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Update on non-typeable Haemophilus influenzae-mediated disease and vaccine development

Introduction: Non-typeable Haemophilus influenzae (NTHi) has attracted more interest in recent years due to an increased prevalence of infections caused by the pathogen. This upsurge is at least partly ascribed to the introduction of the pneumococcal conjugated vaccines that has resulted in an aetiological shift in NTHi’s favor with respect to upper respiratory tract infections. Moreover, an incre

Detailed chemical compositions of the wide binary HD 80606/80607 : Revised stellar properties and constraints on planet formation

Differences in the elemental abundances of planet-hosting stars in binary systems can give important clues and constraints about planet formation and evolution. In this study we performed a high-precision, differential elemental abundance analysis of a wide binary system, HD 80606/80607, based on high-resolution spectra with high signal-to-noise ratio obtained with Keck/HIRES. HD 80606 is known to

The walking stick in the nineteenth-century city : Conflicting ideals of urban walking

This article reflects on the role of the walking stick in the nineteenth-century city and explores the nature of the criticisms directed at it. The criticism and mocking of certain ways of holding the cane display the deep conflicts within the culture of urban strolling concerning how to take part in it, and who were allowed to do so. By identifying an irritation with canes, we see that there was

Search for Higgs boson decays to beyond-the-Standard-Model light bosons in four-lepton events with the ATLAS detector at √s=13 TeV

A search is conducted for a beyond-the-Standard-Model boson using events where a Higgs boson with mass 125 GeV decays to four leptons (ℓ = e or μ). This decay is presumed to occur via an intermediate state which contains one or two on-shell, promptly decaying bosons: H → ZX/XX → 4ℓ, where X is a new vector boson Zd or pseudoscalar a with mass between 1 and 60 GeV. The search uses pp collision data

Workplace relationships impact self-rated health : A survey of Swedish municipal health care employees

Background: The impact of positive social relationships on the health of municipal employees in the elder care sector in Sweden needs further examination. OBJECTIVE: To explore the association between health and relationships among elderly care employees using a salutogenic perspective. METHOD: Survey of all employees (n = 997) in special housing, home care and Disabled Support and Services in a S

Migration, Transnationalism, and Social Change in Central Asia: Everyday Transnational Lives of Uzbek Migrants in Russia

There is an extensive research that explores the reproduction of transnational communities and relations, with a particular focus on locality, identity and culture. However, the existing literature on transnational migration is largely based on the case studies of immigrant communities living in the United States and Western Europe, while not much has been said about the transnational practices of

Framing Social Interaction : Continuities and Cracks in Goffman's Frame Analysis

This book is about Erving Goffman’s frame analysis as it, on the one hand, was presented in his 1974 book Frame Analysis and, on the other, was actually conducted in a number of preceding substantial analyses of different aspects of social interaction such as face-work, impression management, fun in games, behavior in public places and stigmatization. There was, in other words, a frame analytic co

On stability and conservation properties of (S)epirk integrators in the context of discretized pdes

Exponential integrators are becoming increasingly popular for stiff problems of high dimension due to their attractive property of solving the linear part of the system exactly and hence being A-stable. In practice, however, exponential integrators are implemented using approximation techniques to matrix-vector products involving functions of the matrix exponential (the so-called ϕ-functions) to m

FE simulation and experimental verification of side-flow and burr formation in machining of oxygen-free copper

This article considers the influence of cutting data on burr formation when machining oxygen-free copper in a longitudinal turning operation. Burr formation and side-flow frequently occur in a cutting process, resulting in highly undesirable poor surface integrity and reduced dimensional accuracy of the machined components. Finite Element (FE) simulations of a cutting process were used to simulate

Selecting Cutting Data Tests for Cutting Data Modeling Using the Colding Tool Life Model

An analysis on selecting cutting speed, cutting feed and depth of cut when collecting data for the Colding Tool Life Model based on Woxen's Equivalent Chip Thickness was performed to achieve the lowest possible model error. All possible combinations of a large data set were evaluated with regard to model error. This work shows that an increase of ratio between the highest and lowest cutting speed,

Analysis of eyewitness testimony in a police shooting with fatal outcome–Manifestations of spatial and temporal distortions

Eyewitness statements are commonly used in the criminal justice system and viewed as having a high-probative value, especially when the witness has no motive to lie, other witness recollection corroborates the account, or the witness is highly confident. A fatal police shooting incident in Sweden had 13 witnesses (nine civilians and four police officers) and was also filmed with two mobile phones.

Critical factors for the return-to-work process among people with affective disorders : Voices from two vocational approaches

Background: Depression is among the major causes of disability with a negative impact on both daily life and work performance. Whilst depression is the primary cause of sick-leave and unemployment in today's workplace there is a lack of knowledge of the needs of individuals with depression regarding their return-to-work (RTW) process. Objective: To explore which factors are of critical importance

Genome-wide Scan Identifies Role for AOX1 in Prostate Cancer Survival

We performed genome-wide association studies and found single nucleotide polymorphisms (SNPs) at seven independent loci associated with prostate-cancer-specific survival time. Two SNPs replicated in an independent cohort. The SNP rs73055188 at AOX1 is associated with AOX1 gene expression level, which is correlated with biochemical recurrence.