Here, we characterize a subset of ILC3s that express Neuropilin1 (NRP1) and are present in lymphoid tissues, but not in the peripheral blood or skin. NRP1+ group 3 innate lymphoid cells (ILC3s) display in vitro lymphoid tissue inducer (LTi) activity. In agreement with this, NRP1+ ILC3s are mainly located in proximity to high endothelial venules (HEVs) and express cell surface molecules involved in

I det här papret undersöker jag vilka föreställningar om etnicitet och kön som professionella yrkesgrupper (lärare, boendecoacher, socialsekreterare, barn- och ungdomshandläggare) ger uttryck för i sitt arbete med asylsökande ungdomar. Jag undersöker också hur detta präglar deras arbete med ungdomarna och konsekvenserna av detta. Ungdomarna, samtliga pojkar och analfabeter, deltar i språkintrodukt

The impact of hydrostatic pressure on magnetic anisotropy energies in (Ga, Mn)As thin films with in-plane and out-of-plane magnetic easy axes predefined by epitaxial strain was investigated. In both types of sample we observed a clear increase in both in-plane and out-of-plane anisotropy parameters with pressure. The out-of-plane anisotropy constant is well reproduced by the mean-field p-d Zener m

A novel design of alkali chloride vapour-generating cell has been developed, which can serve as a calibration cell for quantitative ultraviolet absorption concentration measurements and meticulous spectral investigations of alkali compounds. The calibration cell was designed to provide alkali vapour of well-controlled concentrations and temperatures, and consisted of a sealed quartz cell measuring

Two different solutions for the characteristic modes (CMs) of lossy structures were previously developed using induced volume currents. The first solution diagonalizes the scattering and perturbation matrices, guaranteeing far-field orthogonality at the cost of imaginary eigenvalues and eigencurrents. The second solution does not perfectly diagonalize these matrices, but maintains real-valued eige

Antenna current optimization is used to determine optimal currents in the antenna design region. The currents provide understanding, physical bounds, and figures of merits for antenna designs. The problem is formulated as a convex optimization problem expressed in the currents on the antenna structure. These convex optimization problems are solved with a computational cost comparable to a Method o

The requirement of higher data rates and the emergence of new wireless device demands in future 5G communication put millimeter-wave frequencies in focus. To investigate electromagnetic-filed exposure at such frequencies for 5G cellular phone application, a planar near-field antenna measurement system is established. A tapered open-ended rectangular waveguide was used as the probe antenna, and a p

Requirements Engineering has recently been greatly influenced by the way how firms use Open Source Software (OSS) and Software Ecosystems (SECOs) as a part of their product development and business models. This is further emphasized by the paradigm of Open Innovation, which highlights how firms should strive to use both internal and external resources to advance their internal innovation and techn

This report describes a method developed for the synthesis of computer algorithms for optimal steady state control of dynamic, industrial processes with unknown characteristics -- a procedure involving automated model construction. Also included is a discussion of how the method was applied to the construction of control laws for steady state control of basis weight, moisture content and refining

Two adaptive autopilots for ships are designed, The autopilots are based on velocity scheduling, a self-tuning regulator for steady state course keeping, a high gain turning regulator with variable structure and a Kalman filter.Methods for design of the autopilots are discussed. Results from simulations and full-scale experiments with three different tankers are presented. The autopilots are shown

The β2-integrins on leukocytes can serve as a signaling unit during cell adhesion and locomotion, and to further clarify this important property we investigated the possible mechanisms of β2-integrin-induced activation of PtdIns 3-kinase. It has previously been demonstrated that clustering of β2-integrins activates p21(ras) by a tyrosine kinase-dependent pathway, and here we show that active p21(r

Integrin dependent adhesion and dynamic modulations of the actin network are prerequisites for normal cell locomotion. To investigate whether the actin microfilamentous system does play a role in regulation of β2-integrin-induced signalling, we pretreated granulocytes with staurosporine, a well-known protein kinase inhibitor that has also been shown to disrupt the cytoskeleton of intact cells. Pre

Abstract: Bladder cancer is a heterogenous disease, ranging from minimally invasive, low-grade tumours with lowrecurrence rates and mortality on one end of the spectrum, and muscle invasive, high-grade disease prone torecurrence, progression and death at the other end.The aim of this thesis was to investigate the expression, clinicopathological correlates and prognostic significanceof the candidat

Background and Purpose: Leukocytes have been implicated in the development of ischemia atherosclerotic vascular disease. In a prospective study we investigated whether the plasma concentration of inflammatory mediator, ie, proteases and cytokine, as markers for systemic leukocyte activation, are increased in patient with acute ischemic cerebrovascular diseases. Methods: Using enzyme-linked immunos