Intra-islet crosstalk has become a focus area to fully understand the regulation of insulin secretion and impaired β-cell function in type 2 diabetes (T2D). Here, we put forward evidence for insulin-like growth factor binding protein 7 (IGFBP7) as a potential protein involved in autocrine and paracrine β-cell regulation. We showed presence of IGFBP7 in granules of both human α- and β-cells and mea

Politiska organisationer anställer ofta, och i allt högre utsträckning, utredare och andra kunskapsarbetare för att producera kunskap och politiska förslag, och den svenska fackliga centralorganisationen LO har sedan 1930-talet anställt nationalekonomer och andra samhällsvetare. Genom analys- och presentationsmetoder som liknar den akademiska samhällsvetenskapen, och genom interaktion med talesperPolitical organisations routinely, and increasingly, employ researchers to make knowledge claims and suggest political action. Swedish blue-collar trade union organisation LO has done so since the 1930s, employing economists and other social scientists drawing in part on methods of analysis and presentation similar to academic social science, and in part on interaction with spokespersons for trade

Many spatial audio applications, including active noise control, virtual reality, and the generation of individual sound zones, rely on an understanding of acoustic propagation. In room acoustics, which is the focus of this thesis,the sound field generated by a point source is typically modelled as a linear time-invariant system, described by its room impulse response (RIR). The RIR captures the r

En viktig del av utvecklingen av den fysiska butiken är nya koncept, både som ett sätt att spegla den digitala utvecklingen (med omnikanal som ambition) men också som ett sätt att spegla en förändrad värld där nya konsumentbehov etcetera spelar en viktig roll. Men klarar sig nya format om inte också sättet att utvärdera dem förändras? Den traditionella utvärderingen med försäljning som bas behöver

This research project aims to explore and theorize the role of the Market in a hyperviolence-endorsing consumer culture. How does the subaltern speak through “gangfluencers” in a Global North welfare society, and how do affective intensities of consumer desire enact the violent consumer subject herein?This research project aims to explore and theorize the role of the Market in a hyperviolence-endorsing consumer culture. How does the subaltern speak through “gangfluencers” in a Global North welfare society, and how do affective intensities of consumer desire enact the violent consumer subject herein?

In this conceptual paper we reimagine the Capitalocentric present. To do so, we (1) critique corporate fantasies about ethical consumption; (2) offer alternative relational ethics of consumption, with special attention to concrete neo-animist practices to imagine alternative futures to the Capitalocentric present, and (3) invite imaginative theorization as a bridge between present and future.In this conceptual paper we reimagine the Capitalocentric present. To do so, we (1) critique corporate fantasies about ethical consumption; (2) offer alternative relational ethics of consumption, with special attention to concrete neo-animist practices to imagine alternative futures to the Capitalocentric present, and (3) invite imaginative theorization as a bridge between present and future.

In this special session we wish to critique and reimagine the anthropocentric present. In contemporary consumerist society (Schmitt et al., 2022), the global “free market” is presented as the solution to the environmental and climate urgency through pillars like unlimited growth, responsibilized consumers, and not least, the domination of Nature (e.g. Hornborg 2019). There are alternatives, but thIn this special session we wish to critique and reimagine the anthropocentric present. In contemporary consumerist society (Schmitt et al., 2022), the global “free market” is presented as the solution to the environmental and climate urgency through pillars like unlimited growth, responsibilized consumers, and not least, the domination of Nature (e.g. Hornborg 2019). There are alternatives, but th

The entanglement of business and consumption practices have been neglected in prior consumer research. We address this issue by developing the concept lifestyled business practice. Through a study of criminal gangs in Sweden we contribute by developing three main entanglements of business practice; hedonic structures, stylized intelligence and sonic monetizationThe entanglement of business and consumption practices have been neglected in prior consumer research. We address this issue by developing the concept lifestyled business practice. Through a study of criminal gangs in Sweden we contribute by developing three main entanglements of business practice; hedonic structures, stylized intelligence and sonic monetization

Med denna guide vill vi ge forskningsbaserade råd om hur du kan minska dinklimatpåverkan genom att förändra dina levnadsvanor, och leva i linje medParisavtalets 1,5-gradersmål. Vi vill både visa svenskars genomsnittliga klimat-avtryck och den stora skillnaden mellan individers koldioxidavtryck. Det innebär attdet behövs olika vägval för de som vill förändra sina levnadsvanor. Guiden betonardessutoSyftet med denna guide är att ge forskningsbaserade råd om de mest effektiva sätten att minska sitt koldioxidavtryck för en genomsnittlig person i Sverige. Samtidigt visar den att individuella livsstilsförändringar måste kombineras med och stödjas av förändringar i det omgivande samhället. Dessutom ger guiden en allmän fingervisning om storleken på ditt koldioxidavtryck och om vilka delar av din v

Effective microbial bioprocessing relies on maintaining ideal cultivation conditions, highlighting the necessity for tools that monitor and regulate cellular performance and robustness. This study evaluates a fed-batch cultivation control system based on at-line flow cytometry monitoring of intact yeast cells having a fluorescent transcription factor-based redox biosensor. Specifically, the biosen

Somatic copy number variations (CNVs), including abnormal chromosome numbers and structural changes leading to gain or loss of genetic material, play a crucial role in initiation and progression of cancer. CNVs are believed to cause gene dosage imbalances and modify cis-regulatory elements, leading to allelic expression imbalances in genes that influence cell division and thereby contribute to can