Filetype
Definitive hematopoiesis emerges via an endothelial-to-hematopoietic transition in the embryo and placenta; however, the precursor cells to hemogenic endothelium are not defined phenotypically. We previously demonstrated that the induction of hematopoietic progenitors from fibroblasts progresses through hemogenic precursors that are Prom1+Sca1+CD34+CD45- (PS34CD45-). Guided by these studies, we an
Many signals must be integrated to maintain self-renewal and pluripotency in embryonic stem cells (ESCs) and to enable induced pluripotent stem cell (iPSC) reprogramming. However, the exact molecular regulatory mechanisms remain elusive. To unravel the essential internal and external signals required for sustaining the ESC state, we conducted a short hairpin (sh) RNA screen of 104 ESC-associated p
Ultrafast transient absorption spectroscopy and single-wavelength anisotropy measurements were used to study the effect of isomerization on the excited-state properties of fucoxanthin in polar and nonpolar solvents. The excitation wavelengths were 477 nm for all-trans-fucoxanthin, and 333 and 477 nm for cis-fucoxanthin. All transient absorption spectra of the fucoxanthin isomers in polar solvents
Variations in laser properties and data acquisition times introduced inconsistencies in Geoscience Laser Altimeter System (GLAS) data. The effect of data inconsistencies, on two GLAS height retrieval methods, from three study sites, are investigated and validated against airborne laser scanning (ALS) percentile heights, from three data sources: all/first return point clouds, and raster canopy heig
There is extensive duplication of accessions among collection holders globally. To save costs, unwanted duplication should be avoided. This issue has been addressed internationally. In Europe, there are currently 35 Brassica collections located in 24 countries. Duplication may be identified not only by surveying passport data and seed transactions, but also by applying morphological or genetic cha
Since the 1970s, the degrowth idea has been proposed by scholars, public intellectuals and activists as a powerful call to reject the obsession of neoliberal capitalism with economic growth, an obsession which continues apace despite the global ecological crisis and rising inequalities. In the past decade, degrowth has gained momentum and become an umbrella term for various social movements which
Spin-polarized calculations in solids have generally been confined to a global quantization axis to simplify both the theoretical model and its implementation in self-consistent codes. This approximation is justified as many materials exhibit a collinear magnetic order. However, in recent years much interest has been directed towards noncollinear magnetism in which the magnetization density is a c
BACKGROUND: The Genetics of Subsequent Coronary Heart Disease (GENIUS-CHD) consortium was established to facilitate discovery and validation of genetic variants and biomarkers for risk of subsequent CHD events, in individuals with established CHD. METHODS: The consortium currently includes 57 studies from 18 countries, recruiting 185 614 participants with either acute coronary syndrome, stable CHD
Popular Abstract in English Soil as an ecosystem is a reservoir for several living organisms including microorganisms, earthworms, collembolans, nematodes and protozoans. They are involved in cycling the nutrients through degrading the organic compounds (source of carbon essential for all living organisms) like plant residues and respire part of it as carbon dioxide. Organic compounds get stored iAbstract Intensive land use in agriculture can lead to higher loss of biodiversity in soils and subsequently carbon due to tillage and application of pesticides and fertilizers. The microbial communities are pivotal to ecosystem processes in soil such as nutrient cycling, soil formation and plant productivity and thus are affected by land use. The main aim of this thesis is to understand the effe
The objective of this paper is to briefly examine and contrast the two audiovisual productions of Swedish author Stieg Larsson’s first novel The Girl with the Dragon Tattoo from the perspective that the two films were prepared, shot and finalized within vastly dissimilar production economies. The rationale behind the examination is that it seemingly reveals certain paradoxes that appear to challen
How coordination of metal ions modulates protein structures is not only important for elucidating biological function but has also emerged as a key determinant in protein turnover and protein-misfolding diseases. In this study, we show that the coordination of Zn2+ to the ALS-associated enzyme Cu/Zn superoxide dismutase (SOD1) is directly controlled by the protein's folding pathway. Zn2+ first cat
This dissertation explores the nexus between sustainable tourism development and corporate social responsibility (CSR). It addresses the scope for CSR to promote sustainable tourism in an international development context. This objective was pursued by exploring three sub-questions: what tools have been used to stimulate social responsibility in tourism; how has ecotourism influenced social respon
Linear-transmitters based on combined analog locked loop universal modulator (CALLUM) architectures are attractive, as they promise both high efficiency and high linearity. To date, it has not been possible to analyze a CALLUM transmitter as a linear feedback network due to the nonlinear nature of the control equations governing it. The main purpose of this paper has been the derivation of a linea
This paper presents results from an interview investigation with teachers in Swedish nurse education especially interested in internationalising the education. The aim has been to study teachers' understandings and experiences of internationalisation against the backdrop of the strong concern for internationalisation expressed in policy documents. The results are seen in the context of globalisati
Biopsychosocial problems experienced by renal disease patients were studied within a contextual framework the patients themselves defined, the findings being related to sociodemographic and medical data. Participants were 72 predialysis patients and 73 patients being treated by haemodialysis or peritoneal dialysis (106 men and 39 women, aged 18-84 years). Both stress-related global and situational
I use Google News TM to study the relation between news volumes and stock market volatilities. More than nine million stock market-related news stories in English and (Mandarin) Chinese are collected and the dynamics of the news volume and the stock market volatility is compared in both the Anglophone world and the Sinophone world. I find that the stock market volatility and the number of publicly
