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The response to antihypertensive therapy is dependent on renal structural changes. A 5-year prospective study of renal biopsy in type 2 diabetic patients with micro-macroalbuminuria.

A substantial fraction of patients with diabetes mellitus develop end-stage renal disease. We wanted to study the influence of renal structural changes on the response to treatment of the systemic blood pressure (BP) in type 2 diabetic patients with micro- or macroalbuminuria. METHODS: A 5-year observational prospective study of 40 type 2 diabetic patients. Renal biopsy was performed on the indica

Vanliga fördomar inom byggbranschen

Det har funnits och fortfarande finns ett antal fördomar inom byggbranschen. Som exempel kan nämnas "täta fasadbehandlingar kväver huset" och "naturmaterial medför ett sunt hus". I denna artikel diskuteras ett urval fördomar som antingen medfört en intensiv debatt eller sämre konstruktioner och i vissa fall även onödiga skador.

EVAR of Aortoiliac Aneurysms with Branched Stent-grafts.

INTRODUCTION: Branched iliac stent-grafts (bSG) have recently been developed in order to preserve internal iliac artery (IIA) flow in patients with aneurysmal or short common iliac arteries. The aim of this study is to evaluate a single-center experience with bSG for the IIA. METHODS: Twenty-two male patients (70 (IQR 65-79) years old) underwent EVAR with 23 bSG (1 bilateral repair) between Septem

Organization of the human embryonic ventral mesencephalon.

The neurons in the ventral mesencephalon (VM) are organized into several nuclei consisting of distinct neuronal populations. These include the dopaminergic (DA) neurons of the substania nigra and ventral tegmental area, the oculomotor (OM) neurons that innervate the muscles controlling eye movement, and the reticular neurons of the red nucleus (RN) involved in motor control and coordination review

New treatments in hemophilia: insights for the clinician.

Hemophilia has evolved from an often fatal hereditary bleeding disorder to a disorder for which safe and effective treatment is available. However, there are several challenges remaining in the treatment of hemophilia. Prophylaxis to prevent bleeding is costly and requires frequent intravenous injections, which are cumbersome for patients. Venous access is often difficult to achieve, especially in

Sickness absence among cancer patients in the pre-diagnostic and the post-diagnostic phases of five common forms of cancer.

PURPOSE: The purpose of this study was to observe sickness absence before and after the cancer diagnosis among cancer patients with five common forms of cancer. METHODS: Using cohort data, we observed sick leave in the pre- and post-diagnostic phase among patients with colon, rectal, breast, prostate, or lung cancer (n = 2,738). We also identified reference subjects without cancer (total n = 12,24

Pharmacogenetic implications for eight common blood pressure-associated single-nucleotide polymorphisms.

OBJECTIVE:: We aimed to test whether eight common recently identified single-nucleotide polymorphisms (SNPs), strongly associated with blood pressure (BP) in the population, also have impact on the degree of BP reduction by antihypertensive agents with different mechanisms. METHODS:: In 3863 Swedish hypertensive patients, we related number of unfavorable alleles of each SNP (i.e. alleles associa