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Artificial intelligence together with mechanical imaging in mammography
Artificial intelligence (AI) applications are increasingly seeing use in breast imaging, particularly to assist in or automate the reading of mammograms. Another novel technique is mechanical imaging (MI) which estimates the relative stiffness of suspicious breast abnormalities by measuring the distribution of pressure on the compressed breast. This study investigates the feasibility of combining
High throughput extracellular vesicle sorting using electrokinetic deterministic lateral displacement
We present a microfluidic device that can sort nanosized extracellular vesicles (EVs) based on electrokinetics and Deterministic Lateral Displacement (DLD). The device is made from PDMS using standard soft-lithography, can separate particles down to 200 nm, and what is more, can achieve almost two orders of magnitude higher throughput than an otherwise single electrokinetic DLD device.
Evolution of the Microstructure and Mechanical Properties of cBN-Based Cutting Tools with Silicides Compounds as Binder Phase
Silicide based compounds are widely used for coatings due to their high melting temperature, oxidation resistance and moderate density. Employment of binders based on silicides of transitional metals can provide cBN-based cutting tools with higher chemical stability and better performance. The relationship between phase composition, microstructure and mechanical properties of novel polycrystalline
Evaluation of progressive damage in barre granite using ultrasonic velocity tomography and digital image correlation
Full-field measurement techniques have the significant advantage of taking measurements along the complete specimen specially assisting in the characterization of heterogeneous rocks. This research's objective was therefore to evaluate and characterize the damage occurring inside uniaxially-loaded Barre granite specimens using two non-destructive full-field measurement techniques, namely, the ultr
Why Economic Management Models Do Not Foster Morals
Environmental and anthropogenic correlates of migratory speeds among Atlantic salmon smolts
Dams, weirs, and hydropower facilities are often cited as migratory barriers which impart significant reductions in fitness among migratory fish species. Even where upstream and downstream passage options are available, barrier passage can still often result in energetic or physical costs which compound delays or cause mortality. Past studies have identified variables associated with such fitness
Fatigue after heart transplantation – a possible barrier to self-efficacy
Rationale: Recovery after heart transplantation is challenging and many heart recipients struggle with various transplant-related symptoms, side-effects of immunosuppressive medications and mental challenges. Fatigue has been reported to be one of the most common and distressing symptoms after heart transplantation and might therefore constitute a barrier to self-efficacy, which acts as a moderato
MSIWarp : A General Approach to Mass Alignment in Mass Spectrometry Imaging
Mass spectrometry imaging (MSI) is a technique that provides comprehensive molecular information with high spatial resolution from tissue. Today, there is a strong push toward sharing data sets through public repositories in many research fields where MSI is commonly applied; yet, there is no standardized protocol for analyzing these data sets in a reproducible manner. Shifts in the mass-to-charge
Pseudoaneurysm Development after Drug-Eluting Balloon (DEB) Angioplasty of a Venous Femoropopliteal Bypass Graft
Endovascular recanalization of occluded venous femoropopliteal bypass grafts is widely used because of easy access. This case report describes pseudoaneurysm developing 4 weeks after endovascular recanalization of an occluded in situ venous femoropopliteal graft. The patient was treated for a popliteal aneurysm with a venous femoropopliteal bypass graft, which subsequently occluded. Four weeks aft
Assessment of search strategies in literature-review-based candidate theses within a nursing program
Background: The majority of candidate theses in baccalaureate nursing programs in Sweden are written as literature studies. Being able to carry out a systematic and structured literature search is an essential part of thesis-related work. Aim: The aim of the current study was to investigate changes in nursing students’ search strategies in candidate theses. Methods: A retrospective, quantitative s
Megakaryocytes listen for their progeny’s progeny during inflammation
Improving Performance of Feedback-Based Real-Time Networks using Model Checking and Reinforcement Learning
Traditionally, automatic control techniques arose due to need for automation in mechanical systems. These techniques rely on robust mathematical modelling of physical systems with the goal to drive their behaviour to desired set-points. Decades of research have successfully automated, optimized, and ensured safety of a wide variety of mechanical systems. Recent advancement in digital technology ha
Australian Bogong moths Agrotis infusa (Lepidoptera : Noctuidae), 1951–2020: decline and crash
The Bogong moth Agrotis infusa is well known for its remarkable long-distance migration – a return journey from the plains of southeast Australia to the Australian Alps – as well as for its cultural significance for Indigenous Australians. Each Spring, as many as four billion moths are estimated to arrive in the Australian Alps to aestivate in cool mountain caves and in boulder fields, bringing wi
Temperature adaptation of soil microbial respiration in alpine, boreal and tropical soils : An application of the square root (Ratkowsky) model
Warming is expected to stimulate soil microbial respiration triggering a positive soil carbon-climate feedback loop while a consensus remains elusive regarding the magnitude of this feedback. This is partly due to our limited understanding of the temperature-adaptive response of soil microbial respiration, especially over broad climatic scales. We used the square root (Ratkowsky) model to calculat
The effect of breast density on the performance of deep learning-based breast cancer detection methods for mammography
Mammographic sensitivity in breasts with higher density has been questioned. Higher breast density is also linked to an increased risk for breast cancer. Even though digital breast tomosynthesis (DBT) offers an attractive solution, for varied reasons it has not yet been widely adopted in screening. An alternative could be to boost the performance of standard mammography by using computer-aided det
Personalised breast cancer screening with selective addition of digital breast tomosynthesis through artificial intelligence
Breast cancer screening is predominantly performed using digital mammography (DM), but higher sensitivity has been demonstrated with digital breast tomosynthesis (DBT). A partial DBT screening in selected groups with a clear benefit from DBT might be more feasible than a full implementation, and using artificial intelligence (AI) to select women for DBT might be a possibility. This study used data
Evaluation of a flat fielding method for simultaneous DBT and MI acquisition
We are developing a prototype system for simultaneous digital breast tomosynthesis (DBT) and mechanical imaging (MI). MI maps the local pressure distribution during clinical exams, to distinguish breast abnormalities from the normal tissue. Both DBT alone, and MI when combined with digital mammography, have demonstrated the ability to reduce false positives; however, the benefit of combining DBT w
Adjacent Primary Care May Reduce Less Urgent Pediatric Emergency Department Visits
Aims: Pediatric emergency department (ED) overcrowding is a challenge. This study was designed to evaluate if a hospital-integrated primary care unit (HPCU) reduces less urgent visits at a pediatric ED. Methods: This retrospective cross-sectional study was carried out at a university hospital in Sweden, where the HPCU, open outside office hours, had been integrated next to the ED. Children seeking
Certification of students in non-technical engineering skills : What do the companies think?
To systematically address non-technical engineering skills (NTES), six mandatory "Engineering Days" (Ing-dagar) were introduced in two bachelor programmes. The students were also allowed to perform voluntary activities leading to a Certification of Non-technical Engineering Competences, a certificate the students can attach to their CVs. To be certified, the student must have performed activities