The 'thrifty phenotype' hypothesis proposed that fetal undernutrition increases risk of diabetes in later life. Undernourished low birthweight Indian babies are paradoxically more adipose compared to well-nourished European babies, and are at higher risk of diabetes in later life. Twin pregnancies are an example of in utero growth restrictive environment due to shared maternal nutrition. There are

Wastewater infrastructure has a long lifetime and is subject to changing conditions and demands. When plans are made to upgrade or build new infrastructure, transdisciplinary planning processes and a robust analysis of future conditions are needed to make sustainable choices. Here, we provide a stepwise collaborative planning process in which future scenarios are developed together with local stak

Decreased heart levels of nitric oxide (NO) and hydrogen sulfide (H2S) in type 2 diabetes (T2D) are associated with a higher risk of mortality following ischemia-reperfusion (IR) injury. This study aimed to determine the effects of co-administration of sodium nitrite and sodium hydrosulfide (NaSH) on IR injury in the isolated heart from rats with T2D. Two-month-old male rats were divided into 5 gr

Följande text är en enkel redovisning av svaren på frågor om begravning i frågelistan Kyrklig sed 2008-2009, som Lunds Universitets Kyrkohistoriska Arkiv (LUKA) sände till alla pastorat i Svenska kyrkan i september 2009. Av flera skäl, mer om detta nedan, kommer jag inte att jämföra hur man i pastoraten i de olika stiften svarade på frågorna. Istället kommer jag att peka på de stift som har högst

Fetal and adult hematopoietic stem and progenitor cells (HSPCs) are characterized by distinct redox homeostasis that may influence their differential cellular behavior in normal and malignant hematopoiesis. In this work, we have applied a quantitative mass spectrometry-based redox proteomic approach to comprehensively describe reversible cysteine modifications in primary mouse fetal and adult HSPC

What is degrowth and what are its implications for political economy? Divided in three parts, this dissertation explores the why, what, and how of degrowth.The first part (Of growth and limits) studies the nature, causes, and consequences of economic growth. Chapter 1: Understanding economic growth answers a series of questions about the nature of economic growth: What is it exactly that grows? By

Degrowth – the planned and democratic reduction of production and consumption as a solution to the social-ecological crises – is slowly making its way to the sphere of policy-making. But there is a problem: proposals are scattered through a voluminous literature, making it difficult for decision-makers to pinpoint the concrete changes associated with the idea of degrowth. To address this issue, we

Co-infections with bacterial or fungal pathogens could be associated with severity and outcome of disease in COVID-19 patients. We, therefore, used a 16S and ITS-based sequencing approach to assess the biomass and composition of the bacterial and fungal communities in endotracheal aspirates of intubated COVID-19 patients. Our method combines information on bacterial and fungal biomass with communi