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Hyperbolic systems with relaxation: characterization of stiff well-posedness and asymptotic expansions

The Cauchy problem for linear constant-coefficient hyperbolic systems ut + ∑j A(j)uxj = (1/δ)Bu + Cu in d space dimensions is analyzed. Here (1/δ)Bu is a large relaxation term, and we are mostly interested in the critical case where B has a non-trivial null-space. A concept of stiff well-posedness is introduced that ensures solution estimates independent of 0 < δ 1. Stiff well-posedness is charact

MACIS: Minimisation of and Adaptation to Climate Change Impacts on BiodiverSity

The recently finished EU funded project MACIS reviewed observed and projected climate change impacts on biodiversity. It assessed mitigation and adaptation options. It also reviewed and developed methods to assess future impacts of climate change on biodiversity including the identification of policy options to prevent and minimise these impacts.

Murine monoclonal antibodies against murine uPA receptor produced in gene-deficient mice: inhibitory effects on receptor-mediated uPA activity in vitro and in vivo

Binding of urokinase plasminogen activator (uPA) to its cellular receptor, uPAR, potentiates plasminogen activation and localizes it to the cell surface. Focal plasminogen activation is involved in both normal and pathological tissue remodeling processes including cancer invasion. The interaction between uPA and uPAR therefore represents a potential target for anti-invasive cancer therapy. Inhibit

Videofluoroscopic swallow study: techniques, signs and reports.

Management of oropharyngeal swallowing dysfunction often requires both a clinical and an instrumental examination. A videofluoroscopic swallowing study is an instrumental examination that often could be a good option and a very useful tool for the swallowing clinician. At Skåne University Hospital, Malmö, Sweden, the name of such examination is therapeutic videoradiographic swallowing study (TVSS)

Modelling a Duaul-fuelled Multi-cylinder HCCI Engine Using a PDF based Engine Cycle Simulator

Operating the HCCI engine with dual fuels with a large difference in auto-ignition characteristics (octane number) is one way to control the HCCI operation. The effect of octane number on combustion, emissions and engine performance in a 6-cylinder SCANIA truck engine, fuelled with n-heptane and isooctane, and running in HCCI mode, are investigated numerically and compared with measurements taken

Parents' Experiences of Health and Needs When Supporting Their Adolescents With Cerebral Palsy During Transition to Adulthood.

Parents are the primary support providers for adolescents with disabilities, their health and wellbeing is therefore of great importance when planning for youths' transition into adulthood. The aim of this study was to gain a deeper understanding of how parents of adolescents with cerebral palsy (CP) experience their own health and wellbeing and their needs for support during the adolescent's tran

The islet enhancer vildagliptin: mechanisms of improved glucose metabolism.

Vildagliptin is a potent, selective and reversible inhibitor of dipeptidyl peptidase-4 (DPP-4), the enzyme responsible for rapid inactivation of the incretin hormones glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP). GLP-1 and GIP are important for the maintenance of normal glucose homeostasis as they enhance the sensitivity of insulin (beta-cell) and glucagon (alpha-cell)

En liten hand

Regular column on performing arts in the weekly newspaper Arbetaren (The Worker).

Sex-specific interactions between the IRS1 polymorphism and intakes of carbohydrates and fat on incident type 2 diabetes.

BACKGROUND: The minor T allele of rs2943641 near the gene encoding for insulin receptor substrate 1 (IRS1) has been associated with decreased risk of type 2 diabetes (T2D) and adiposity in genome-wide association studies. Dietary intake can influence the regulation of IRS1, and studies have indicated sex-specific associations between IRS1 and adiposity. OBJECTIVE: The objective was to examine the

Soft x-ray ionization and fragmentation of n- and iso-propanol

Threshold electron and total ion yield spectra are presented for the near C and O 1s edge photoexcitation of n- and iso-propanol. To our knowledge these are the first such data for iso-propanol, and represent the first direct measurement of the core ionization energies of these molecules by threshold photoelectron spectroscopy. In particular, the C 1s energies for n-propanol are found to be lower

Laparoscopic extended pelvic lymphadenectomy for staging can be performed with limited morbidity and short hospital stay in patients with prostate cancer.

Objective: Assessing lymph-node status in prostate cancer patients with high accuracy is only possible with surgical staging, despite the evolution of modern imaging techniques. The use of surgical staging has to be balanced against the complications of the procedure, the individual patient's risk for harbouring metastasesand the consequences for the treatment of the patient if such metastases are

High RBM3 expression in prostate cancer independently predicts a reduced risk of biochemical recurrence and disease progression.

BACKGROUND: High expression of the RNA-binding protein RBM3 has previously been found to be associated with good prognosis in breast cancer, ovarian cancer, malignant melanoma and colorectal cancer. The aim of this study was to examine the prognostic impact of immunohistochemical RBM3 expression in prostate cancer. FINDINGS: Immunohistochemical RBM3 expression was examined in a tissue microarray

Experimental determination of dose conversion coefficients for external radiation exposure with gamma emitting radionuclides

Abstract in Russian В данной работе был использован фантом Алдерсон-РАНДО для экспериментального определения коэффициентов перехода для условий внешнего облучения. Были смоделированы следующие конфигурации облучения: ротационная геометрия облучения с использованием различных точечных источников (99mTc, 131I + 133Ba, 137Cs, 60Co); передне-задняя и задне-передняя геометрия облучения источником 137CsIn the present paper the Alderson RANDO phantom have been used to experimentally determine conversion coefficients. A limited number of exposure situations were investigated for this purpose: rotational-geometry with different radiation point sources (99mTc, 131I+133Ba, 137Cs, 60Co), AP- and PA-geometry with 137Cs and a special pocket-geometry with 137Cs. All experiments were carried out on a larg