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New standardized cystatin C and creatinine GFR equations in children validated with inulin clearance

This study compares glomerular filtration rate (GFR) equations in children based on standardized cystatin C (CYSC) and creatinine (CREA) and their combinations with renal clearance of inulin (C-inulin). A total of 220 children with different renal disorders were referred for C-inulin (median 84 ml/min/1.73 m(2)). Bias, precision (interquartile range, IQR), and accuracy (percentage of estimates +/-

Search for dark matter in events with heavy quarks and missing transverse momentum in [Formula: see text] collisions with the ATLAS detector.

This article reports on a search for dark matter pair production in association with bottom or top quarks in [Formula: see text] of [Formula: see text] collisions collected at [Formula: see text] TeV by the ATLAS detector at the LHC. Events with large missing transverse momentum are selected when produced in association with high-momentum jets of which one or more are identified as jets containing

MCM2 expression levels predict diagnosis and prognosis in gastric cardiac cancer

Background: Gastric Cardiac Cancer (GCC) has high incidence and poor prognosis requiring early screening of high-risk populations. Minichromosome maintenance (MCM) proteins are used as diagnostic-biomarkers in many cancers but not validated for GCC. We evaluate MCM protein 2 (MCM2), comparing it with the validated markers Ki67 and PCNA. Methods: GCC and corresponding cardiac precancerous samples w

Role of complement and complement regulators in the removal of apoptotic cells

Apoptosis, followed by rapid phagocytic clearance, is the primary mechanism by which organisms dispose of unwanted cells. The intracellular and extracellular composition of an apoptotic cell changes to decrease immunogenicity and enhance its uptake. By changing their extracellular composition, apoptotic cells acquire the capacity to bind complement initiation molecules such as C1q and MBL. Binding

Secondhand Smoke Exposure Causes Bronchial Hyperreactivity via Transcriptionally Upregulated Endothelin and 5-hydroxytryptamine 2A Receptors.

Cigarette smoke exposure is strongly associated with airway hyperreactivity (AHR) which is the main characteristic seen in asthma. The intracellular MAPK signaling pathways are suggested to be associated with the airway damage to the AHR. In the present study, we hypothesize that secondhand cigarette smoke (SHS) exposure upregulates the bronchial contractile receptors via activation of the Raf/ERK

Hyperfine structure and hyperfine coherent properties of praseodymium in single-crystalline La-2(WO4)(3) by hole-burning and photon-echo techniques

We studied the hyperfine structure and hyperfine coherent properties of the H-3(4)(0)-> D-1(2)(0) transition of Pr3+ ions in a tungstate single crystal La-2(WO4)(3) by hole-burning and photon-echo techniques. This work is motivated by the search of an efficient three level Lambda system in this new compound with which we could build up a quantum memory. By nonconventional hole-burning experiments,

How Wild is Iceland? Wilderness Quality with Respect to Nature-based Tourism

The Icelandic highlands are one of the few places left in Europe where tourists can experience pristine wilderness. During the past decades the highlands have, however, witnessed a rapid expansion in natural resource exploitation. This study attempts to evaluate the pristine condition of Icelandic wilderness by testing different methods of identifying and analysing wilderness with respect to natur

Att sminka de döda

Mitt paper handlar om den amerikanska tv-serien Six Feet Under, och i fokus för min framställning står berättelsens behandling av föreställningar om döden som knuten till naturen och som något ”naturligt” – satt i relation till kultur och estetik. I Six Feet Under behandlas en rad ämnen centrala för det västerländska samhällets diskurser om natur, kultur, moral och existens. Serien fick ett stort

Bird or bat: comparing airframe design and flight performance.

Birds and bats have evolved powered flight independently, which makes a comparison of evolutionary 'design' solutions potentially interesting. In this paper we highlight similarities and differences with respect to flight characteristics, including morphology, flight kinematics, aerodynamics, energetics and flight performance. Birds' size range is 0.002-15 kg and bats' size range is 0.002-1.5 kg.

Smoking and lymphoma risk in the european prospective investigation into cancer and nutrition

Lymphomas are one of the few cancers that have been increasing in incidence over the past decades. So far, only a few established risk factors have been identified, including immunosuppression and viral infections. Recent evidence suggests etiologic heterogeneity of different lymphoma subtypes. Smoking may affect risk differently, depending on the lymphoma entity. The European Prospective Investig

Influence of humic substances on bacterial and viral dynamics in freshwaters

Bacterial and viral abundances were measured in 24 lakes with dissolved organic carbon (DOC) concentrations ranging from 3 to 19 mg of C liter(-1). In addition, a laboratory experiment was performed to test the effects of different sources of carbon (i.e., glucose and fulvic acids) and nutrients on the dynamics of viruses and bacteria. In the lake survey, no correlation was found between virus abu

Selective antiproliferative activity of hydroxynaphthyl-beta-D-xylosides

The antiproliferative activity of the 14 isomeric monoxylosylated dihydroxynaphthalenes has been tested in vitro toward normal HFL-1 and 3T3 A31 cells as well as transformed T24 and 3T3 SV40 cells. The antiproliferative effect toward HFL-1 cells was correlated with the polarity of the compounds. However, in the case of transformed T24 cells, some compounds showed a clearly different behavior resul

Behavioral interference and facilitation in the foraging cycle shape the functional response

Individual forager behaviors should affect per capita intake rates and thereby population and consumer-resource properties. We consider and incorporate conspecific facilitation and interference during the separate foraging-cycle stages in a functional response model that links individual behavioral interactions with consumer-resource processes. Our analyses suggest that failing to properly conside

Functional activity of the complement regulator encoded by Kaposi's sarcoma associated herpesvirus.

Kaposi's sarcoma-associated herpesvirus (KSHV) is closely associated with Kaposi's sarcoma and certain B-cell lymphomas. The fourth open reading frame of the KSHV genome encodes a protein (KSHV complement control protein (KCP, previously termed ORF4)) predicted to have complement-regulating activity. Here, we show that soluble KCP strongly enhanced the decay of classical C3-convertase but not the