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Enriched environment influences adrenocortical response to immune challenge and glutamate receptor gene expression in rat hippocampus

Housing of animals in an enriched environment (EE) has many positive effects on brain structure and function and can facilitate recovery from various brain injuries. The purpose of this study was to evaluate whether enriched rearing could alter the stress response induced by repeated immune challenge and to investigate the influence of EE and immune challenge on glutamate receptor gene expression

Psychosocial work conditions, social capital, and daily smoking: a population based study.

Objective: To investigate the associations between psychosocial conditions at work, social capital/social participation, and daily smoking. Design/setting/participants/measurements: The 2000 public health survey in Scania is a cross sectional postal questionnaire study with a 59% participation rate. A total of 5180 persons aged 18–64 years that belonged to the work force and the unemployed were i

Analysis of 5-hydroxy-N-methyl-2-pyrrolidone and 2-hydroxy-N-methylsuccinimide in plasma

A method for the determination of 5-hydroxy-N-methyl-2-pyrrolidone (5-HNMP) and 2-hydroxy-N-methylsuccinimide (2-HMSI) in plasma was developed. 5-HNMP and 2-HMSI are metabolites to the widely used organic solvent N-methyl-2pyrrolidone (NMP). The 5-HNMP and 2-HMSI were purified from plasma by C8 solid phase extraction, derivatised by bistrimethylsilyl trifluoroacetamid, and analysed by gas chromato

Morphometric and psychometric comparisons between non-substance-abusing patients with posttraumatic stress disorder and normal controls

BACKGROUND: Hippocampal decrease in size in response to posttraumatic stress disorder (PTSD) is still a subject of controversy. The aims of this study were to: (1) confirm previous hippocampus findings in PTSD patients compared to controls, using ethnically similar study groups where alcohol and drug abuse were non-existent; (2) test influence of disease duration as well as depression scores on po

Från ägarmakt under ansvar till företagsledarmakt. En studie över maktförskjutningen hos tre svenska verkstadsaktiebolag

The dissertation is confined to the formal work of the boards of the parent companies as recorded in the approved minutes of meetings at Alfa Laval AB, Atlas Copco AB and Kockums Mekaniska Verkstads AB and is based on the Companies Law applying in Sweden since 1848. The study covers the time from the establishment of the joint stock company up to the ordinary general meeting of 1980 (1979 in the c

Low-Dose Prostacyclin Improves Cortical Perfusion following Experimental Brain Injury in the Rat.

It was recently shown that prostacyclin at a low dose reduces cortical cell death following brain trauma in the rat. Conceivably, prostacyclin with its vasodilatory, anti-aggregatory, anti-adhesive and permeability-reducing properties improved a compromised perfusion caused by post-traumatic vasoconstriction, microthrombosis and increased microvascular permeability. The objective of the present st

Exploiting the vascular protective effects of high-density lipoprotein and its apolipoproteins - An idea whose time for testing is coming, Part II

Despite the benefits of currently available preventative and therapeutic interventions, atherosclerotic vascular disease continues to be a major cause of morbidity and mortality in much of the Western World. This emphasize,,, the need for additional preventive and therapeutic interventions exploiting new targets to compliment and augment the results of LDL lowering and other current strategies. On

Influence of ATP, ADP and AMPPNP on the energetics of contraction in skinned smooth muscle

The contraction of smooth muscle is influenced by the substrate MgATP and the product MgADP. The effects on force, shortening velocity and ATP-turnover, are consistent with an influence on the kinetics of cross-bridge cycling. Part of these effects are mediated via an influence on the regulation of contraction by myosin light chain phosphorylation. Results from preparations activated by thiophosph

Autologous chondrocyte transplantation - Biomechanics and long-term durability

We evaluated the durability of autologous chondrocyte transplantation grafts in 61 patients treated for isolated cartilage defects on the femoral condyle or the patella and followed up for a mean of 7.4 years (range, 5 to 11). Durability was determined by comparing the clinical status at the long-term follow-up with that found 2 years after the transplantation. After 2 years, 50 of the 61 patients

Improvement of Texture by Modifying Processing Conditions

Fruit and vegetable processors, faced with the challenge of gaining and maintaining a healthy position in the competitive fruit and vegetable sector, are optimising traditional processes towards product quality. Using frozen potatoes as a case study, the aim of this study was to evaluate the potential of improving the texture of potatoes by modifying the processing conditions. The texture of proce

Reef biostromes and related facies from the Middle Silurian of Gotland, Sweden

Reef biostromes and related facies from the upper part of Wenlock and from Ludlow were investigated in order to account for their formation, their palaeoecology and biology. In the Hemse Group of Ludlow age, all studied biostromes comprise a low diversity fauna where one or few species dominates. These biostromes are divided into Kuppen type biostromes, Grogarnshuvud type biostromes and Sjaustreha