In this thesis three general problems concerning construction of evolutionary trees are considered. Algorithms for the problems are presented and the complexity of the problems is investigated. The thesis consists of three corresponding parts. The first part is devoted to the problem of constructing evolutionary trees in the experiment model. Different algorithms for the problem are given, includ

The antithrombotic effect of bovine activated protein C (bAPC) given with or without bovine protein S (bPS) was investigated in a rat model of deep arterial injury. A segment of the left common carotid artery was isolated between vascular clamps and opened longitudinally. An endarterectomy was performed and the arteriotomy was closed with a running suture, whereafter the vessel was reperfused by r

Previous work has shown that the lips are moving at a high velocity when the oral closure occurs for bilabial stop consonants, resulting in tissue compression and mechanical interactions between the lips. The present experiment recorded tongue movements in four subjects during the production of velar and alveolar stop consonants to examine kinematic events before, during, and after the stop closur

Let $\Omega$ be a domain in ${\bf C}$. A point $\lambda$ of the boundary of $\Omega$ is said to be essential if, for every neighborhood $V$ of $\lambda$, there is an $f\in H^\infty(\Omega)$ such that $f$ does not extend analytically to $V$. It is known that there is a smallest domain $\Omega^*$ containing $\Omega$ such that $\Omega^*$ has no nonessential boundary points. The main result here is th

This thesis contains two parts. The first part deals with a stochastic impulse control problem, subject to the restriction of a minimum time lapse in between interventions made by the controller. We prove existence of an optimal control and show that the value function of the control problem satisfies a system of quasi-variational inequalities. Furthermore, we apply the control method to pri

Research shows that there are often problems with cooperation between rehabilitation professionals within vocational rehabilitation. The aim of this study was to describe employers' experiences of how cooperation between different rehabilitation professionals can be improved in a vocational rehabilitation planning process. Ten employers who had sent their employees to vocational rehabilitation at

The development of new generic technologies occurs within traditional structures of industry - government interaction, but also unleashes a process of 'creative destruction' generating new institutional patterns. This article, focusing on biotechnology, describes and compares policy processes and institutional arrangements in Australia and Sweden. The Swedish biotechnology sector displays a patter

We investigate the performance of overload control through queue length for two different web server architectures. Both of them use finite queue lengths to prevent servers from being overloaded. One architecture prioritizes requests from established sessions while the other treats all requests equally. First, we introduce queueing models for these two systems. Then, we define and explain a new we

Background Now lung volume reduction surgery (LVRS) has become one of the most effective methods for the management of some cases of severe chronic obstructive pulmonary disease (COPD). We evaluated the mid-term effects of LVRS on pulmonary function in patients with severe COPD. Methods Ten male patients with severe COPD aged 38-70 years underwent LVRS and their pulmonary function was assessed bef

Bacillus subtilis can synthesise cytochromes containing a-, b-, c- and d-type heme. The biosynthetic pathways of these heme prosthetic groups were investigated by using strains blocked in uroporphyrinogen III synthesis from porphobilinogen or in heme b (protoheme IX) synthesis from uroporphyrinogen III. The results strongly suggest that heme a and heme d are both synthesised from heme b (protoheme

The power amplifier tends to be one of the most demanding parts to fully integrate when building an entire radio on a CMOS chip. In this paper the design of a fully integrated RF power amplifier without inductors is described. As inductors in CMOS technology are associated with various problems, it is interesting to examine what performance can be achieved without them. An amplifier with an operat

Peptides spanning the entire, or part of, the Gly4-Glu21 segment of the human cysteine proteinase inhibitor cystatin C have been synthesized. Peptides containing residues on the N-terminal side of Gly11 were rapidly cleaved by papain at the bond Gly11-Gly12 whereas a peptide starting at residue Gly11 was not, thus demonstrating 1. that the N-terminal segment of cystatin C has an amino acid sequenc

The article discusses the importance of data by sex in order to promote and advocate for gender mainstreaming into humanitarian assistance. It points at some of the weaknesses in data collection and management and makes recommendations on how to get the right data right.

Individuals may join groups for several reasons, one of which is the possibility of sharing information about the quality of a foraging area. Sharing information in a patch-foraging scenario gives each group member an opportunity to make a more accurate estimate of the quality of the patch. In this paper we present a mathematical model in which we study the effect of group size on patch-leaving po

Insertion of transposable elements is a major cause of genomic expansion in eukaryotes. Less is understood, however, about mechanisms underlying contraction of genomes. In this study, we show that retroelements can, in rare cases, be precisely deleted from primate genomes, most likely via recombination between 10- to 20-bp target site duplications (TSDs) flanking the retroelement. The deleted loci

OBJECTIVE: To perform an ecological study in an effort to generate questions concerning the preventive impact of various cardiovascular drugs on mortality from stroke and ischaemic heart disease (IHD) in the community, and to explore the association between sales of nitrates and mortality from stroke and IHD. METHODS: Out-patient drug utilization (sales) of blood pressure lowering drugs, lipid low

OBJECTIVE: To analyze the local circulatory effects of prostacyclin in skeletal muscle. DESIGN: A prospective experimental study. SETTING: A university laboratory. SUBJECTS: Twelve adult cats. INTERVENTIONS: The study was performed on autoperfused, sympathectomized gastrocnemius muscle. MEASUREMENTS AND MAIN RESULTS: Arterial blood flow, total and segmental vascular resistances (arterial vessels o