This thesis concerns a novel alkaline protease produced by an extremophilic microbial specie, designated as AL20, isolated from a feather sample collected at the shore of the alkaline soda lake Abjata in the Ethiopian Rift Valley. The isolate is a heterotrophic, alkaliphilic, halotolerant gram-positive, strictly aerobic, non-motile, non-spore forming bacterium. The organism grew at 37°C, pH 10, an

Today’s cloud data center infrastructures are not even near being able to cope with the enormous and rapidly varying capacity demands that will be reality in a near future. So far, very little is understood about how to transform today’s data centers (being large, power-hungry facilities, and operated through heroic efforts by numerous administrators) into a self-managed, dynamic, and dependable i

Alzheimer’s disease (AD) is an age-related, irreversible brain disorder that occurs gradually and results in memory loss, behavioural and personality changes. The disease is characterized by an abnormal accumulation of amyloid-beta (Ab) peptide in the extracellular space and the protein Tau within nerve cells of certain regions of the brain. Aâ1-42 is a major component of amyloid deposits in AD, b

Popular Abstract in Swedish Svenska knäplastikregistret och knäledsoperation med enkammarprotes av Stefan Lewold Ledsjukdom, oftast artros, är den vanligaste kroniska åkomman hos äldre. Dess orsak är oftast inte känd och någon förebyggande behandling finns inte. Icke operativ behandling kan i tidiga stadier dämpa symptomen men då sjukdomen fortskrider får patienten allt svårare att klara sig. GenThe Swedish Knee Arthroplasty study has prospectively registered and followed knee arthroplasties done in Sweden since 1976. Demography, epidemiology and general knee prosthetic biofunction is given for 30,003 primary knee arthro-plasties and their revisions through 1992. The annual number of knee arthroplasties increased fourth fold while the relative use of Unicompartmental knee arthroplasty (UK

Abstract not available

Affinity two-phase partitioning based on an immunoaffinity sandwich approach for the rapid and selective purification of membranes is presented in this thesis. The method was developed by studying different parameters governing the affinity partitioning of model membranes. To this end, biotinylated liposomes were used. They specifically distributed to the bottom phase of a poly (ethylene glycol)/d

This paper assumes the availability of a very fast higher-dimensional rasterizer in future graphics processors. Working in up to five dimensions, i.e., adding time and lens parameters, it is well-known that this can be used to render scenes with both motion blur and depth of field. Our hypothesis is that such a rasterizer can also be used as a flexible tool for other, less conventional, usage area

Popular Abstract in Swedish Inom analytisk kemi används en rad metoder för att erhålla separation mellan de ämnen man vill studera. Detta är ofta nödvändigt om man vill ta reda på specifika egenskaper i ett biologiskt prov. Naturen har utvecklat sofistikerade verktyg t.ex. antikroppar som även kan användas för att separera ett specifikt ämne. Inom mitt doktorsarbete har antikroppar fyllt en viktigThe use of microdialysis sampling and flow immunochemical detection as well as MALDI-TOF MS for peptide and protein analysis is described. Sampling of peptides and smaller proteins was investigated with different membranes. Cyclodextrines additives and an on-line push-pull microdialysis sampling method was used with the result of a higher sampling efficiency compared to conventional microdialysis