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Apolipoprotein E (apoE) is a protein involved in transport of lipids and has been implicated to play an important role in regeneration after nerve injury. Determination of apoE in cerebrospinal fluid (CSF) thus have a potential interest when studying different forms of brain damage and as a marker of ongoing regenerative processes in the brain. However, previous studies on CSF-ApoE in Alzheimer's
Abstract is not available
One relevant challenge in the field of sustainable mobility is to plan and operate transport services equitable from a geographical and a social point of view. New forms of mobility can exacerbate pre-existing inequalities in the access to public transport systems by excluding some urban areas such as low-income neighborhoods or outskirts, where residents could benefit most from more supply. The g
Abstract The aim of this paper was to find out whether Swedes with a good knowledge of the Italian language were capable of laughing and reacting at the jokes of the Italian comedian Antonio Albanese through his fictional character, Cetto La Qualunque. The focusing point was to determine which linguistic features alongside non-linguistic features (i.e., body language and mimic above all), would
The present study investigates family-related language practices of Moldovan mothers emigrated to Italy, through a semi-structured interview. To date, few studies have considered linguistic choices in relation to educational practices and identity aspects in this population. Ten Moldovan woman have been interviewed. Results from a thematic analysis on the collected interviews has highlighted a co
Context. 55 Cnc e is an ultra-short period super-Earth transiting a Sun-like star. Previous observations in the optical range detected a time-variable flux modulation that is phased with the planetary orbital period, whose amplitude is too large to be explained by reflected light and thermal emission alone. Aims. The goal of the study is to investigate the origin of the variability and timescale o
Alzheimer's disease (AD) and frontotemporal dementia (FTD) are characterized by progressive neuronal loss and microvacuolization, although with different distributions of cortical involvement. In contrast to AD there is no amyloid, senile plaques or tangles in FTD. The involvement of chromosome 19 in AD has been associated with apoliprotein E (ApoE) and the epsi4 gene frequency has been related to
Inheritance of the apolipoprotein E (ApoE) ε4 allele is a risk factor for Alzheimer's disease (AD) and is associated with increased deposition of β-amyloid (Aβ) in AD, Down's syndrome, and normal aging. Aβ deposition in the form of senile plaques (SPs) has recently been described in patients with temporal lobe epilepsy (TLE). We studied the relationship between ApoE ε4 genotype and the deposition
OBJECTIVE: To verify, in an open study, the efficacy and safety of long-term administration of low weekly doses (5 mg) of methotrexate (MTX) i.m. in different stage rheumatoid arthritis patients.PATIENTS AND METHODS: The study has been performed for 24 months in 42 patients (37 females and 5 males), fulfilling the ARA criteria for rheumatoid arthritis. Main functional parameters, main serological
