Transcriptional Burst Kinetics of Dosage Compensation in Chicken Sex chromosome combinations are different between sexes in many animal species. In therian mammals, females hold XX and males hold XY, which is called male heterogametic system. In birds, the sex chromosome system is female heterogametic (ZZ in males and ZW in females). The gene dosage imbalance between sexes (Xm:XXf or Zf:ZZm) and

Antimicrobial resistance (AMR) is a growing problem worldwide as more drug-resistant bacteria are identified. However, resistance is comparably rare against antibiotics that target the cytoplasmic membrane. Membrane thickness is an important factor for the mode of action of these antibiotics, and difficult to study. Thus, constructing a biosensor to measure membrane thickness in vivo is of great i

Sustainability transition research investigates why the necessary change towards more sustainable patterns of consumption and production has not yet been achieved and how it can be accelerated. Taking into account the complexity of the globalised dynamics underlying today's sustainability challenges, it has been suggested that the existence of global regimes limits the possibilities for change

Uppsatsen utforskar vilka historiedidaktiska perspektiv man kan tillämpa på de populära Assassin's Creed-spelen, med fokus på Assassin's Creed II och Assassin's Creed: Brotherhood. Historiebruk, historiekultur och historiemedvetande, vilka tillsammans bildar den historiedidaktiska teorin, utgör de teoretiska underlagen. Det metodologiska tillvägagångssättet är en kombinerad text- och b

Current post-carbon transition trajectories are primarily based on a belief in technical solutions wherein considerations of the citizens’ role in collective mobilisation and transformation are largely overlooked. To this end, the thesis seeks to understand how citizens can become active agents of change within transition efforts and how their political agency can be empowered accordingly. This, b

There are many advantages with the development towards Integrated Circuits (ICs) with smaller, faster, and more transistors. However, tighter margins lead to a need of on-chip instruments to test, tune, and configure. These on-chip instruments, which can be in the range of thousands per IC, must be accessed through the life-time. However, access is challenged by complex system hierarchies. When IC

The aim of this study was to examine pollution-induced community tolerance (PICT) of biofilm communities induced by chemical mixtures, characteristic of agricultural aquatic environments. Additionally, the use of biofilms as a natural passive sampler was investigated. In situ biofilms grown on artificial substrate for 4 to 6 weeks from sites located in agricultural areas were used to conduct a PIC

In this project, I start by addressing the issue of the creativity decrease that happen within children when they start school. I wanted to emphasize the importance of creative play to develop problem-solving skills. After I ran some user tests, my project took a new turn and instead I started designing a board game for an older target group. The aim of the game is to improve the visual comm

Maternal Rotavirus antibodies inhibit rotavirus specific B cell responses in offspring For infants, the period following birth is marked by a developmentally immature immune system and increasing exposure to pathogens, however it is also a period in which maternally derived antibodies are still present in the neonate. These antibodies are obtained during pregnancy through the placenta and follow

The construction industry is expected to generate 2.2 billion tons of waste by the year 2025 and was responsible for 39 % of GHG emissions generated by the building processes and energy consumption, in 2017. In 2018, the Swedish construction industry accounted for 21 % of the total GHG emissions (including imported emissions) and 35 % of the total amount of waste in the country. In these past deca

Hur cancerceller ska bli bättre på att göra sig synlig för immunförsvaret Immunförsvaret består utav många olika celler som alla är med i att försvara kroppen från hot, när dom upptäcker en fara finns en del celler som kan eliminera målet, dom kallas T-celler. Ett hot som uppkommer i kroppen är cancer. Det finns många olika orsaker till att cancer uppstår, däribland arvsanlag men också miljöfaktoThe many cases of malignant melanoma and the following relapses after standard-of-care treatment demands inventions on finding new treatment to this cancer disease. One of the reasons for reduced clinical response in melanoma is the downregulation of tumor specific antigens which results in decreased tumor recognition, followed by tumor escape and progression. This study investigated the potential

Transports, and transport infrastructures enable and deliver vital societal functions in today’s society. At the same time, as sustainability becomes more and more important these sectors fail to enable the rate of change that international and national policies calls for. The electrification of the transport sector is a key driver of the future’s sustainable transport system, and the number of el

Previous research has shown that intermediate-advanced L2 learners of Swedish with a non-tonal L1 can use word accents to predict the upcoming suffix as L1 Swedish speakers do. This was also the case of low-intermediate L2 learners who produced word accents after being instructed on the Swedish prosodic system. On the contrary, previous findings on L2 Swedish learners with a tonal L1 exhibited no

The project aims to learn about Chinese young people's choices and attitudes towards cooking and solve their problems in cooking. The solution is presented in the form of a product --- a multifunctional electrothermal cooking appliance. The traditional Chinese saying "Food is god for the people" shows the importance of diet in Chinese life. But today, more and more Chinese young peo

We live in a society where online shopping is becoming the most common form of shopping. Companies are investing and growing their online market by offering cheap and quick deliveries, online offers that beat in-store prices and increasing the number of package pick-up locations. We live a faster-paced lifestyle, which makes online shopping more convenient for us. The rapid change in our shopping

It has been shown that pollinators mediate selection on floral traits of food-deceptive orchids. However, few studies have disentangled the mechanisms linking floral traits to performance and fitness, providing an opportunity to gain a deeper understanding of the process of natural selection. In this project, we studied trait-performance-fitness relationships on three food-deceptive Dactylorhiza o

Physical Properties of Prebiotic Membranes One of the most fundamental questions in science that remains unanswered today is the question of the origin of life on Earth. Life is defined as a chemical system with the capacity of self-replication and undergoing Darwinian evolution. Origin of life research focuses on the transition of physics and chemistry to such a chemical system. For life to ari

Functional Data Analysis (FDA) is a field that has been growing rapidly over the last few decades, with much ongoing research and many recent publications. The focus for Functional Data Analysis is the study of so called functional data, that is data that is assumed to have been generated from a true, underlying function, where we can only observe a sequence of measurements. We propose a method t

Previous studies of the neural correlates of episodic memory formation have been limited because the design of experiments tended to restrict natural viewing behavior, and thus they overlooked the role of eye movements in memory formation. The goal of the present study is to offer new insights into understanding the neural mechanisms of episodic memory formation in naturalistic viewing at the leve

Arbetet presenterar en metod som uppskattar ljud så som en människa uppfattar det i ett rum. Metoden kan användas i exempelvis applikationer med augmented reality och brusreducering. Att kunna uppskatta ljud i ett ljudfält är en nödvändighet för många applikationer. I exempelvis aktivt brusreducerade hörlurar får man in en signal som man vill tysta genom att skicka ut en motsatt signal, som i teoThere are different ways of evaluating the sound pressure in a sound field. Doing so is an essential part of several applications, such as active sound control and voice analysis. One way of evaluating the sound pressure in a sound field is by measuring a few discrete points in the field, combined with an interpolation method to find the sound pressure for the remaining field. Recently, it has bee