new strategies regarding technology, human resources and management. By estimating duration models using new data covering the entire Swedish tobacco industry,

Keeping It Steady. Older Adults Perform More Consistently on Cognitive Tasks Than Younger Adults

People often attribute poor performance to having bad days. Given that cognitive aging leads to lower average levels of performance and more moment-to-moment variability, one might expect that older adults should show greater day-to-day variability and be more likely to experience bad days than younger adults. However, both researchers and ordinary people typically sample only one performance per