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The botulinum neurotoxins are potent molecules that are not only responsible for the lethal paralytic disease botulism, but have also been harnessed for therapeutic uses in the treatment of an increasing number of chronic neurological and neuromuscular disorders, in addition to cosmetic applications. The toxins act at the cholinergic nerve terminals thanks to an efficient and specific mechanism of
Per oltre quarant’anni, la scrittura della storia nei paesi dell’Europa orientaleè stata fortemente condizionata dagli imperativi ideologici e propagandisticidei regimi comunisti. La storia, più di ogni altra disciplina umanistica, offrivagiustifi cazioni, e quindi legittimità, al potere. Indagare il rapporto tra storia epotere in questo ambito signifi ca tanto addentrarsi nella storia dei sociali
The thesis, moving from several critical points of the Italian industrial relation system, studies in which way the rules that regulate those systems can influence the competitiveness of the enterprises. For this scope are compared several European experiences such as the Italian, Spanish and French ones, with particular attention to the changes that have been put in place after the 2008 economic
Starting from the renewed interest in the enforceability of collective agreements brought by the so-called Fiat case, this essay examines the instruments introduced by collective bargaining to this end, studying their nature in both legal and economic terms. Lastly, it proposes several interventions — to be adopted through both a legislative and a collective-bargaining process — aimed at ensuring
Abstract in ItalianNel 2017 Dennis C. Rasmussen ha pubblicato The Infidel and the Professor: David Hume, Adam Smith, and the Friend-ship that Shaped Modern Thought (Princeton-Oxford, Princeton University Press). Si tratta di uno studio destinato a suscitare un vivace dibattito sia per quel che concerne la re-visione dell’immagine canonica dei due filosofi, sia per le implicazioni teoriche ad essa
Monte Carlo models of DIS e-gamma scattering must describe hard emissions as well as the soft and collinear limits. Comparison with the observed experimental hadronic energy flow has shown that various models underestimate the high-p_T contribution, in particular at low-x. We have attempted to tune the Herwig, Pythia and Ariadne models to improve the agreement with the data, and to understand the
In this paper, we assess the relationship between the environmental pillar score (the ‘E’ in ESG) and stock returns in the Swedish stock market. Specifically, we analyze the OMXS60 index, which comprises the 60 most traded assets on the Nasdaq OMX Stockholm Exchange, examining how environmental ratings correlates with the development of returns. Additionally, we investigate how this relationship i
Group exhibition. Curated by Sandra Vieira Jürgens + Emília Tavares. MNAC and Coleção de Arta Contemporânea do Estado. MNAC, Lisbon, Portugal. 18 April - 23rd June, 2024. Included work: "Night for Day".
Currently, more than one instrument has been found to be reliable and valid for the assessment of hospital admission appropriateness. However; data on the level of agreement among these methodologies are extremely scarce. The study was aimed at evaluating whether the percentages of organizational (in)appropriateness resulting from some of the most diffused instruments (Italian Appropriateness Eval
The morphologic and physiologic effects of vitamin E, a powerful antioxidant, on the autolysis and sporulation of Aspergillus nidulans FGSC26 were studied. In carbon-depleted submerged cultures, reactive oxygen species (ROS) accumulated in the cells and, concomitantly, progressing autolysis was observed, which was characterized by decreasing dry cell masses and pellet diameters as well as by incre
