Whereas autonomic dysfunction and the metabolic syndrome are clinically associated, the relationships with the plasma metabolome is unknown. We explored the association between orthostatic blood pressure responses and 818 plasma metabolites in middle-aged subjects from the general population. We included 3803 out of 6251 subjects (mean age, 57 years; 52% women) from the Malmö sub-cohort of The Swe

Riksbanken behöver ta ansvar för den experimentella penning­politik som lett till miljard­förlusterna på värdepapper vi nu ser. Det skriver Fredrik N G Andersson och Lars Jonung.

The reliable and regular modification of the surface properties of substrates plays a crucial role in material research and the development of functional surfaces. A key aspect of this is the development of the surface pores and topographies. These can confer specific advantages such as high surface area as well as specific functions such as hydrophobic properties. Here, we introduce a combination

In this article, we present an experimental study of microwave resonators made out of Josephson junctions. The junctions are embedded in a transmission line geometry so that they increase the inductance per length for the line. By comparing two devices with different input/output coupling strengths, we show that the coupling capacitors, however, add a significant amount to the total capacitance of

Electronic coherence signatures can be directly identified in the time–frequency maps measured in two-dimensional electronic spectroscopy (2DES). Here, we demonstrate the theory and discuss the advantages of this approach via the detailed application to the fast-femtosecond beatings of a wide variety of electronic coherences in ensemble dimers of quantum dots (QDs), assembled from QDs of 3 nm in d

In response to rapid climate change and increasing human pressure, a wide variety of taxa have shifted their distribution in the past decades (range shift), with important consequences for ecosystem services and human health and economy. However, it is not yet clear whether most species will be able to track their favourable habitats or lag behind the climate signal (migration lag). Studying the p

BACKGROUND: Diverticulitis and colorectal cancer (CRC) share epidemiological characteristics, but their relationship remains unknown. It is unclear if prognosis following CRC differ for patients with previous diverticulitis compared to those with sporadic cases and patients with inflammatory bowel disease or hereditary syndromes.AIM: The aim was to determine 5-year survival and recurrence after co

Bedömning av pedagogisk och vetenskaplig skicklighet ska göras med lika stor omsorg vidtjänstetillsättningar. Trots att detta har varit lagstadgat i Sverige sedan 1960-talet visar forskningatt det finns utmaningar förknippade med granskning av pedagogisk skicklighet. Svårigheten attgöra kvalificerade bedömningar gäller inte bara vid anställning och befordran. De allt vanligaresystemen för belöningAssessment of teaching and scientific competence should be done with equal care at appointments. Despite the fact that this has been legislated in Sweden since the 1960s, research shows that there are challenges associated with reviewing teaching portfolios. The difficulty in making qualified judgments does not only apply to hiring and promotion. As systems for awarding pedagogical competence at S

This paper explores acceleration of the finite element-boundary integral hybrid method using the adaptive cross approximation. Our code implementing the hybrid method in Python based on open source packages is briefly presented. A simple one-level version of the adaptive cross approximation is described and it is used to accelerate the boundary integral matrices. We present results for scattering

People in economically advantaged nations tend to evaluate their life as more positive overall and report greater well-being than people in less advantaged nations. But how does positivity manifest in the daily life experiences of individuals around the world? The present study asked 15,244 college students from 62 nations, in 42 languages, to describe a situation they experienced the previous day

Wireless charging of smartphones using inductive wireless power transfer (IWPT) has become very popular. However, the efficiency of IWPT systems can decrease substantially when the transmitting and receiving coils are not closely coupled. One popular approach to mitigate the efficiency degradation is to utilize higher frequency. However, the higher efficiency is only achieved at a specific range o

Biomedical research is the first step towards the creation of new medications and treatments that help to manage different types of health conditions and diseases. The prevention and cure of diseases would be practically impossible without such type of research. Although the drug discovery and development processes are far too costly, time-consuming, prone to failure, and have low success rate, to

Questions in causality, control, and reinforcement learning go beyond the classical machine learning task of prediction under i.i.d. observations. Instead, these fields consider the problem of learning how to actively perturb a system to achieve a certain effect on a response variable. Arguably, they have complementary views on the problem: In control, one usually aims to first identify the system

Context. The Gaia-ESO Public Spectroscopic Survey is an ambitious project designed to obtain astrophysical parameters and elemental abundances for 100 000 stars, including large representative samples of the stellar populations in the Galaxy, and a well-defined sample of 60 (plus 20 archive) open clusters. We provide internally consistent results calibrated on benchmark stars and star clusters, ex

Small cell lung cancer (SCLC) is characterized by rapid growth and high metastatic capacity. It has strong epidemiologic and biologic links to tobacco carcinogens. Although the majority of SCLCs exhibit neuroendocrine features, an important subset of tumors lacks these properties. Genomic profiling of SCLC reveals genetic instability, almost universal inactivation of the tumor suppressor genes TP5

Dark matter’s presence can be inferred from gravitational interactions and astrophysical observations, but its nature is still unknown. If dark matter is a particle, then we hope to complement these observations from space and understand its nature and interactions by producing it in controlled laboratory conditions. The Large Hadron Collider (LHC), hosted at the CERN laboratory in Switzerland, pr