Filetype
The retinoblastoma gene product (pRb) is involved in both cell cycle regulation and cell differentiation. pRb may have dual functions during cell differentiation: partly by promoting a cell cycle brake at G(1) and also by interacting with tissue-specific transcription factors. We recently showed that pRb mediates differentiation of leukemic cell lines involving mechanisms other than the induction
Methylation in CpG sites of the PPARGC1A gene (encoding PGC1-α) has been associated with adiposity, insulin secretion/sensitivity indexes and type 2 diabetes. We assessed the association between the methylation profile of the PPARGC1A gene promoter gene in leukocytes with insulin secretion/sensitivity indexes in normoglycemic women. A standard oral glucose tolerance test (OGTT) and an abbreviated
BACKGROUND: Prostate cancers featuring an expansile cribriform (EC) pattern are associated with worse clinical outcomes following radical prostatectomy (RP). However, studies of the genomic characteristics of Gleason pattern 4 subtypes are limited.OBJECTIVE: To explore transcriptomic characteristics and heterogeneity within Gleason pattern 4 subtypes (fused/poorly formed, glomeruloid, small cribri
Prostate cancer is a highly heterogeneous disease, understanding the crosstalk between complex genomic and epigenomic alterations will aid in developing targeted therapeutics. We demonstrate that, even though snail family transcriptional repressor 2 (SNAI2) is frequently amplified in prostate cancer, it is epigenetically silenced in this disease, with dynamic changes in SNAI2 levels showing distin
AIMS: A history of preeclampsia is associated with at least a twofold increased risk of coronary artery disease (CAD), with unclear underlying mechanisms. This study aimed to investigate coronary plaque characteristics in women with a history of preeclampsia compared to women from the general population.METHODS: In this cross-sectional study, women with a history of preeclampsia from the Cardiovas
The structure and function of many proteins are regulated post-translationally through glycan attachment. These glycans, assembled via competing enzymatic reactions, generate diverse glycoform populations - variants sharing a protein backbone but differing in glycan structures. While current analyses often focus on individual glycoforms, we demonstrate that population-level glycoform analysis - in
BACKGROUND: Apolipoprotein M (ApoM) is associated with lower mortality in heart failure (HF) patients and protects against cardiac and kidney injury in mice.OBJECTIVES: The authors investigated dapagliflozin's cardiorenal effects by studying its association with ApoM in patients with HF with reduced ejection fraction.METHODS: We performed a secondary analysis of DEFINE-HF (Dapagliflozin Effects on
This viewpoint advocates for the inclusion of art in global health discourse and practice. We explore four areas in which art can be leveraged to improve global health: (1) to amplify disenfranchised voices, (2) to advance social justice activism, (3) to strengthen communities and individuals, and (4) to improve global health communication. Drawing on community-driven art initiatives, we argue for
BACKGROUND: As the global population ages, the demand for palliative care is expected to increase. However, studies show that older patients often receive inadequate palliative care, partly due to healthcare professionals lacking sufficient training and tools to identify and address palliative care needs effectively. This study aims to explore healthcare professionals' experiences regarding facili
Social services are adapting to an increasingly digital environment, with municipalities expectedto engage citizens through digital channels. This study investigates how clients seeking social as-sistance perceive and use digital tools as well as the challenges and opportunities that arise whenimplementing such technologies in line with public service values. The analysis draws on municipaldigitalSocial services are adapting to an increasingly digital environment, with municipalities expected to engage citizens through digital channels. This study investigates how clients seeking social assistance perceive and use digital tools as well as the challenges and opportunities that arise when implementing such technologies in line with public service values. The analysis draws on municipal digit
High-spin states have been populated in 11954Xe via the 96Mo(27Al,p3n) reaction at 133 MeV, using the JUROSPHERE γ-ray spectrometer to record triple γ-ray coincidences. The known level scheme has been significantly extended and several band crossings identified. In particular, the νh11/2 yrast band has been extended to Iπ = (83/2-) and shows features which are consistent with those of smooth band
Bakgrund Tidigare studier indikerar att det kan finnas en fördel med att utföra konditionsträning under rehabiliteringen för patienter med främre korsbandsskada. Kunskapen om hur mycket konditionsträning som ingår i rehabiliteringsperioden för patienter med främre korsbandsskada är inte tillräckligt beskriven i litteraturen. Syfte Huvudsyftet med denna studie är att undersöka om och hur kondition
LUNDS TEKNISKA HÖGSKOLA TENTAMENSSKRIVNING MATEMATIK FMAA50 – Analys 2 2024-08-19 kl. 14.00–19.00 Hjälpmedel: formelblad Lösningarna ska vara försedda med ordentliga motiveringar och svaren ska förenklas max- imalt. 1. Beräkna a) ∫ 5 0 x √ x dx, (0.2) b) ∫ 4 −1 3x− 8 (x+ 2)(x− 5) dx, (0.4) c) ∫ π 0 sinx 1 + cos2 x dx. (0.4) 2. Lös begynnelsevärdesproblemen a) x2y′ + xy = 1, x > 0, y(1) = 1
https://www.maths.lu.se/fileadmin/matematik_lth_hbg/Analys_2/Tentor/Tentamen_Analys_2_240819.pdf - 2026-09-07
Språk och litteraturcentrum, vårterminen 2018 Har du aktiverat ditt studentkonto? Aktivera ditt Studentkonto på https://passport.lu.se med hjälp av inloggningsuppgifterna från antagning.se. Studentkontot behöver du för att till exempel komma åt undervisningsplattformen, trådlösa nätverk och studentmejl. Om du redan har ett aktivt konto behöver du inte aktivera det igen. Logga in på studentportal
https://www.sol.lu.se/media/utbildning/dokument/kurser/SPAM07/20181/V_lkomstbrev_VT18_SPAM07.docx - 2026-09-06
Vårterminen 2012 Litteraturlista för SVEA22, Svenska som andraspråk – fortsättningskurs, 31-60 hp, termin 2 Litteraturlistan fastställd av lärarkollegium 1 vid Språk- och litteraturcentrum den 17 december 2008, senast reviderad den 30 november 2011. Delkurs 4: Textkunskap (7,5 hp) Hellspong, Lennart och Ledin, Per, 1997: Vägar genom texten. Handbok i textanalys. Lund : Studentlitteratur (Enl. anv.
https://www.sol.lu.se/media/utbildning/dokument/kurser/SVEA22/20121/SVEA22_term_2_v12_med_andr.pdf - 2026-09-06
Litteraturlista FPPA22 - VT23 Sida 1 av 2 Filosofiska institutionen LITTERATURLISTA VT2023 FPPA22, Praktisk filosofi: Praktisk filosofi, politik och ekonomi – fortsättningskurs, 30 hp Fastställd av Filosofiska institutionens studierektor 2022-11-30 Delkurs 1 – Fördjupad moralfilosofi Hare, Richard: Moral Thinking. Oxford: Clarendon Press, 1981. Svenska utgåvan Moraliskt tänkande, Thales, 1994. Fis
https://www.fil.lu.se/media/utbildning/dokument/kurser/FPPA22/20231/Litteraturlista_FPPA22_VT2023.pdf - 2026-09-08
Litteraturlista FPPA23 - VT26 Sida 1 av 2 Filosofiska institutionen LITTERATURLISTA VT2026 FPPA23, Praktisk filosofi: Praktisk filosofi, politik och ekonomi – fortsättningskurs, 30 hp Fastställd av Filosofiska institutionens studierektor 2025-10-30 Delkurs 1 – Fördjupad moralfilosofi Ross, D: The Right and the Good. Eds (Phillip Stratton-Lake) Oxford: Clarendon Press. 1930/2002. Fisher, Andrew: Me
https://www.fil.lu.se/media/utbildning/dokument/kurser/FPPA23/20261/Litteraturlista_FPPA23_VT2026.pdf - 2026-09-08
